Middlesbrough vs Liverpool live: Latest score and updates plus what time does it start, what TV channel is it on?

Follow live updates from the Premier League fixture at the Riverside

Loris Karius will once again be under close scrutiny after a number of mistakes for Liverpool (Getty)

Loris Karius has lost his place in Liverpool’s starting line-up ahead of Wednesday’s trip to Middlesbrough.

The under-fire goalkeeper will be replaced by Simon Mignolet after his mistakes costs points against both Bournemouth and West Ham United.

Aitor Karanka’s men are the Premier League’s lowest scorers and will hope to bounce back from Sunday’s defeat at Southampton.

Kick-off: 7.45pm

Wednesday's Premier League fixtures

• Middlesbrough vs Liverpool (7.45pm)
• Sunderland vs Chelsea (7.45pm)
• West Ham United vs Burnley (7.45pm)
• Crystal Palace vs Manchester United  (8.00pm)
• Manchester City vs Watford (8.00pm)
• Stoke City vs Southampton (8.00pm)
• Tottenham Hotspur vs Hull City (8.00pm)
• West Bromwich Albion vs Swansea City (8.00pm)

Follow live updates on the blog below...

Scroll through the scoreboard to see the latest scores from Wednesday's other matches

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It’s a big game for…

LORIS KARIUS: The German goalkeeper has struggled to keep out of the headlines of late after a number of high profile mistakes and verbal sparring with television pundits. However, here he has the chance to put that business behind him and get Liverpool back to winning ways.

Weird /best stat…

7: Middlesbrough are unbeaten in seven Premier League home matches against Liverpool since a 2-1 defeat in March 2002 (W3, D4).

Remember when…

Liverpool 2 Middlesbrough 2 (14-13 pens) Capital One Cup Third Round 2014

Both teams needed 120 minutes and 28 penalty kicks to separate them but, after Suso dispatched his decisive spot kick for Liverpool, Albert Adomah blazed his effort high and wide to send the Reds through to the fourth round.

Player to watch…

Gaston Ramirez: The Uruguayan is having an impressive season on his return to the Premier League with Boro and could cause a shaky Liverpool defence big problems at the Riverside. His cohesive partnership with Alvaro Negredo gives the home side a real threat going forward.

Past three-meetings…

LIVERPOOL 2 (Rossiter, Fernandez Saez) MIDDLESBROUGH 2 (Reach, Bamford) (14-13 pens), September 2014

MIDDLESBROUGH 2 (Alonso OG, Tuncay Sanli) LIVERPOOL 0, February 2009

LIVERPOOL 2 (Pogatetz OG, Gerrard) MIDDLESBROUGH 1 (Mido), August 2008

Form guide…

MIDDLESBROUGH: LWDLDW

LIVERPOOL: DLWWDW

Vital information…

KICK-OFF TIME: 7:45

TV: Highlights on BBC One at 10:45

[14 December 2016 19:32 · Sam Dymond]

After Arsenal faltered on Merseyside last night, North London rivals Tottenham can close the gap on their neighbours to four points with a win at home to Hull City. History, it would seem, is on their side.

[14 December 2016 19:42 · Sam Dymond]

Congratulations to the fiercest hand-shaker in the Premier League.

Although I'm sure he'd choose to erase any trace of those 30-odd games in charge of QPR.

[14 December 2016 19:44 · Sam Dymond]

It's almost time for the off in the first batch of tonight's Premier League games...

[14 December 2016 19:47 · Sam Dymond]

KICK-OFF: The Premier League is go! We are off at the Riverside Stadium, the Stadium of Light and whatever that soulless place that West Ham play at is called.

[14 December 2016 19:53 · Sam Dymond]

The London Stadium, apparently.

[14 December 2016 20:00 · Sam Dymond]

Supporters were advised to turn up early at the Riverside Stadium to avoid queues.

[14 December 2016 20:01 · Sam Dymond]

KICK-OFF: And now the other five games are underway! News of all the goals, LOLS and bellyaches will be with you as soon as they happen.

[14 December 2016 20:07 · Sam Dymond]

5 mins: Crystal Palace 0 Manchester United 0: Rooney has his first attempt of the evening as he goes searching for the goal to equal Bobby Charlton's United goalscoring record. The England captain has just headed over Juan Mata's cross.

Meanwhile, Eric Bailly has gone down injured off the ball and looks in some discomfort. Matteo Darmian is warming up on the touchline and ready to replace him if necessary.

[14 December 2016 20:11 · Sam Dymond]

I bet this account never tweeted these words when Tony Pulis was in charge.

[14 December 2016 20:13 · Sam Dymond]

No Premier League goals at the moment to report, but Newcastle - with their bottom half of the Premier League players on top half of the Premier League wages - are a goal up at Wigan in the Championship. Expect to see them back in the top flight soon.