Up to 3in (8cm) of snow could fall in parts of the UK tomorrow as the big freeze continues.
Forecasters have warned of dangerous conditions on the nation's roads caused by freezing rain.
The latest treacherous weather comes after three people died in sub-zero, icy conditions in the north of England this week.
Nick Prebble, forecaster for MeteoGroup, the weather division of the Press Association, said: "There will be a problem with freezing rain in the morning which is going to start causing problems in southern Scotland and northern England.
"It will spread south east, and as it moves will turn into sleet and snow."
The cold front will move to North Wales and Yorkshire, hitting the Midlands by the middle of tomorrow afternoon, he added.
Mr Prebble said: "From midday onwards, there will be snow falling, with between 4cm (1.6in) and 8cm (3in) possible.
"The areas worst affected are likely to be East Yorkshire, Lincolnshire and the East Midlands.
"There may well be snow flurries in London by the evening.
"It looks like it is going to settle in quite a wide area."
Sub-zero temperatures are set to continue for much of the UK over the coming days, with the mercury struggling to get above 0C (32F).
Temperatures reached minus 12C (10.4F) in Church Fenton, North Yorkshire, on Tuesday night but are not due to be as low this evening, with the Midlands set to experience the coldest conditions, of around minus 7C (19.4F).
Mr Prebble added: "At the weekend and next week it won't be as bitterly cold, but it is certainly still going to feel very chilly."
The Met Office has issued a level-three severe cold weather alert lasting until Saturday and has warned of icy roads across much of the UK.
Drivers have been reminded that roads will still pose a risk even if the temperatures begin to warm.
The thick blanket of snow that fell over parts of the UK at the weekend caused major travel disruption with a spike in road crashes and breakdowns.
A handful of schools were also forced to close due to the adverse weather conditions, while Heathrow Airport axed half of all flights on Sunday night.
Award-winning cheese-maker Mandy Reed was found dead in a snowy garden near her home on the edge of the Yorkshire Dales in the early hours of Sunday morning. The 47-year-old's death is being investigated by police.
In Hull, a man believed to be in his 50s was found dead in a park earlier this week. Police were called to an area near Woodland Road on Monday morning after the body was found by a dog walker.
He is thought to have frozen to death in temperatures which hit minus 7C (19.4F) in Hull on Sunday night.
In Castleford, West Yorkshire, a 10-year-old boy was found collapsed outside a friend's house on Sunday after going out to play in the snow.
Joshua Houlgate, who is understood to have suffered from epilepsy when he was younger, was pronounced dead in hospital despite frantic efforts to save him at the scene.