Autism signs in fish 'astonishing'
Thursday 07 June 2012
Signs of autism have been found in fish swimming in water contaminated with psychoactive medications.
Scientists identified patterns of gene activity in the fathead minnows that mimicked those seen in susceptible humans with the developmental disorder.
The findings suggest a potential environmental trigger for autism in genetically vulnerable people, the study authors said.
Researchers from Idaho State University in the US exposed fish to the antidepressant Prozac (fluoxetine) and two other chemicals. These were venlafaxine, another antidepressant, and carbamazepine, used to control seizures.
Concentrations were comparable with the highest estimated environmental levels.
The genetic pathways affected were the same as those associated with "idiopathic" autism spectrum disorders whose cause is unknown.
Experts suspect the disorders were brought about by a combination of genetic and environmental factors.
The new findings are published in the online journal Public Library of Science ONE.
Lead scientist Dr Michael Thomas said: "While others have envisioned a causal role for psychotropic drugs in idiopathic autism, we were astonished to find evidence that this might occur at very low dosages, such as those found in aquatic systems."
Is your name now 'banned' in Saudi Arabia?
Seth Rogen compiles list of all the celebrities he’s got high with
Oscar Pistorius trial: Photographs of Paralympian splattered in blood after Reeva Steenkamp shooting shown in court
Missing Malaysia Airlines Flight MH370: Satellite ‘pings sent five hours after contact was lost' the only clue in hunt for £160m plane
Missing Malaysia Airlines Flight MH370: New radar evidence suggests missing plane may have been hijacked
Katie Hopkins continues campaign to become Britain's most hated talking head with poorly timed Bob Crow tweet
No EU referendum under Labour: Ed Miliband to reveal that vote on membership is ‘unlikely’ in next Parliament if party wins power
Grace Dent: Who cares if she spells it Barraco Barner? Gemma Worrall is more employable than some bookish arts graduate
Europeans have ‘got whiter’ due to natural selection in past 5,000 years, scientists say
Fracking is turning the US into a bigger oil producer than Saudi Arabia
The rise of Ukip: Study warns Labour that Eurosceptic party's electoral base now 'more working class than any of the main parties'
- 1 Is your name now 'banned' in Saudi Arabia?
- 2 Best films on Netflix: 32 movies that will put an end to your scrolling
- 3 Istanbul protesters take 'Ellen selfie' from the back of a police van
- 4 Missing Malaysia Airlines Flight MH370: Jet ‘hi-jacking’ began soon after take-off
- 5 Lady Gaga has struggled with eating disorders in the past, so it's indefensible that she's glamourising bulimia in her SXSW set
£50000 - £60000 per annum: Charter Selection: This well respected and exciting...
£40000 - £50000 per annum: Charter Selection: This exciting company and market...
£40000 - £60000 per annum + EXCELLENT SALARY: Austen Lloyd: Senior Private Cli...
£25,000 to £35,000: IT Connections Ltd: Signal Processing Engineer / Acoustics...