Russell Wilson will attempt to guide the Seattle Seahawks to Super Bowl success

NFL: Seattle Seahawks to face Denver Broncos in Super Bowl

Seattle holds on to beat the San Francisco 49ers while the Broncos beat the New England Patriots to set up Super Bowl XLVIII

Tom Brady will go up against arch-rival Peyton Manning on Saturday

American Football: Cream rises to top as final battle for Super Bowl begins

It's Conference Championship weekend, and the four best teams in the NFL lock horns for a shot at the sport's ultimate prize

Sam Berns with his parents in March 2009, when he was 12 years old

Sam Berns: Teenager whose struggle with disease became the subject of an acclaimed HBO documentary

Sam Berns, who has died at the age of 17, was a teenager whose struggle with a rare genetic condition that accelerates the aging process became the subject of a television documentary. He died from complications of Hutchinson-Gilford progeria syndrome, commonly known as progeria. The Progeria Research Foundation was founded by his parents.

Anquan Boldin, right, and Quintin Mikel collide in last night’s NFC Divisional play-off

American Football: Colin Kaepernick guides wild cards San Francisco to a showdown in Seattle with top-seeded Seahawks

Niners quarterback completed 15 of 28 passes for 196 yards

Seattle, led by Russell Wilson, are favourites to win next month's Super Bowl

American Football: All eyes on rising star Russell Wilson as Seattle aim to end 35 years of hurt

For devotees of the NFL, this is as good as it gets – the divisional round of the play-offs, four games pitting the regular season’s finest against four challengers already battle-hardened by victory in last weekend’s ever-treacherous wild-card round. And in 2014 there’s an extra twist: the prospect that one of the longest, most painful droughts in US sport might be near an end.

New England Patriots quarterback Tom Brady

NFL Divisional Playoff: Indianapolis Colts v New England Patriots match preview

A look ahead to this weekend’s Divisional Playoff match at Gillette Stadium in New England

Mind games: San Diego’s quarterback Philip Rivers (centre) says his team have the right mentality to succeed

American Football: San Diego Chargers gather pace at right time for title tilt

Momentum, if not logic, favour Mike McCoy's men in Super Bowl race

Peyton Manning broke Tom Brady's record for touchdown passes in a season

NFL: Indianapolis Colts must beware a (Peyton) Manning scorned

Devastated by injury and dumped by his beloved team, one of the NFL’s all-time great quarterbacks is back in business and breaking records

Pittsburgh Steelers head coach Mike Tomlin was left to reflect on what could have been after his side missed out on the play-offs

NFL: It could have been so different for Pittsburgh had luck not played such a huge part

A round-up of the final week's NFL regular season action as the play-off berth's get locked down

Quarterback Peyton Manning #18 of the Denver Broncos and quarterback Tom Brady #12 of the New England Patriots

NFL: Tom Brady v Peyton Manning is a rivalry for the ages, and Sunday proved it

A round-up of the latest events and talking points from the world of NFL

Tom Brady of the Patriots was furious after the defeat to the Panthers

NFL round-up: Regardless of the non-call, the Carolina Panthers deserved to beat the New England Patriots

A debatable non-call on Monday night will steal the headlines, but week 11 saw the gap between the haves and have-nots increase further

Head coach Joe Philbin of the Miami Dolphins
Richie Incognito has given an interview to Fox Sports

NFL: Suspended Richie Incognito explains he is ‘not a racist’ whilst fellow Miami Dolphin team-mates defend him

Offensive Linesman has given first interview since being suspended

LeGarrette Blount #29 of the New England Patriots reacts after he scored a touchdown in the second half against the Pittsburgh Steelers

NFL round-up: Hazing and health concerns aside, week nine was a watershed moment for Pittsburgh Steelers

A look at the major talking points from week nine in the NFL

Peyton Manning

NFL: Winless and undefeated - the Manning's are worlds apart

A weekly look at the biggest talking points in the NFL

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Blundering Tony Blair quits as Middle East peace envoy – only Israel will miss him

Blundering Blair quits as Middle East peace envoy – only Israel will miss him

For Arabs – and for Britons who lost their loved ones in his shambolic war in Iraq – his appointment was an insult, says Robert Fisk
Fifa corruption arrests: All hail the Feds for riding to football's rescue

Fifa corruption arrests

All hail the Feds for riding to football's rescue, says Ian Herbert
Isis in Syria: The Kurdish enclave still resisting the tyranny of President Assad and militant fighters

The Kurdish enclave still resisting the tyranny of Assad and Isis

In Syrian Kurdish cantons along the Turkish border, the progressive aims of the 2011 uprising are being enacted despite the war. Patrick Cockburn returns to Amuda
How I survived Cambodia's Killing Fields: Acclaimed surgeon SreyRam Kuy celebrates her mother's determination to escape the US

How I survived Cambodia's Killing Fields

Acclaimed surgeon SreyRam Kuy celebrates her mother's determination to escape to the US
Stephen Mangan interview: From posh buffoon to pregnant dad, the actor has quite a range

How Stephen Mangan got his range

Posh buffoon, hapless writer, pregnant dad - Mangan is certainly a versatile actor
The ZX Spectrum has been crowd-funded back into play - with some 21st-century tweaks

The ZX Spectrum is back

The ZX Spectrum was the original - and for some players, still the best. David Crookes meets the fans who've kept the games' flames lit
Grace of Monaco film panned: even the screenwriter pours scorn on biopic starring Nicole Kidman

Even the screenwriter pours scorn on Grace of Monaco biopic

The critics had a field day after last year's premiere, but the savaging goes on
Menstrual Hygiene Day: The strange ideas people used to believe about periods

Menstrual Hygiene Day: The strange ideas people once had about periods

If one was missed, vomiting blood was seen as a viable alternative
The best work perks: From free travel cards to making dreams come true (really)

The quirks of work perks

From free travel cards to making dreams come true (really)
Is bridge the latest twee pastime to get hip?

Is bridge becoming hip?

The number of young players has trebled in the past year. Gillian Orr discovers if this old game has new tricks
Long author-lists on research papers are threatening the academic work system

The rise of 'hyperauthorship'

Now that academic papers are written by thousands (yes, thousands) of contributors, it's getting hard to tell workers from shirkers
The rise of Lego Clubs: How toys are helping children struggling with social interaction to build better relationships

The rise of Lego Clubs

How toys are helping children struggling with social interaction to build better relationships
5 best running glasses

On your marks: 5 best running glasses

Whether you’re pounding pavements, parks or hill passes, keep your eyes protected in all weathers
Joe Root: 'Ben Stokes gives everything – he’s rubbing off on us all'

'Ben Stokes gives everything – he’s rubbing off on us all'

Joe Root says the England dressing room is a happy place again – and Stokes is the catalyst
Raif Badawi: Wife pleads for fresh EU help as Saudi blogger's health worsens

Please save my husband

As the health of blogger Raif Badawi worsens in prison, his wife urges EU governments to put pressure on the Saudi Arabian royal family to allow her husband to join his family in Canada