India took a 2-0 series lead against Australia as the tourists slumped to an innings and 135-run defeat in the second Test in Hyderabad with close to two days to spare.
Australia had begun the fourth day hoping to make a good fist of holding out for a draw but lost eight wickets for just 57 runs.
The tourists had begun the day on 74 for two, trailing by 192 runs, but they were bowled out for 131.
Australia had made 237 for nine declared in their first innings but when India replied with 503 they faced an uphill task.
Ravichandran Ashwin finished the second innings with five for 63 and Ravindra Jadeja three for 33 as India built on their eight-wicket win in Chennai to lead the series 2-0 with two Tests remaining.
Only Ed Cowan, with a patient 44 from 150 balls, offered any real resistance to the home side's slow bowling attack.
Australia lost Shane Watson, caught by captain MS Dhoni off Ishant Sharma for nine, and skipper Michael Clarke when he was bowled by Jadeja for 16.
But when Cowan was the fifth wicket to fall and the third of the morning, Virender Sehwag taking the catch off Jadeja, Australia were in serious trouble at 111 for five.
Moises Henriques was run out without further addition to the scoreboard as Australia added to their troubles.
Glenn Maxwell (8), Peter Siddle (4), Matthew Wade (10) and James Pattinson (0) ensured Australia struggled to 131, leaving Xavier Doherty unbeaten on one.
But their combined efforts could not prevent a defeat of an innings and 135 runs, leaving Clarke to regret his decision to declare on day one.
The tourists had looked to make inroads into India's innings but found the home side in determined mood as they went on to eventually pass 500 runs, Cheteshwar Pujara scoring 204 and Murali Vijay 167.
That meant Australia had become the first team to declare on first innings and then lose by an innings in Test cricket.
With two matches remaining in Mohali and Delhi all Clarke can hope for is to salvage a draw from the series, but after two convincing defeats those hopes look slim.