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Sian Smith: 'She's not in trouble. We just want her back'

A demonstration shows how the iKnife can slice through animal muscle

Surgical 'smart' knife that detects tumours could curb spread of cancer

A surgical knife that can detect when it is cutting through cancerous tissue is being tested in hospitals, raising hopes that the spread of cancer left behind after surgery could soon be curbed more successfully.

London in the 18th Century, By Jerry White

A century – and city – of duels, dung and gin cocktails

Almacantar revives flat plans for Centre Point

The owner of London's infamous concrete tower, Centre Point, will relaunch £350m plans to transform the 1960s-built block into luxury flats within weeks.

Lavazza joins coffee revolution with roll-out of shops

Italian coffee giant Lavazza plans to open nearly 400 shops over the next decade across the UK, in the latest sign of the British public’s seemingly insatiable demand for their daily caffeine hit.

Mary Dejevsky: Don't fall for commuter sob stories

If there is anything more infuriating than the predictable New Year fare increases on public transport, it is the equally predictable whingeing on the part of suburban rail commuters. Year after year they complain that they are uniquely victimised because they don't have a choice. They are captive passengers, crammed every day into obsolete rolling stock, sitting ducks for above-inflation fare rises.

Mark Lancaster, who claimed to work as an 'assessor' for SponsorAScholar.co.uk

Detectives investigating 'sex for tuition fees' website arrest man on suspicion of inciting prostitution

Detectives investigating a website offering to pay the tuition fees of female students in return for sex have arrested a man on suspicion of inciting prostitution.

Gary Glitter arrested over Savile affair – and other stars begin to worry

The pop star Gary Glitter has become the first person to be arrested by detectives investigating allegations of multiple sex attacks by the BBC presenter Jimmy Savile.

Thieves steal paintings worth £250m

Audacious thieves stole seven paintings worth a total of £250m from a Rotterdam museum in one of the biggest art raids in recent history.

Bookshops open early to launch JK Rowling's The Casual Vacancy

Bookshops opened their doors early today for readers to get their hands on JK Rowling's first novel for adults.

Everybody's talking about...An Incident At The Border

Trafalgar Studios 2, London

Further delays hit Tube services

Tube travellers suffered a series of hold-ups today - just days before the start of the Olympics.

Lack of sand caused train to overrun station

A runaway commuter train overshot a station by two-and-a-half miles because it did not have any sand on board to help with braking in poor weather.

'Cold case' rapist jailed

An unlicensed cab driver was jailed for five years at the Old Bailey today for raping a passenger nearly 17 years ago.

Sometimes I Laugh Like My Sister, Finborough Theatre, London

Rebecca Peyton describes the moment she knew her sister had died with this unholy, guttural noise from the back of her throat.

DVD: Mademoiselle Chambon (PG)

Any love story about pained longing at a train station will inevitably draw comparisons to classic David Lean/Noel Coward romance, Brief Encounter.

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Pompeii, Capri & the Bay of Naples
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Lake Garda
Minoan Crete and Santorini
Prices correct as of 17 April 2015
Arsenal vs Chelsea: Praise to Arsene Wenger for having the courage of his convictions

Michael Calvin's Last Word

Praise to Wenger for having the courage of his convictions
Major medical journal Lancet under attack for 'extremist hate propaganda' over its coverage of the Israeli-Palestinian conflict

Lancet accused of 'anti-Israel hate propaganda' over coverage of Gaza conflict

Threat to free speech as publishers of renowned medical journal are accused of inciting hatred and violence
General Election 2015: Tories and Lib Dems throw their star names west to grab votes

All noisy on the Lib Dems' western front

The party has deployed its big guns in Cornwall to save its seats there. Simon Usborne heads to the heart of the battle
How Etsy became a crafty little earner: The online market has been floated for £1.2bn, but can craft and capitalism coexist?

How Etsy became a crafty little earner

The online market has been floated for £1.2bn, but can craft and capitalism coexist?
Guy Ritchie is the latest filmmaker to tackle King Arthur - one of our most versatile heroes

King Arthur is inspiring Guy Ritchie

Raluca Radulescu explains why his many permutations - from folk hero to chick-lit hunk - never cease to fascinate
Apple Watch: Will it live up to expectations for the man or woman on the street?

Apple Watch: Will it live up to expectations?

The Apple Watch has apparently sold millions even before its launch tomorrow
Don't fear the artichoke: it's a good cook's staple, with more choice than you'd think

Don't fear the artichoke

Artichokes are scary - they've got spikes and hairy bits, and British cooks tend to give them a wide berth. But they're an essential and delicious part of Italian cuisine
11 best men's socks

11 best men's socks

Make a statement with your accessories, starting from the bottom up
Paul Scholes column: Eden Hazard would be my Player of the Year – but I wonder if he has that appetite for goals of Messi or Ronaldo

Paul Scholes column

Hazard would be my Player of the Year – but I wonder if he has that appetite for goals of Messi or Ronaldo
Frank Warren: Tyson Fury will be closely watching Wladimir Klitschko... when he wins it'll be time to do a deal

Frank Warren's Ringside

Tyson Fury will be closely watching Wladimir Klitschko... when he wins it'll be time to do a deal
London Marathon 2015: Kenya's brothers in arms Wilson Kipsang and Dennis Kimetto ready to take on world

Kenya's brothers in arms take on world

Last year Wilson Kipsang had his marathon record taken off him by training partner and friend Dennis Kimetto. They talk about facing off in the London Marathon
Natalie Bennett interview: I've lost track of the last time I saw my Dad but it's not because I refuse to fly

Natalie Bennett interview: I've lost track of the last time I saw my Dad

Green leader prefers to stay clear of her 'painful' family memories but is more open about 'utterly unreasonable' personal attacks
Syria conflict: Khorasan return with a fresh influx of fighters awaiting the order to start 'shooting the birds'

Khorasan is back in Syria

America said these al-Qaeda militants were bombed out of the country last year - but Kim Sengupta hears a different story
General Election 2015: Is William Cash the man to woo Warwickshire North for Ukip?

On the campaign trail with Ukip

Is William Cash the man to woo Warwickshire North?
Four rival Robin Hood movies get Hollywood go-head - and Friar Tuck will become a superhero

Expect a rush on men's tights

Studios line up four Robin Hoods productions