Manuwa headlined last year’s London fight card and recorded something of a statement victory, stopping The Ultimate Fighter 19 winner Corey Anderson with a vicious first-round knockout.
The dominant performance thrust Manuwa, 37, into title contention, but he lost his next contest to Switzerland’s Volkan Oezdemir in just 42-seconds, a surprise result that saw him slip back down to fourth in the light-heavyweight rankings.
However, a second victory over Blachowicz – whom Manuwa defeated via unanimous decision back in April 2015 – will likely see him climb over Glover Teixeira and back into title contention.
“Jan is the only person I’ve ever been the distance with,” Manuwa recently remarked of his next opponent. “I feel I did dominate him in that fight, and I felt he was running a lot. At the same time, I feel Jan has got a lot better and I’ve got a lot better.
“I think it makes for an interesting fight. He looked really good in his last fight and that’s the main reason why I accepted it.”
Manuwa isn’t the only home favourite set to feature on March 17.
“I’m going to London and I’m going to put this guy away,” Edwards said at the beginning of the year. “After that they can’t deny me a ranked opponent.”
Also on the card is Scottish heavyweight Paul Craig, who will be looking to bounce back from consecutive defeats when he takes on the undefeated Dagestani prospect Magomed Ankalaev.
Who’s going to headline?
The big boys will take centre stage at the O2 on Saturday evening.
Former UFC heavyweight world champion Fabrício Werdum takes on former Bellator heavyweight world champion Alexander Volkov. Expect fireworks.
When are tickets going to go on sale?
Tickets went on general sale at the beginning of February.
There are some still available on StubHub, but prices begin at a cool £60.
Join our new commenting forum
Join thought-provoking conversations, follow other Independent readers and see their replies