Dramatic footage showed the aircraft losing control mid-air, spiralling before it crashed into palm trees and became wedged near a pedestrian bridge.
The injured include two individuals who were on board the helicopter and three people on the street, one of whom is a child.
The helicopter was reportedly linked to an annual 'Cars 'N Copters' fundraising event scheduled for Sunday.
The cause of the crash is currently unknown, with the Federal Aviation Administration and National Transportation Safety Board notified to investigate.