In a clip posted on YouTube, CNN's Randi Kaye is seen doing "extensive research" on Colorado's revised cannabis laws, reporting that she suddenly "found things to be really funny".
Scroll down for the video - interview starts at 4:30
The latest instalment of the news network's Gone To Pot series focuses on cannabis tours, with Kaye joining a group of people in the back of a stretch Hummer as they visit a number of newly-opened pot dispensaries.
The reporter is seen getting "contact high" in in the back of the smoky limo, becoming gradually more giggly as the segment continues.
The report ends with the group, now several joints deep, "demanding tacos" before Kaye talks to CNN anchor Anderson Cooper about her experience.
"It was top notch, we did very extensive research I have to tell you," a smiley Kaye says.
"My brain was a little fuzzy by the time I got out of there, I wasn't thinking right and I couldn't remember even some of the questions I wanted to ask in the interview, which has never happened to me.
"And I found things to be really funny, much funnier than I normally do," she adds.
Marijuana sales have boomed since the drug was legalised in the state, with licensed sellers thought to have raked in more than $1 million on the first day alone.
Video: Colorado marijuana sales rise