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Drugs used to relieve allergies may harm our brains in the long run

Over-the-counter antihistamines, commonly used for allergies, colds, and sleep, may increase the risk of dementia
Over-the-counter antihistamines, commonly used for allergies, colds, and sleep, may increase the risk of dementia (Getty/iStock)
  • Over-the-counter antihistamines, commonly used for allergies, colds, and sleep, may increase the risk of dementia, according to recent studies.
  • First-generation antihistamines, like Benadryl, more easily cross the blood-brain barrier and impact acetylcholine, a key brain chemical for memory, posing a higher risk compared to second-generation options.
  • A 2023 study in the Journal of Alzheimer's Disease linked frequent use of first-generation antihistamines to an increased risk of dementia in older adults.
  • Dr Pamela Tambini advises caution with over-the-counter antihistamines, noting they can impair thinking and potentially lead to long-term cognitive issues, especially in older adults.
  • Doctors recommend exploring newer antihistamine options like Claritin and consulting with a healthcare provider to determine the safest and most effective treatment.
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