News A mosquito waiting to be studied - scientists have identified the changes to the genes of the malaria parasite that make it resistant to one of the last effective drugs

Discovery of genes that confer resistance to the drug artemisinin is major step forward for treatment of the disease

Steve Connor: The results so far arec good, but there's still a long way to go before an effective malaria vaccine is available

The vaccine known as "RTS,S", made by GlaxoSmithKline, was the first "candidate" vaccine against malaria and was initially developed as long ago as 1987. This fact alone indicates just how difficult and tortuous it is to manufacture a safe, reliable and effective vaccine against the malaria parasite.

World's first malaria vaccine which could be available from 2015 should not be viewed as a silver bullet against the disease, say scientists

British drug company GlaxoSmithKline seeking regulatory approval for vaccine to prevent disease which kills around 660,000 people every year

There is no risk of bats helping to spread malaria to people

Bat 'immunity' over malaria parasites could could be key to human vaccines, says top scientist

The bugs have probably infected bats for millions of years and their immune system has evolved to cope

How nets save lives: UK pledges £1bn to battle Malaria and other preventable diseases

To think that every minute, a parent somewhere loses their son or daughter to malaria because of a mosquito bite is heart-wrenching

Boxer Herbie Hide fails to attend drugs trial

The former world champion boxer Herbie Hide is facing arrest after he failed to attend court on drug charges, saying he was suffering from malaria in a Nigerian clinic.

Alex Turner and Co rose to the occasion and gave the kind of performance that justified their choice as headliners

Glastonbury festival first night review: Superb Arctic Monkeys put on incredible show

The beauty of the Pilton pop festival is that there’s always something to pull you from the main drag

Doctors observe patients suffering from dengue fever during an outbreak of the virus in Jakarta, Indonesia, in 2005. The disease is common in Asia

Singapore on alert after dengue fever cases rise

More than 9,000 people have contracted the mosquito-borne disease since January

Normandy Voices: Driver Mechanic Gordon Hornsby

Mr Hornsby drove a series of ambulances from Normandy to the Netherlands

Milan’s Kevin-Prince Boateng gestures towards his abusers

Run for Your Wife - 'As funny as leprosy'

Ray Cooney's film about a bigamist taxi driver gets a vicious mauling from the critics

Portfolio: The nature detectives

Imagine standing on the surface of the Moon, staring back at Earth and having in your grasp a device that allows you to see a tennis ball.

Sir Ronald Ross

Never before seen letters reveal the story of the scientist who laid the foundations of a cure for malaria more than a century ago

When British doctor Sir Ronald Ross discovered the crucial link between mosquitos and malaria at the end of the 19 century, he understandably thought it marked the beginning of the end of the deadly disease – rampant then not only in colonial India and Africa, but also in southern European countries such as Greece and Italy.

Malaria deaths twice as high as was thought

Malaria is killing almost twice as many people around the world than was previously thought, a study has shown.

Wallace and Gromit creators in leprosy row

The creators of Wallace and Gromit and Chicken Run are at the centre of an angry storm surrounding their latest film amid accusations of bad taste and disability discrimination.

Funding threat to Pakistan flood relief

Western aid agencies in Pakistan warned yesterday that they might have to halt flood relief efforts in the cash-strapped country because of funding shortfalls.

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Independent Travel
Burgundy, the River Rhone & Provence – Five-star MS Swiss Corona 7 nights from £999pp
Lake Como St Moritz & the Bernina Express 7 nights from £809pp
Vietnam
Lake Maggiore, Orta & the Matterhorn 7 nights from £939pp
South Africa
Spain
Prices correct as of 19 December 2014
Homeless Veterans appeal: 'You look for someone who's an inspiration and try to be like them'

Homeless Veterans appeal

In 2010, Sgt Gary Jamieson stepped on an IED in Afghanistan and lost his legs and an arm. He reveals what, and who, helped him to make a remarkable recovery
Could cannabis oil reverse the effects of cancer?

Could cannabis oil reverse effects of cancer?

As a film following six patients receiving the controversial treatment is released, Kate Hilpern uncovers a very slippery issue
The Interview movie review: You can't see Seth Rogen and James Franco's Kim Jong Un assassination film, but you can read about it here

The Interview movie review

You can't see Seth Rogen and James Franco's Kim Jong Un assassination film, but you can read about it here
Serial mania has propelled podcasts into the cultural mainstream

How podcasts became mainstream

People have consumed gripping armchair investigation Serial with a relish typically reserved for box-set binges
Jesus Christ has become an unlikely pin-up for hipster marketing companies

Jesus Christ has become an unlikely pin-up

Kevin Lee Light, aka "Jesus", is the newest client of creative agency Mother while rival agency Anomaly has launched Sexy Jesus, depicting the Messiah in a series of Athena-style poses
Rosetta space mission voted most important scientific breakthrough of 2014

A memorable year for science – if not for mice

The most important scientific breakthroughs of 2014
Christmas cocktails to make you merry: From eggnog to Brown Betty and Rum Bumpo

Christmas cocktails to make you merry

Mulled wine is an essential seasonal treat. But now drinkers are rediscovering other traditional festive tipples. Angela Clutton raises a glass to Christmas cocktails
5 best activity trackers

Fitness technology: 5 best activity trackers

Up the ante in your regimen and change the habits of a lifetime with this wearable tech
Paul Scholes column: It's a little-known fact, but I have played one of the seven dwarves

Paul Scholes column

It's a little-known fact, but I have played one of the seven dwarves
Fifa's travelling circus once again steals limelight from real stars

Fifa's travelling circus once again steals limelight from real stars

Club World Cup kicked into the long grass by the continued farce surrounding Blatter, Garcia, Russia and Qatar
Frank Warren column: 2014 – boxing is back and winning new fans

Frank Warren: Boxing is back and winning new fans

2014 proves it's now one of sport's biggest hitters again
Jeb Bush vs Hillary Clinton: The power dynamics of the two first families

Jeb Bush vs Hillary Clinton

Karen Tumulty explores the power dynamics of the two first families
Stockholm is rivalling Silicon Valley with a hotbed of technology start-ups

Stockholm is rivalling Silicon Valley

The Swedish capital is home to two of the most popular video games in the world, as well as thousands of technology start-ups worth hundreds of millions of pounds – and it's all happened since 2009
Did Japanese workers really get their symbols mixed up and display Santa on a crucifix?

Crucified Santa: Urban myth refuses to die

The story goes that Japanese store workers created a life-size effigy of a smiling "Father Kurisumasu" attached to a facsimile of Our Lord's final instrument of torture
Jennifer Saunders and Kate Moss join David Walliams on set for TV adaptation of The Boy in the Dress

The Boy in the Dress: On set with the stars

Walliams' story about a boy who goes to school in a dress will be shown this Christmas