Andy Robinson has named a Scotland side featuring six changes from that which finished the RBS Six Nations defeat to Italy as he seeks to arrest a run of poor results against Australia on Tuesday.
Glasgow prop Ryan Grant will win his first cap while Edinburgh centre Matt Scott will make his first start as he wins a second.
At least this time he will be able to prepare to play in his preferred position, unlike when his debut when he was called into the squad at 20 minutes notice, and then came off the bench to play at wing for the first time in his career.
Not all of Robinson's changes are through choice. Jim Hamilton is out after fighting on the final weekend of the Aviva Premiership season, while Castre refused to release Max Evans in time - much to the anger of the Scotland coach.
Grant has won the battle against Jon Welsh, his clubmate at Glasgow, who started the last match after Allan Jacobsen, who has been rested for the tour, twisted an ankle in the pre-game warm-up.
Scott, however, probably realised he had a strong chance of starting every game at inside centre after Graeme Morrison, who filled the berth in the last game, was left at home.
The one-off Test against the Wallabies will be played at Newcastle, in Australia's Hunter Valley, on Tuesday.