Both pharmaceutical companies are actively investigating and testing these drugs for a broader range of medical conditions beyond their current uses for diabetes and weight loss.
New conditions under exploration include alcohol use disorder, Alzheimer's disease, heart failure, chronic kidney disease, and a type of fatty liver disease called non-alcoholic steatohepatitis.
Significant developments include Ozempic's US approval for reducing kidney failure risk in diabetes patients and Zepbound's US approval for obstructive sleep apnea in December 2024.
Novo Nordisk has indicated that increased competition and the emergence of copycat versions are expected to affect Wegovy sales this year.