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Magic mushroom therapy could provide lasting depression treatment for years

The Conversation Original report by Petri Kajonius
Related: Magic Mushrooms could lengthen your lifespan
  • Research from Ohio State University and Johns Hopkins University indicates that two-thirds of individuals who underwent psilocybin-assisted therapy remained free from depression five years later.
  • This long-term follow-up study suggests that the significant improvements in depression symptoms observed after one year continued to hold strong, potentially lasting longer than traditional treatments.
  • Participants in the original study received two doses of psilocybin, found in magic mushrooms, alongside 13 hours of psychotherapy support.
  • Researchers have acknowledged the studies’ limitations, including the absence of a comparison group, the use of antidepressants by some participants, and the lack of a placebo in the initial trial.
  • Despite methodological challenges, the findings suggest lasting benefits from just one or two treatment sessions, potentially by triggering positive behavioural feedback loops and fostering personality changes.
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