High doses of antidepressants 'double chances of suicidal behaviour in teens'
High starting doses of antidepressants such as Prozac have been linked to increased suicidal behaviour in children and young adults, say scientists.
A meta-analysis of various antidepressant drug trials by the US Food and Drug Administration (FDA) found that young people who received antidepressants were twice as likely to have suicidal thoughts or self-harm as those given a placebo.
The study collected data from 162,625 people between the ages of 10 to 64 who had been proscribed antidepressants at modal (the most prescribed on average) or above modal doses, and compared the two groups.
Those aged 24 or younger that started treatment at higher doses was twice as likely to self-harm, with older patients remaining unaffected. The authors of the study suggest that this corresponds to approximately one additional case of self-harm for every 150 patients.
The doctors who conducted the study from the Harvard School of Public Health recommended that doctors should avoid high doses for younger individuals as the benefits are at best “modest”.
A similar study conducted by the British Medical Journal in 2009 also found that young adults taking antidepressants such as SSRIs had double the risk of suicidal thoughts or behaviour when compared to those taking placebos.
SSRIs are a type of antidepressant marketed under many different commercial names including Prozac, Zoloft, Paxil and Seroxat.
- 2 How the language you speak changes your view of the world
- 3 Russell Brand backs Ed Miliband: 'You gotta vote Labour'
- 4 General Election 2015: 14-year-old boy asks Nick Clegg – 'can you kill Katie Hopkins?'
Lucy Hawking: Stephen Hawking's daughter writes impassioned open letter to Katie Hopkins about rights of disabled people
Oxygen-starved 'dead zones' with no marine life up to 100-miles long discovered in the Atlantic Ocean
How the language you speak changes your view of the world
General election live: Russell Brand endorses Labour (except in Scotland and Brighton)
Russell Brand backs Ed Miliband: 'You gotta vote Labour'
Over 50,000 families shipped out of London boroughs in the past three years due to welfare cuts and soaring rents
EU asylum policy is 'a direct threat to our civilisation', says Nigel Farage
The Rothschild Libel: Why has it taken 200 years for an anti-Semitic slur that emerged from the Battle of Waterloo to be dismissed?
General Election 2015: SNP and its activists 'openly racist' towards the English, Farage says
General Election 2015: UK will be 'run for the wealthy and powerful' if Tories retain power, Labour warns
Schools forced to act as 'miniature welfare states' with teachers buying underwear and even haircuts for poor pupils
£25000 per annum: Ashdown Group: A successful professional services firm is lo...
£25000 per annum + pension, 25 days holiday: Ashdown Group: A highly reputable...
£25000 per annum: Ashdown Group: A highly reputable business is looking to rec...
£22000 - £28000 per annum + study support, gym: Ashdown Group: A large busines...