He dedicated his song 'The Promised Land' to Renee Good, an American citizen fatally shot by an ICE officer in Minneapolis on 7 January.
Springsteen condemned the use of 'Gestapo tactics' by heavily-armed federal troops and asserted that no one should be murdered for exercising their right to protest.
He echoed Minneapolis Mayor Jacob Frey's demand for ICE to 'get the f*** out' of the city, following the shooting and ongoing immigration enforcement operations.
Other celebrities, including actor Mark Ruffalo, have also protested the administration, with many wearing 'BE GOOD' and 'ICE OUT' buttons at events like the Golden Globe Awards.