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Francis Walsingham, who ran Elizabeth I’s secret service, built up a vast spy network to protect the Queen against the very real risk of assassination.

How C. difficile caused a seismic shift in health policy

The arrival of a virulent new strain of Clostridium difficile in Britain in the early 2000s caused a medical and political firestorm, led to hundreds of deaths and claimed the scalps of several NHS trust chief executives.

John Rentoul: The man who could have changed it all

Alan Johnson ducked his chance to be leader of his party, and David Cameron was the lucky beneficiary

John Rentoul: The shape of things to come

As the Lib Dems hold their ground, the Cameron and Brown camps must determine the price of victory

Two more 'in lobbying scandal'

Two more ex-Labour ministers were drawn into the lobbying scandal last night, after claims they had been secretly recorded offering to exploit government contacts to help business clients – for fees of up to £2,500 a day.

Geoff Hoon asked to relinquish Nato role

Former defence secretary Geoff Hoon was dropped from a Nato committee following his involvement in the lobbygate row, it emerged.

Nato asks Geoff Hoon to step down as policy expert

Geoff Hoon was yesterday asked to step down from his duties at Nato following his involvement in the "cash for access" scandal. Nato's secretary general, Anders Fogh Rasmussen, asked the former British Defence Secretary to withdraw from a group of 12 policy experts drafting the military alliance's new mission statement after he learnt of Mr Hoon's suspension from the Parliamentary Labour Party.

Simon Carr: Just another dark day in a very gloomy year for Hoon and Hewitt

Sketch: We are just in the foothills of shame, really. Onwards and upwards!

Harriet Harman denies ex-ministers influenced decisions

Commons leader Harriet Harman denied today that ministers had been influenced by the alleged lobbying of former Cabinet ministers into making improper decisions.

Andrew Grice: Labour madness over lobbying scandal

Some "friends" of Gordon Brown are putting it about that he won't really be damaged much by the lobbying allegations against Stephen Byers, Patricia Hewitt and Geoff Hoon because the three former Cabinet ministers are Blairites.

Yasmin Alibhai-Brown: The future of politics lies with women

The leaders are trying to charm us with vacuous words and meaningless policies

Ministers furious at new lobbying 'scandal'

Byers, Hewitt and Hoon face sleaze inquiry over 'cash-for-access' allegations

Blairite star Purnell quits as MP

As Labour unveils ‘A future fair for all’ campaign slogan, former minister tipped as future leader shocks party

Ex-minister Hoon to stand down as MP

Former defence secretary Geoff Hoon is to stand down from Parliament at the election this year, it was announced today.

John Rentoul: The biggest loser from this election will be positive politics

We are in the run-up to an anti-politics election. It is a dismal, life-denying prospect

Labour MPs rally behind Brown after plot

Gordon Brown drew the final line under the failed backbench coup against him by declaring last night that Britain's "hard-won economic recovery" could still be Labour's platform for election victory.

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Pompeii, Capri & the Bay of Naples
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Burgundy, the River Rhone & Provence
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Lake Garda
Minoan Crete and Santorini
Prices correct as of 15 May 2015
Sepp Blatter resignation: The beginning of Fifa's long road to reform?

Does Blatter's departure mean Fifa will automatically clean up its act?

Don't bet on it, says Tom Peck
Charles Kennedy: The baby of the House who grew into a Lib Dem giant

The baby of the House who grew into a Lib Dem giant

Charles Kennedy was consistently a man of the centre-left, dedicated to social justice, but was also a champion of liberty and an opponent of the nanny-state, says Baroness Williams
Syria civil war: The harrowing testament of a five-year-old victim of this endless conflict

The harrowing testament of a five-year-old victim of Syria's endless civil war

Sahar Qanbar lost her mother and brother as civilians and government soldiers fought side by side after being surrounded by brutal Islamist fighters. Robert Fisk visited her
The future of songwriting: How streaming is changing everything we know about making music

The future of songwriting

How streaming is changing everything we know about making music
William Shemin and Henry Johnson: Jewish and black soldiers receive World War I Medal of Honor amid claims of discrimination

Recognition at long last

Jewish and black soldiers who fought in WWI finally receive medals after claims of discrimination
Beating obesity: The new pacemaker which helps over-eaters

Beating obesity

The new pacemaker which helps over-eaters
9 best women's festival waterproofs

Ready for rain: 9 best women's festival waterproofs

These are the macs to keep your denim dry and your hair frizz-free(ish)
Cycling World Hour Record: Nervous Sir Bradley Wiggins ready for pain as he prepares to go distance

Wiggins worried

Nervous Sir Bradley ready for pain as he prepares to attempt cycling's World Hour Record
Liverpool close in on Milner signing

Liverpool close in on Milner signing

Reds baulk at Christian Benteke £32.5m release clause
On your feet! Spending at least two hours a day standing reduces the risk of heart attacks, cancer and diabetes, according to new research

On your feet!

Spending half the day standing 'reduces risk of heart attacks and cancer'
With scores of surgeries closing, what hope is there for the David Cameron's promise of 5,000 more GPs and a 24/7 NHS?

The big NHS question

Why are there so few new GPs when so many want to study medicine?
Big knickers are back: Thongs ain't what they used to be

Thongs ain't what they used to be

Big knickers are back
Thurston Moore interview

Thurston Moore interview

On living in London, Sonic Youth and musical memoirs
In full bloom

In full bloom

Floral print womenswear
From leading man to Elephant Man, Bradley Cooper is terrific

From leading man to Elephant Man

Bradley Cooper is terrific