Life and Style Was the testosterone filled James Bond susceptible to bouts of man flu?

Men with high levels of testosterone have a secret flaw - less effective immune systems, researchers have discovered

A photo issued by Anthony Nolan trust of Gaurav Bains from Tipton in the West Midlands, with his mother Gurprit Bains

Joy for toddler Guarav's family as bone marrow match found after massive growth in Asian donors

Two-year-old boy had faced developing aggressive form of childhood leukaemia without transplant by Christmas

Researchers find ‘alarm’ that gives warning of recurring cancer

An alarm signal from the immune system offers an “invaluable” early warning of returning cancer, research has shown.

Steve Connor: The results so far arec good, but there's still a long way to go before an effective malaria vaccine is available

The vaccine known as "RTS,S", made by GlaxoSmithKline, was the first "candidate" vaccine against malaria and was initially developed as long ago as 1987. This fact alone indicates just how difficult and tortuous it is to manufacture a safe, reliable and effective vaccine against the malaria parasite.

Wenger believes Wilshere has the mentality of Zidane

Comment: Is Arsene Wenger right to be angry with Jack Wilshere for smoking?

Pictures have emerged that show the Arsenal midfielder holding a cigarette outside a nightclub

Scientists have discovered the 'blue print' for a revolutionary universal flu vaccine that could protect against all strains of seasonal inluenza – even new deadly new viruses never encountered before

Scientists discover 'blue print' for revolutionary universal flu vaccine

A set of naturally occurring immune cells could play a crucial role in the body's resistance to flu

Jordan's parliament in session

Jordanian MP opens fire on colleague with automatic gun after 'dispute about the budget'

Though debates can often get heated in the country's Chamber of Deputies, it is the first time in its history that bullets have been fired within the parliament building

Scientists discover what triggers allergic reactions to cats

Research conducted by a University of Cambridge team expands the possibility of creating preventative medicines

A standard syringe compared to the Nanopatch. Source: Vaxxas

New $1 patch can deliver vaccines without injections

Professor Mark Kendall's Nanopatch was shown off last night to crowds at TEDGlobal

Dad who joined bone marrow register when a friend became ill saves stranger's life just four weeks later

A dad who joined the bone marrow register when a friend became ill has become a match for someone else just weeks after she passed away.

The new vaccine could lead to broader immunity against new types of influenza viruses

Scientists create new flu vaccine that works against many different strains of the virus

New treatment developed by fusing key proteins of the virus with a bacterial protein

Agenda: John Newman; Julia Davis; wedding season; 10 O'Clock Live; New York-style dining

People, places, notes and observations...

Scientists develop nanoparticle method to help tackle major diseases

Scientists have developed a way of modifying a microscopic particle which could offer a new approach to tackling major diseases such as multiple sclerosis, Type 1 diabetes, asthma and food allergies.

Loud music on headphones causes deafness by having a similar effect on nerves as MS

Loud music played on earphones causes deafness by having a similar effect on nerves as multiple sclerosis (MS), scientists have learned.

Children risk asthma if parent of same sex has it

Children are twice as likely to develop allergic diseases including asthma if a parent of the same sex is a sufferer, new research suggests.

Many species of the poison dart frog are critically endangered

Rainforest wildlife havens on brink of collapse

Outside destruction is threatening lush reserves designed to protect world's richest biodiversity

Arts and Entertainment
The Doctor and Clara have their first real heart to heart since he regenerated in 'Deep Breath'
TV
Life and Style
Apple showed no sign of losing its talent for product launches with the new, slightly larger iPhone 6 making headlines
techSecurity breaches and overhyped start-ups dominated a year in which very little changed (save the size of your phone)
Arts and Entertainment
Jamie Oliver
filmTV chef Jamie Oliver turned down role in The Hobbit
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The official police photograph of Dustin Diamond taken after he was arrested in Wisconsin
peopleDownfall of the TV star charged with bar stabbing
Arts and Entertainment
Jeremy Clarkson, left, and Richard Hammond upset the locals in South America
tvReview: Top Gear team flee Patagonia as Christmas special reaches its climax in the style of Butch and Sundance
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people
Sport
Ashley Barnes of Burnley scores their second goal
footballMan City vs Burnley match report
Arts and Entertainment
Peter Mayhew as Chewbacca alongside Harrison Ford's Han Solo in 'Star Wars'
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Man of action: Christian Bale stars in Exodus: Gods and Kings
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Day In a Page

Independent Travel
Burgundy, the River Rhone & Provence – Five-star MS Swiss Corona 7 nights from £999pp
Lake Como St Moritz & the Bernina Express 7 nights from £809pp
Vietnam
Lake Maggiore, Orta & the Matterhorn 7 nights from £939pp
South Africa
Spain
Prices correct as of 19 December 2014
A timely reminder of the bloody anniversary we all forgot

A timely reminder of the bloody anniversary we all forgot

Who remembers that this week we enter the 150th anniversary year of the end of the American Civil War, asks Robert Fisk
Homeless Veterans appeal: Former soldiers pay their respects to a friend who also served

Homeless Veterans appeal

Former soldiers pay their respects to a friend who also served
Downfall of Dustin 'Screech' Diamond, the 'Saved By The Bell' star charged with bar stabbing

Scarred by the bell

The downfall of the TV star charged with bar stabbing
Why 2014 was a year of technological let-downs

Why 2014 was a year of technological let-downs

Security breaches and overhyped start-ups dominated a year in which very little changed (save the size of your phone)
Cuba's golf revolution: But will the revolutionary nation take 'bourgeois' game to its heart?

Will revolutionary Cuba take 'bourgeois' golf to its heart?

Fidel Castro ridiculed the game – but now investment in leisure resort projects is welcome
The Locked Room Mysteries: As a new collection of the genre’s best is published, its editor Otto Penzler explains the rules of engagement

The Locked Room Mysteries

As a new collection of the genre’s best is published, its editor explains the rules of engagement
Amy Adams on playing painter Margaret Keane in Tim Burton's Big Eyes

How I made myself Keane

Amy Adams hadn’t wanted to take the role of artist Margaret Keane, because she’d had enough of playing victims. But then she had a daughter, and saw the painter in a new light
Ed Richards: Parting view of Ofcom chief. . . we hate jokes on the disabled

Parting view of Ofcom chief... we hate jokes on the disabled

Bad language once got TV viewers irate, inciting calls to broadcasting switchboards. But now there is a worse offender, says retiring head of the media watchdog, Ed Richards
A look back at fashion in 2014: Wear in review

Wear in review

A look back at fashion in 2014
Ian Herbert: My 10 hopes for sport in 2015. Might just one of them happen?

Ian Herbert: My 10 hopes for sport in 2015

Might just one of them happen?
War with Isis: The West needs more than a White Knight

The West needs more than a White Knight

Despite billions spent on weapons, the US has not been able to counter Isis's gruesome tactics, says Patrick Cockburn
Return to Helmand: Private Davey Graham recalls the day he was shot by the Taliban

'The day I was shot by the Taliban'

Private Davey Graham was shot five times during an ambush in 2007 - it was the first, controversial photograph to show the dangers our soldiers faced in Helmand province
Revealed: the best and worst airlines for delays

Revealed: the best and worst airlines for delays

Many flyers are failing to claim compensation to which they are entitled, a new survey has found
The stories that defined 2014: From the Scottish independence referendum to the Ice Bucket Challenge, our writers voice their opinions

The stories that defined 2014

From the Scottish independence referendum to the Ice Bucket Challenge, our writers voice their opinions
Stoke-on-Trent becomes first British city to be classified as 'disaster resilient' by the United Nations

Disaster looming? Now you know where to head...

Which British city has become the first to be awarded special 'resilience' status by the UN?