Life and Style Tamiflu: The £424m drug – that may not work

Damning report by MPs warns that doctors and patients are being ‘undermined’ on treatment options

Market Report: FTSE tips back into red

The FTSE was in a holding pattern most of the day, but in late trading just tipped back into the red, down 5.29 to 6,439.96.

Market Report: Imagination could see its market share slip to 32 per cent, according to the analysts

Smartphone microchip designers have received mixed signals from the City.

Bosses of companies in Britain's FTSE 100 index have enjoyed a 14 per cent boost in total pay

Top company bosses’ pay rising at 20 times rate of ordinary workers

FTSE 100 directors’ total remuneration up 14 per cent on share award deals

Market Report: Halfords gained from a UK surge in cycling and cost cutting at the group

There were at least some punters who could tear themselves away from Twitter's initial public offering long enough to pump up cycling and car parts retailer Halfords' share price yesterday.

Former BG Group boss Sir Frank Chapman

The richest pensioner on the FTSE 100: Former boss of BG Group, Sir Frank Chapman, has pot worth more £22m

Sir Frank Chapman, the former boss of oil and gas company BG Group, is revealed as the richest pensioner in the FTSE 100 with a pot worth more than £22m when he stepped down.

Astra in $500m US buy to boost cancer pipeline

UK drugs giant AstraZeneca took a further step to bolster its pipeline of new cancer drugs yesterday by agreeing to acquire privately held US biotech company Amplimmune for up to $500m (£321m).

The Business Matrix: Tuesday 27 August 2013

Tradesmen ‘work the longest hours’

The Business Matrix: Thursday 1 August 2013

Hugo Boss pins hopes on women

The drugs giant has been embroiled in a scandal but its shares have only wavered a little

Investment Insider: The heady days aren't over for drugs groups

Genetics, stem cells and consistent dividends can offset the problems of expiring patents

Simon Lowth moves from AstraZeneca to BG Group for less pay

BG Group has poached Simon Lowth from AstraZeneca to be its finance director. Mr Lowth, who was interim chief executive of the drug maker last year, is taking a pay cut to move to the FTSE 100 oil and gas company.

Developers bet on Crossrail boom with West End investment

Two of Britain’s top property groups are spending almost £700 million on West End developments, placing major bets on the success of Crossrail.

AstraZeneca’s £93m headache as it dumps another new drug

Struggling AstraZeneca today faced yet another blow when it had to dump a new arthritis treatment because clinical trials showed patients were hit with side-effects including the common cold.

AstraZeneca buys fish-oils drug maker Omthera

AstraZeneca is spending up to $443m (£293m) to buy a US heart-medicine business in an attempt to resuscitate the drug maker's dwindling pipeline of new products.

Unions fight Astra plans to move R&D base south

Union leaders will meet executives at AstraZeneca today to try to convince Britain's second-biggest drugmaker to reverse plans to close its R&D site in Cheshire and move almost 2,000 jobs.

James Ashton: AGMs season can still put trouble on agenda

Like the first swallow of summer, Barclays’ shareholder meeting this week signified the beginning of the AGM season. But if signs of summer are upon us, what happened to this year’s shareholder spring?

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Independent Travel
Lake Garda, Venice & Verona from £629pp
Dubrovnik
Vietnam
Bruges
South Africa
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Prices correct as of 12 December 2014
Homeless Veterans appeal: 'You look for someone who's an inspiration and try to be like them'

Homeless Veterans appeal

In 2010, Sgt Gary Jamieson stepped on an IED in Afghanistan and lost his legs and an arm. He reveals what, and who, helped him to make a remarkable recovery
Could cannabis oil reverse the effects of cancer?

Could cannabis oil reverse effects of cancer?

As a film following six patients receiving the controversial treatment is released, Kate Hilpern uncovers a very slippery issue
The Interview movie review: You can't see Seth Rogen and James Franco's Kim Jong Un assassination film, but you can read about it here

The Interview movie review

You can't see Seth Rogen and James Franco's Kim Jong Un assassination film, but you can read about it here
Serial mania has propelled podcasts into the cultural mainstream

How podcasts became mainstream

People have consumed gripping armchair investigation Serial with a relish typically reserved for box-set binges
Jesus Christ has become an unlikely pin-up for hipster marketing companies

Jesus Christ has become an unlikely pin-up

Kevin Lee Light, aka "Jesus", is the newest client of creative agency Mother while rival agency Anomaly has launched Sexy Jesus, depicting the Messiah in a series of Athena-style poses
Rosetta space mission voted most important scientific breakthrough of 2014

A memorable year for science – if not for mice

The most important scientific breakthroughs of 2014
Christmas cocktails to make you merry: From eggnog to Brown Betty and Rum Bumpo

Christmas cocktails to make you merry

Mulled wine is an essential seasonal treat. But now drinkers are rediscovering other traditional festive tipples. Angela Clutton raises a glass to Christmas cocktails
5 best activity trackers

Fitness technology: 5 best activity trackers

Up the ante in your regimen and change the habits of a lifetime with this wearable tech
Paul Scholes column: It's a little-known fact, but I have played one of the seven dwarves

Paul Scholes column

It's a little-known fact, but I have played one of the seven dwarves
Fifa's travelling circus once again steals limelight from real stars

Fifa's travelling circus once again steals limelight from real stars

Club World Cup kicked into the long grass by the continued farce surrounding Blatter, Garcia, Russia and Qatar
Frank Warren column: 2014 – boxing is back and winning new fans

Frank Warren: Boxing is back and winning new fans

2014 proves it's now one of sport's biggest hitters again
Jeb Bush vs Hillary Clinton: The power dynamics of the two first families

Jeb Bush vs Hillary Clinton

Karen Tumulty explores the power dynamics of the two first families
Stockholm is rivalling Silicon Valley with a hotbed of technology start-ups

Stockholm is rivalling Silicon Valley

The Swedish capital is home to two of the most popular video games in the world, as well as thousands of technology start-ups worth hundreds of millions of pounds – and it's all happened since 2009
Did Japanese workers really get their symbols mixed up and display Santa on a crucifix?

Crucified Santa: Urban myth refuses to die

The story goes that Japanese store workers created a life-size effigy of a smiling "Father Kurisumasu" attached to a facsimile of Our Lord's final instrument of torture
Jennifer Saunders and Kate Moss join David Walliams on set for TV adaptation of The Boy in the Dress

The Boy in the Dress: On set with the stars

Walliams' story about a boy who goes to school in a dress will be shown this Christmas