i Philip Pullman, author

Say a little prayer for me?

Experimental drug provides fresh hope for Alzheimer's patients

An experimental drug has been shown to halt memory loss in mice with a rodent version of Alzheimer's disease.

Bexarotene, sold under the name Targretin, had caused ripples of excitement across the medical profession, following high profile research that suggested it could be used to treat the symptoms of Alzheimer’s.

Pioneering method of treating Alzheimer’s discredited by scientists

Bexarotene, sold under the name Targretin, had caused ripples of excitement across the medical profession

(l-r) Phoebe Aldridge (LUCY MORRIS), Roy Tucker (IAN PEPPERELL), Hayley Tucker (Lorraine Coady) in The Archers

The Archers 'does not compete with EastEnders' for sensational storylines

The Archers' outgoing editor Vanessa Whitburn has denied that the drama has been competing with soaps such as EastEnders for sensational storylines.

Britain will use G8 to aid dementia research

David Cameron plans to use Britain’s presidency of the G8 leading industrialised nations to spearhead a new international drive to boost dementia research.

The 10 Best sponsored cycle rides

Whether it's pedalling through Dorset or from John O'Groats to Land's End, we look at the best ways to raise money and keep fit

Arnold Peters in Golden Hill

The Archers actor Arnold Peters dies aged 87

Veteran actor Arnold Peters, who was known for his role as Jack Woolley in The Archers for more than 30 years, has died at the age of 87.

It is a year since the Prime Minister launched the Dementia Challenge, which seeks to make the UK a leader in research into the degenerative brain disesases of which Alzheimer’s is the best known

Alzheimer’s fair opens in UK as dementia becomes big business

With 65 per cent of us likely to know a sufferer, products are being devised to help patients

Prime Minister David Cameron helping Baroness Thatcher outside Downing Street

Stroke factfile: the killer which affects 150,000 a year

About 150,000 people suffer a stroke every year. A third make a good recovery within a month. Most however, have long term difficulties with speech or movement and the worst affected die.

A tearful Carla Bruni,left, has dismissed as “unthinkable” the accusation that her husband, Nicolas Sarkozy, took advantage of the mental frailty of an elderly billionaire to finance his rise to power

Tearful Carla Bruni rejects claim Nicolas Sarkozy badgered L’Oréal heiress Liliane Bettencourt

A tearful Carla Bruni has dismissed as “unthinkable” the accusation that her husband, Nicolas Sarkozy, took advantage of the mental frailty of an elderly billionaires to finance his rise to power.

Sleep problems are common among people with full-blown Alzheimer's

Sleep problems? Scientists warn of possible early sign of Alzheimer's

Sleep loss can be an early warning sign of Alzheimer's, new research suggests.

My Secret Life: Samuel L Jackson, 64, actor

'No one tells me I'm no good at things'

'Less than half' of dementia sufferers have 'good quality of life' in care homes

Charity warns 80 per cent of people in care have condition

Chisnall bursts through for Warrington against Bradford Northern

Dave Chisnall: Powerful, pacey Warrington prop

Dave Chisnall was a member of a notable rugby league family and one of the very few players to miss a Wembley final through suspension.

HRT 'protects' against rapid ageing that may be linked to Alzheimer's disease, study finds

Hormone replacement therapy (HRT) can block signs of accelerated ageing that may be linked to Alzheimer's disease, a study has found.

'Not up to standard': 25% of care agencies providing services to people in their homes are failing

A quarter of agencies that provide care to people in their own homes do not meet all five national standards of quality and safety, regulators said.

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Pompeii, Capri & the Bay of Naples
Seven Cities of Italy
Burgundy, the River Rhone & Provence
Prague, Budapest and Vienna
Lake Garda
Minoan Crete and Santorini
Prices correct as of 15 May 2015
War with Isis: Is Turkey's buffer zone in Syria a matter of self-defence – or just anti-Kurd?

Turkey's buffer zone in Syria: self-defence – or just anti-Kurd?

Ankara accused of exacerbating racial division by allowing Turkmen minority to cross the border
Doris Lessing: Acclaimed novelist was kept under MI5 observation for 18 years, newly released papers show

'A subversive brothel keeper and Communist'

Acclaimed novelist Doris Lessing was kept under MI5 observation for 18 years, newly released papers show
Big Blue Live: BBC's Springwatch offshoot swaps back gardens for California's Monterey Bay

BBC heads to the Californian coast

The Big Blue Live crew is preparing for the first of three episodes on Sunday night, filming from boats, planes and an aquarium studio
Austin Bidwell: The Victorian fraudster who shook the Bank of England with the most daring forgery the world had known

Victorian fraudster who shook the Bank of England

Conman Austin Bidwell. was a heartless cad who carried out the most daring forgery the world had known
Car hacking scandal: Security designed to stop thieves hot-wiring almost every modern motor has been cracked

Car hacking scandal

Security designed to stop thieves hot-wiring almost every modern motor has been cracked
10 best placemats

Take your seat: 10 best placemats

Protect your table and dine in style with a bold new accessory
Ashes 2015: Alastair Cook not the only one to be caught in The Oval mindwarp

Cook not the only one to be caught in The Oval mindwarp

Aussie skipper Michael Clarke was lured into believing that what we witnessed at Edgbaston and Trent Bridge would continue in London, says Kevin Garside
Can Rafael Benitez get the best out of Gareth Bale at Real Madrid?

Can Benitez get the best out of Bale?

Back at the club he watched as a boy, the pressure is on Benitez to find a winning blend from Real's multiple talents. As La Liga begins, Pete Jenson asks if it will be enough to stop Barcelona
Athletics World Championships 2015: Beijing witnesses new stage in the Jessica Ennis-Hill and Katarina Johnson-Thompson heptathlon rivalry

Beijing witnesses new stage in the Jess and Kat rivalry

The last time the two British heptathletes competed, Ennis-Hill was on the way to Olympic gold and Johnson-Thompson was just a promising teenager. But a lot has happened in the following three years
Jeremy Corbyn: Joining a shrewd operator desperate for power as he visits the North East

Jeremy Corbyn interview: A shrewd operator desperate for power

His radical anti-austerity agenda has caught the imagination of the left and politically disaffected and set a staid Labour leadership election alight
Isis executes Palmyra antiquities chief: Defender of ancient city's past was killed for protecting its future

Isis executes Palmyra antiquities chief

Robert Fisk on the defender of the ancient city's past who was killed for protecting its future
Berlusconi's world of sleaze: The astonishing lifestyle once enjoyed by Italy's former PM

Berlusconi's world of sleaze

The astonishing lifestyle once enjoyed by Italy's former PM
Disney plans galactic domination with endless Star Wars spin-offs

Disney plans galactic domination with endless Star Wars spin-offs

Films and theme parks are just the beginning. Disney believes its control of the now decades-old franchise can bring in merchandise and marketing millions for years to come
Could the golden age of the gaming arcade ever be revived in the era of the Xbox?

Could gaming arcades be revived?

The days when coin-ops were the only way to play the latest video games are gone. But a small band of enthusiasts are keeping the button-pushing dream alive
Edinburgh Fringe 2015: The 'tampon tax' has inspired a new wave of female comedians to reclaim period jokes

Heard the one about menstruation?

Yes, if you have been at the Fringe, where period pieces are taking centre stage