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Warning signs for Parkinson’s disease could be found in the mouth

Scientists link gut bacteria to early stages of Parkinson’s disease
  • New research suggests that changes in oral and gut bacteria in Parkinson's disease patients could serve as an early warning sign of worsening symptoms.
  • Scientists used artificial intelligence (AI) to link specific bacterial changes to cognitive decline, including memory and learning problems, in Parkinson's patients.
  • The study, led by King's College London, analysed spit and stool samples from Parkinson's patients with mild cognitive impairment and dementia, as well as healthy individuals, finding more harmful bacteria in the guts of those with cognitive impairment.
  • Researchers identified toxins released by these bacteria that can damage gut tissue, promote inflammation, and potentially affect the brain, suggesting these toxins could be used as markers to identify Parkinson's patients at higher risk of developing dementia.
  • The study indicates that maintaining oral and gut health through consistent oral care, a balanced diet, and targeted probiotic interventions could improve disease management in Parkinson's, potentially slowing neurodegenerative processes.
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