Cheltenham, who drew 1-1 at Enfield in the FA Umbro Trophy on Saturday, could upset Reading, held 1-1 at home by Bury on Saturday, while Hereford who beat Dulwich 3-0 on Saturday, may surprise Tranmere.
Third Division Peterborough, who won 3-1 at Scunthorpe on Saturday, could knock out Second Division Walsall, who struggled to beat Chesterfield 3-2 on Saturday, while West Bromwich Albion should contain Stoke City, humiliated 6-0 at home by Birmingham on Saturday.
Bury appeal against Sheffield United, beaten 4-2 by Sunderland on Saturday, while Bristol Rovers, who won 2-1 at Plymouth on Saturday, might upset Ipswich, disappointingly held 0-0 by QPR at home on Saturday.
QPR might upset Middlesbrough, beaten 3-0 by Charlton on Saturday, while Wimbledon, despite losing 2-0 to Liverpool on Saturday have little to fear travelling to Wrexham, judging by the latter's 3-0 home defeat by Fulham on Saturday.
On Wednesday, Wolverhampton Wanderers, who annihilated Norwich 5-0 at Carrow Road on Saturday, should make a successful journey to Darlington, whose defence looked leaky despite their 4-2 victory at home to Colchester on Saturday.
Aston Villa, although held 1-1 at home by Leicester on Saturday, should dismiss Portsmouth, who lost 3-0 at home to Manchester City on Saturday, at Villa Park.
Arsenal, whose revival continued when they beat Leeds 2-1 on Saturday, can win at Port Vale, who went down 2-1 at Nottingham Forest on Saturday, while Sheffield Wednesday, who beat Newcastle 2-1 on Saturday, should beat Watford, who lost 2-0 at Burnley.Reuse content