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Shire has made its biggest acquisition, spending $4.2bn (£2.6bn) on the US drugs maker ViroPharma. Shares in Shire rose 26p to 2,822p, even though it paid $50 a share for the rare-diseases specialist, which had revenues of $428m last year. Shire’s chief executive Flemming Ornskov expects to create $2bn revenues from medicines for rare diseases next year.

Doesn’t suit you, sir: Alan Lewis loses Nutter brand

A high court row over the rights to use a famous 1960s Savile Row tailoring brand has been lost by Conservative Party vice-chairman Alan Lewis.

The Business Matrix: Tuesday 8 October 2013

BP may face fines of $18bn over spill

What the Sunday papers said

The Business Matrix: Monday 7 October 2013

Hastings Direct pulls in Goldman

The Great British Sewing Bee

Great British Sewing Bee to return for six-part second series

The Great British Sewing Bee will return for a second longer series, BBC Two has confirmed.

The Business Matrix: Friday 5 April 2013

Debenhams signs Sewing Bee's Grant

Matt Prior’s rapid 82 has put England in a commanding position

New Zealand v England: Me the greatest? Not just yet, insists Matt Prior

Prior struck an outstanding innings of 82

A model at Zoe Jordan’s show, which was the first at this year’s London Fashion Week

Go! Go! Go! F1 mogul’s daughter, Zoe Jordan, hits catwalk

The British Fashion Council turns 30 this year, and with new chairman Natalie Massenet installed, it seems the organisation - and London fashion itself - is in rude health.

J.W. Anderson creations are presented at the London Collections: Men yesterday

Scots invade the catwalk as men's designers enjoy a final fling in London

Lambswool and tartan featured as fashion week wraps up

Spooky-couture: the fashion show from hell, via Fantich & Young

If Satan sported Oxford Shoes, they'd probably look something like this - that is, polished enough to reflect the sufferings of the damned, with 1,050 teeth grafted into the soles for good measure. The shoes, pictured above, are included in a collection of nightmarish objects by designers Fantich and Young. Interested in spooky-couture? Look no further.

Hello chaps, welcome to the club: Stores embrace the silent revolution in menswear

Menswear stores are bringing out the big guns in their battle with online retailers – and that means on-site barber shops and billiards tables

9 Savile Row, London W1

Tailor made: Alexander McQueen comes to Savile Row

Alexander McQueen may be the newest name above a Savile Row shop front, but it marks a welcome return to the label's roots, says Rebecca Gonsalves

The Fashion Audit: Varsity blues, dangerous nails and Marios Schwab

What we love, we're not sure about, we're buying and can't wait for...

Prince Charles joked last night that it has taken him 64 years to attain fashion icon status

The new king of fashion entertains his subjects...

London's first men's fashion week kicked off last night with a party hosted by an unlikely new style icon

Prince Charles sporting his polo look

The Prince of Wales: A new name in fashion royalty

Depending on your republican leanings, it could be argued that the British Monarchy represents both the best and worst of the country. So perhaps it's fitting that although the Prince of Wales was recently named as one of GQ's best-dressed men, he has featured on worst-dressed lists. But that hasn't stopped his odd ascent to the top of British fashion.

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Orthorexia nervosa: How becoming obsessed with healthy eating can lead to malnutrition

Orthorexia nervosa

How becoming obsessed with healthy eating can lead to malnutrition
Lady Chatterley is not obscene, says TV director

Lady Chatterley’s Lover

Director Jed Mercurio on why DH Lawrence's novel 'is not an obscene story'
Farmers in tropical forests are training ants to kill off bigger pests

Set a pest to catch a pest

Farmers in tropical forests are training ants to kill off bigger pests
Mexico: A culture that celebrates darkness as an essential part of life

The dark side of Mexico

A culture that celebrates darkness as an essential part of life
Being sexually assaulted was not your fault, Chrissie Hynde. Don't tell other victims it was theirs

Being sexually assaulted was not your fault, Chrissie Hynde

Please don't tell other victims it was theirs
A nap a day could save your life - and here's why

A nap a day could save your life

A midday nap is 'associated with reduced blood pressure'
If men are so obsessed by sex, why do they clam up when confronted with the grisly realities?

If men are so obsessed by sex...

...why do they clam up when confronted with the grisly realities?
The comedy titans of Avalon on their attempt to save BBC3

Jon Thoday and Richard Allen-Turner

The comedy titans of Avalon on their attempt to save BBC3
The bathing machine is back... but with a difference

Rolling in the deep

The bathing machine is back but with a difference
Part-privatised tests, new age limits, driverless cars: Tories plot motoring revolution

Conservatives plot a motoring revolution

Draft report reveals biggest reform to regulations since driving test introduced in 1935
The Silk Roads that trace civilisation: Long before the West rose to power, Asian pathways were connecting peoples and places

The Silk Roads that trace civilisation

Long before the West rose to power, Asian pathways were connecting peoples and places
House of Lords: Outcry as donors, fixers and MPs caught up in expenses scandal are ennobled

The honours that shame Britain

Outcry as donors, fixers and MPs caught up in expenses scandal are ennobled
When it comes to street harassment, we need to talk about race

'When it comes to street harassment, we need to talk about race'

Why are black men living the stereotypes and why are we letting them get away with it?
International Tap Festival: Forget Fred Astaire and Ginger Rogers - this dancing is improvised, spontaneous and rhythmic

International Tap Festival comes to the UK

Forget Fred Astaire and Ginger Rogers - this dancing is improvised, spontaneous and rhythmic
War with Isis: Is Turkey's buffer zone in Syria a matter of self-defence – or just anti-Kurd?

Turkey's buffer zone in Syria: self-defence – or just anti-Kurd?

Ankara accused of exacerbating racial division by allowing Turkmen minority to cross the border