i Philip Pullman, author

Say a little prayer for me?

Experimental drug provides fresh hope for Alzheimer's patients

An experimental drug has been shown to halt memory loss in mice with a rodent version of Alzheimer's disease.

Bexarotene, sold under the name Targretin, had caused ripples of excitement across the medical profession, following high profile research that suggested it could be used to treat the symptoms of Alzheimer’s.

Pioneering method of treating Alzheimer’s discredited by scientists

Bexarotene, sold under the name Targretin, had caused ripples of excitement across the medical profession

(l-r) Phoebe Aldridge (LUCY MORRIS), Roy Tucker (IAN PEPPERELL), Hayley Tucker (Lorraine Coady) in The Archers

The Archers 'does not compete with EastEnders' for sensational storylines

The Archers' outgoing editor Vanessa Whitburn has denied that the drama has been competing with soaps such as EastEnders for sensational storylines.

Britain will use G8 to aid dementia research

David Cameron plans to use Britain’s presidency of the G8 leading industrialised nations to spearhead a new international drive to boost dementia research.

The 10 Best sponsored cycle rides

Whether it's pedalling through Dorset or from John O'Groats to Land's End, we look at the best ways to raise money and keep fit

Arnold Peters in Golden Hill

The Archers actor Arnold Peters dies aged 87

Veteran actor Arnold Peters, who was known for his role as Jack Woolley in The Archers for more than 30 years, has died at the age of 87.

It is a year since the Prime Minister launched the Dementia Challenge, which seeks to make the UK a leader in research into the degenerative brain disesases of which Alzheimer’s is the best known

Alzheimer’s fair opens in UK as dementia becomes big business

With 65 per cent of us likely to know a sufferer, products are being devised to help patients

Prime Minister David Cameron helping Baroness Thatcher outside Downing Street

Stroke factfile: the killer which affects 150,000 a year

About 150,000 people suffer a stroke every year. A third make a good recovery within a month. Most however, have long term difficulties with speech or movement and the worst affected die.

A tearful Carla Bruni,left, has dismissed as “unthinkable” the accusation that her husband, Nicolas Sarkozy, took advantage of the mental frailty of an elderly billionaire to finance his rise to power

Tearful Carla Bruni rejects claim Nicolas Sarkozy badgered L’Oréal heiress Liliane Bettencourt

A tearful Carla Bruni has dismissed as “unthinkable” the accusation that her husband, Nicolas Sarkozy, took advantage of the mental frailty of an elderly billionaires to finance his rise to power.

Sleep problems are common among people with full-blown Alzheimer's

Sleep problems? Scientists warn of possible early sign of Alzheimer's

Sleep loss can be an early warning sign of Alzheimer's, new research suggests.

My Secret Life: Samuel L Jackson, 64, actor

'No one tells me I'm no good at things'

'Less than half' of dementia sufferers have 'good quality of life' in care homes

Charity warns 80 per cent of people in care have condition

Chisnall bursts through for Warrington against Bradford Northern

Dave Chisnall: Powerful, pacey Warrington prop

Dave Chisnall was a member of a notable rugby league family and one of the very few players to miss a Wembley final through suspension.

HRT 'protects' against rapid ageing that may be linked to Alzheimer's disease, study finds

Hormone replacement therapy (HRT) can block signs of accelerated ageing that may be linked to Alzheimer's disease, a study has found.

'Not up to standard': 25% of care agencies providing services to people in their homes are failing

A quarter of agencies that provide care to people in their own homes do not meet all five national standards of quality and safety, regulators said.

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Independent Travel
Burgundy, the River Rhone & Provence – Five-star MS Swiss Corona 7 nights from £999pp
Lake Como St Moritz & the Bernina Express 7 nights from £809pp
Vietnam
Lake Maggiore, Orta & the Matterhorn 7 nights from £939pp
South Africa
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Prices correct as of 19 December 2014
A Christmas without hope: Fears grow in Gaza that the conflict with Israel will soon reignite

Christmas without hope

Gaza fears grow that conflict with Israel will soon reignite
After 150 years, you can finally visit the grisliest museum in the country

The 'Black Museum'

After 150 years, you can finally visit Britain's grisliest museum
No ho-ho-hos with Nick Frost's badass Santa

No ho-ho-hos with Nick Frost's badass Santa

Doctor Who Christmas Special TV review
Chilly Christmas: Swimmers take festive dip for charity

Chilly Christmas

Swimmers dive into freezing British waters for charity
Veterans' hostel 'overwhelmed by kindness' for festive dinner

Homeless Veterans appeal

In 2010, Sgt Gary Jamieson stepped on an IED in Afghanistan and lost his legs and an arm. He reveals what, and who, helped him to make a remarkable recovery
Isis in Iraq: Yazidi girls killing themselves to escape rape and imprisonment by militants

'Jilan killed herself in the bathroom. She cut her wrists and hanged herself'

Yazidi girls killing themselves to escape rape and imprisonment
Ed Balls interview: 'If I think about the deficit when I'm playing the piano, it all goes wrong'

Ed Balls interview

'If I think about the deficit when I'm playing the piano, it all goes wrong'
He's behind you, dude!

US stars in UK panto

From David Hasselhoff to Jerry Hall
Grace Dent's Christmas Quiz: What are you – a festive curmudgeon or top of the tree?

Grace Dent's Christmas Quiz

What are you – a festive curmudgeon or top of the tree?
Nasa planning to build cloud cities in airships above Venus

Nasa planning to build cloud cities in airships above Venus

Planet’s surface is inhospitable to humans but 30 miles above it is almost perfect
Surrounded by high-rise flats is a little house filled with Lebanon’s history - clocks, rifles, frogmen’s uniforms and colonial helmets

Clocks, rifles, swords, frogmen’s uniforms

Surrounded by high-rise flats is a little house filled with Lebanon’s history
Return to Gaza: Four months on, the wounds left by Israel's bombardment have not yet healed

Four months after the bombardment, Gaza’s wounds are yet to heal

Kim Sengupta is reunited with a man whose plight mirrors the suffering of the Palestinian people
Gastric surgery: Is it really the answer to the UK's obesity epidemic?

Is gastric surgery really the answer to the UK's obesity epidemic?

Critics argue that it’s crazy to operate on healthy people just to stop them eating
Homeless Veterans appeal: Christmas charity auction Part 2 - now LIVE

Homeless Veterans appeal: Christmas charity auction

Bid on original art, or trips of a lifetime to Africa or the 'Corrie' set, and help Homeless Veterans
Pantomime rings the changes to welcome autistic theatre-goers

Autism-friendly theatre

Pantomime leads the pack in quest to welcome all