Scientists may have found a way to stop the ‘silent killer’
Alex Trebek in Global PSA for World Pancreatic Cancer Day
Researchers in Germany have potentially discovered how pancreatic cancer, often called the 'silent killer', hides from the immune system.
The study identified that the MYC cancer gene not only promotes tumour growth but also camouflages tumours by suppressing alarm signals that would normally activate the immune system.
Blocking this MYC mechanism in animals led to a dramatic 94 per cent reduction in tumour size, provided the animals' immune systems were intact.
This breakthrough suggests new therapeutic avenues to make tumours visible and vulnerable to the body's own defences without harming healthy cells.
The findings are expected to inform the development of new treatments for MYC-driven cancers, including childhood solid tumours, and enhance existing cancer therapies.