Genetic test may predict fertility
Monday 18 October 2010
A simple genetic test could in future help women predict their reproductive lifespan.
Scientists have identified four genes that affect menopausal age. In combination they have a larger impact, leading some women to reach "the change" unusually early.
Study leader Anna Murray, from the University of Exeter Peninsula Medical School, said: "It is estimated that a woman's ability to conceive decreases on average 10 years before she starts the menopause. Therefore, those who are destined to have an early menopause and delay childbearing until their 30s are more likely to have problems conceiving. These findings are the first stage in developing an easy and relatively inexpensive genetic test which could help the one in 20 UK women who may be affected by early menopause."
Women taking part in the research were participants in the Breakthrough Generations Study, an investigation into breast cancer.
A total of 2,000 women who had experienced early menopause were compared with a matched number who had not. DNA tests identified the four genes that each raise the risk of an early menopause. The findings were published in the journal Human Molecular Genetics.
Professor Anthony Swerdlow, from the Institute of Cancer Research, said: "We have made a valuable step towards helping women identify and predict whether they are at risk of early menopause. This may in turn allow them to make informed decisions about their future fertility."
- 1 Toddler throws a tantrum at the White House – in front of Barack Obama
- 2 Irish people are travelling home from all over the world so they can vote to legalise gay marriage
- 3 Picture of couple posing with beached dolphin 'that later died' causes outrage
- 4 16-year-old girl beaten and burned alive by lynch mob in Rio Bravo, Guatemala
- 5 Witch doctor arrested after forcing newborn baby to walk in Indian village
Toddler throws a tantrum at the White House – in front of Barack Obama
Maryland mother found pushing her dead child on a swing in a playground
16-year-old girl beaten and burned alive by lynch mob in Rio Bravo, Guatemala
Picture of couple posing with beached dolphin 'that later died' causes outrage
Nicola Sturgeon did want David Cameron to win the general election, report concludes
As a white man, I'm surprised more women aren't tweeting the hashtag #KillAllWhiteMen
Scotland may have to leave the EU even if it votes to stay in, David Cameron confirms
Report finds that Britain's wages are the most unequal in Europe
Almost a third of school pupils believe 'Muslims are taking over our country', study claims
The day that Britain resigned as a global power
Gay marriage 'Bert and Ernie' cake bakery found guilty of discrimination in Northern Ireland
£40-50K: Guru Careers: We are seeking an experienced Software / C# Developer w...
£35 - 40k + Benefits: Guru Careers: We are seeking a Software Developer (JavaS...
£18000 - £23000 per annum + Commission: SThree: As a Trainee Recruitment Consu...