England can complete the Six Nations Grand Slam on Saturday with victory over Wales.
However the hosts in Cardiff will be no pushover, with a victory for themselves potentially seeing them retain their title.
Here, we take a look at the key match facts...
* The countries have met on 123 occasions - England lead the series 56-55, with 12 draws.
* Wales' record win in the series was a 25-0 victory in 1905, while England boast a best of 62-5 in a 2007 World Cup warm-up game (pictured).
* The last drawn Test between Wales and England produced a 13-13 scoreline in 1983.
* Victory for England on Saturday would give them a first Six Nations Grand Slam since 2003, and their 13th championship clean sweep overall.
* Wales have lost their last five games at the Millennium Stadium, suffering defeats against Argentina, Samoa, New Zealand, Australia and Ireland.
* Wales have not conceded a try for the last 275 minutes of Six Nations action. The last player to touch down against them was Ireland centre Brian O'Driscoll on February 2.
* England have scored at least one try in 11 of their 13 previous Six Nations meetings with Wales.
* Reigning champions Wales have not successfully defended a Five or Six Nations title since 1979.
* Wales need to beat England by seven points on Saturday - and stay ahead of them in tournament try-count - to win the title. Victory by eight points or more means try-count is irrelevant.
* Wales and England have each lost only one of their last nine Six Nations games.