Martin Jol will rotate his squad for Fulham's Capital One Cup second round tie against Sheffield Wednesday tonight.
The Cottagers have made an encouraging start to the season, thrashing Norwich 5-0 on the opening day of the campaign and almost snatching a point at Manchester United on Saturday.
Jol is confident he has the depth in his squad to field an alternative line-up at Hillsborough.
"There will be a few changes. We have 18 or 19 players," Jol said.
"They are good enough to come in for some others. I can give three or four players a rest."
Centre Aaron Hughes predicts Fulham are going to enjoy a successful season.
"We did really well against Norwich and there's a lot we can take from the Man Utd game too," Hughes told the club's official website, http://www.fulhamfc.com.
"It's been a good start, but there's a long way to go yet.
"We're solid at the back, have players with a lot of creativity in midfield and up front we can score goals - it's a nice balance.
"With that in mind, looking ahead, we could have a good season."