A study published in Nature Medicine utilised a new AI platform, BioMapAI, to analyse gut bacteria, immune responses, and metabolism from 249 individuals, achieving 90 per cent accuracy in distinguishing ME/CFS patients.
The research revealed that individuals with chronic fatigue had lower levels of butyrate, a beneficial fatty acid, and other nutrients crucial for metabolism and energy.
While immune cell analysis proved most accurate for predicting symptom severity, gut bacteria data helped predict emotional symptoms and sleep disturbances, indicating biological dysregulation.
This breakthrough offers hope for developing precise diagnostic tools and treatments for ME/CFS, a condition affecting an estimated 404,000 people in the UK, with similar symptoms seen in many long Covid sufferers.