How hidden infections could make long Covid even worse
Related: ‘Long Covid forced me to quit the job I loved’
Long Covid affects approximately 400 million people globally, with its underlying cause remaining unknown despite a wide range of debilitating symptoms.
A group of leading microbiologists suggests that persistent Long Covid symptoms may stem from additional infections acquired before or during SARS-CoV-2 infection.
A review in eLife highlights Epstein-Barr virus (EBV) and Tuberculosis (TB) as potential co-infections, which could be reactivated by Covid-19's impact on the immune system.
Studies indicate that a significant number of Long Covid patients show signs of recent EBV activity, linking its reactivation to common symptoms like fatigue and cognitive problems.
While researchers propose repurposing antibiotics and antivirals to target these underlying infections, they emphasise that this remains a speculative hypothesis, and a causal link has not yet been established.