This long-term follow-up study suggests that the significant improvements in depression symptoms observed after one year continued to hold strong, potentially lasting longer than traditional treatments.
Participants in the original study received two doses of psilocybin, found in magic mushrooms, alongside 13 hours of psychotherapy support.
Researchers have acknowledged the studies’ limitations, including the absence of a comparison group, the use of antidepressants by some participants, and the lack of a placebo in the initial trial.
Despite methodological challenges, the findings suggest lasting benefits from just one or two treatment sessions, potentially by triggering positive behavioural feedback loops and fostering personality changes.