Fox's hit animated series Family Guy is set to air its 450th episode and season 24 premiere on Sunday at 9:30 p.m. ET.
The premiere episode will feature Lois and Stewie understanding each other for the first time, thanks to Brian's edibles, as they explore their complex relationship.
Upcoming storylines for season 24 include Peter and the guys getting shipwrecked, Chris and Brian performing a lobotomy on Stewie and Lois and Meg's criminal obsession with pumpkin spice lattes.
Created by Seth MacFarlane in 1999, the show, known for its controversial humor, was previously cancelled twice before being revived due to strong DVD sales and Adult Swim reruns.
Despite declining traditional TV viewership, the series has endured for over two decades, with its humor evolving to become more self-aware and its animation improving.
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