The ‘youth molecule’ that protects against Alzheimer’s and Parkinson’s
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A global review highlights the critical role of the molecule NAD+ in slowing ageing and protecting against diseases like Alzheimer’s and Parkinson’s.
NAD+, often called the “youth molecule”, is essential for cellular function, DNA repair, and energy production, but its levels naturally decline with age, contributing to age-related issues.
Early clinical trials using NAD+ precursor molecules, such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), show encouraging improvements in memory, movement, and metabolism.
Despite a booming commercial market for NAD+ supplements, researchers note confusion regarding their effectiveness and the translation of animal study results to humans.
Scientists are calling for larger, longer-term clinical studies to determine optimal doses, administration methods, long-term safety, and individual responses to NAD+ augmentation strategies.