High doses of antidepressants 'double chances of suicidal behaviour in teens'
High starting doses of antidepressants such as Prozac have been linked to increased suicidal behaviour in children and young adults, say scientists.
A meta-analysis of various antidepressant drug trials by the US Food and Drug Administration (FDA) found that young people who received antidepressants were twice as likely to have suicidal thoughts or self-harm as those given a placebo.
The study collected data from 162,625 people between the ages of 10 to 64 who had been proscribed antidepressants at modal (the most prescribed on average) or above modal doses, and compared the two groups.
Those aged 24 or younger that started treatment at higher doses was twice as likely to self-harm, with older patients remaining unaffected. The authors of the study suggest that this corresponds to approximately one additional case of self-harm for every 150 patients.
The doctors who conducted the study from the Harvard School of Public Health recommended that doctors should avoid high doses for younger individuals as the benefits are at best “modest”.
A similar study conducted by the British Medical Journal in 2009 also found that young adults taking antidepressants such as SSRIs had double the risk of suicidal thoughts or behaviour when compared to those taking placebos.
SSRIs are a type of antidepressant marketed under many different commercial names including Prozac, Zoloft, Paxil and Seroxat.
- 1 President of Argentina adopts Jewish godson to 'stop him turning into a werewolf'
- 2 The 'Black Museum': After 150 years, public set to see exhibits from police’s grisly crime museum
- 4 Sir Winston Churchill’s family begged him not to convert to Islam, letter reveals
- 5 UK weather: 'Coldest night of the year' tonight as freezing temperatures plummet to -10C
President of Argentina adopts Jewish godson to 'stop him turning into a werewolf'
Exclusive: Abusers using spyware apps to monitor partners reaches 'epidemic proportions'
Stoke-on-Trent becomes first British city to be classified as 'disaster resilient' by the United Nations
Sir Winston Churchill’s family begged him not to convert to Islam, letter reveals
AirAsia flight QZ8501 missing: Search for plane carrying 162 passengers from Indonesia to Singapore suspended overnight
Millions of Britons struggling to feed themselves and facing malnourishment
British actor Idris Elba cannot star as James Bond because he is black, says shock jock Rush Limbaugh
Ukip member gets into Christmas spirit with Union Flag plea to Santa 'for our country back'
Germany anti-Islam protests: 17,000 march on Dresden against 'Islamification of the West'
Nigel Farage: Ukip leader named 'Briton of the year' by The Times
Immigrants make UK racist, says Ukip councillor Trevor Shonk
£32000 - £40000 per annum: Recruitment Genius: A Business Manager is required ...
£45000 - £55000 per annum: Recruitment Genius: This is an exciting opportunity...
£20000 per annum: Recruitment Genius: Panel Wireman required for small electro...
£25000 - £27000 per annum: Recruitment Genius: An SME based in East Cheshire, ...