The world No 2 was unable to register for the tournament in Wigan due to being stuck in traffic.
This absence means Littler misses one of the final two opportunities for players to secure their spots in the season-ending Players Championship finals in Minehead.
Littler had recently boosted his qualification hopes for the finals with a victory at Players Championship 32 earlier this month.
He made light of the situation on social media, stating he intended to go “back to bed”.