i Philip Pullman, author

Say a little prayer for me?

Single pill could be used to treat Alzheimer's, Parkinson's and multiple sclerosis

A single pill has the potential to treat multiple brain conditions including Alzheimer's, Parkinson's and multiple sclerosis, it has been revealed.

Binge-drink OAPs risk brain damage, warn scientists

Pensioners were warned today not to binge-drink after new research revealed they could be damaging their brains.

New drug immunoglobulin could give three-year reprieve from Alzheimer's

Substance made from antibodies in human blood could be on the shelves in 10 years

The Long Earth, By Terry Pratchett and Stephen Baxter

One small Stepper for mankind

John Simpson with partner Dee Kruger and son Rafe

BBC broadcaster John Simpson says he plans to commit suicide rather than allow young son to see him as a 'gibbering wreck' in old age

The veteran correspondent said "I don’t want my 6 year-old son to have his only memory of me as a gibbering wreck"

Warning on financial scams targeting the elderly

Older people are being warned not to fall prey to bogus retail and investment schemes, after 78 rogue companies raking in more than £28 million from people were shut down in the last three years alone.

Heather Roberts, 57, pictured with her daughter Frances, 27: 'It was frustrating that it was such a hard fight to be diagnosed'

Most GPs can't recognise signs of Alzheimer's

Early treatment alleviates symptoms but only 37 per cent of doctors are trained to identify it

Two-year-old Tilly is being trained to carry medicine for her owner at Dogs for the Disabled in Banbury

Guide dogs for the mind to fight dementia

Animals will help Alzheimer's patients remember their medicine and steer them through the day

Best Friends: Rob Brydon and Steve Coogan exchange confidences and laughter in The Trip, and we love to listen in

The Listening Project: Yes, it's good to talk. But the real joy is in being allowed to listen

As the BBC airs intimate conversations, project deviser Tony Phillips finds he is deeply moved

Alzheimer’s treatment in late stages of disease does slow progression

More than 100,000 people in the UK suffering the “savage” effects of advanced Alzheimer’s disease could benefit from drug treatment to slow its progression.

Chemical link revealed in Alzheimer's study

Alzheimer's symptoms such as memory loss could be prevented by targeting a chemical that dismantles brain connections, research suggests.

Meryl Streep looks and sounds like Margaret Thatcher, but also suggests her vulnerability

The Iron Lady, Phyllida Lloyd, 105 mins (12A)

Meryl Streep is superb, but the story is of one woman fulfilling her destiny rather than the pell-mell of politics

Leading article: An issue of dignity that can no longer be avoided

Even with all the benefits of medicine, the terminally ill may face extreme pain and indignity

DVD: Rise of the Planet of the Apes (12)

"Are you sure you're not rushing?" James Franco's Will is reasonably asked.

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Fifa corruption: The 161-page dossier that exposes the organisation's dark heart

The 161-page dossier that exposes Fifa's dark heart

How did a group of corrupt officials turn football’s governing body into what was, in essence, a criminal enterprise? Chris Green and David Connett reveal all
Mediterranean migrant crisis: 'If Europe thinks bombing boats will stop smuggling, it will not. We will defend ourselves,' says Tripoli PM

Exclusive interview with Tripoli PM Khalifa al-Ghweil

'If Europe thinks bombing boats will stop smuggling, it will not. We will defend ourselves'
Raymond Chandler's Los Angeles: How the author foretold the Californian water crisis

Raymond Chandler's Los Angeles

How the author foretold the Californian water crisis
Chinese artist who posted funny image of President Xi Jinping facing five years in prison as authorities crackdown on dissent in the arts

Art attack

Chinese artist who posted funny image of President Xi Jinping facing five years in prison
Marc Jacobs is putting Cher in the limelight as the face of his latest campaign

Cher is the new face of Marc Jacobs

Alexander Fury explains why designers are turning to august stars to front their lines
Parents of six-year-old who beat leukaemia plan to climb Ben Nevis for cancer charity

'I'm climbing Ben Nevis for my daughter'

Karen Attwood's young daughter Yasmin beat cancer. Now her family is about to take on a new challenge - scaling Ben Nevis to help other children
10 best wedding gift ideas

It's that time of year again... 10 best wedding gift ideas

Forget that fancy toaster, we've gone off-list to find memorable gifts that will last a lifetime
Paul Scholes column: With the Premier League over for another year, here are my end of season awards

Paul Scholes column

With the Premier League over for another year, here are my end of season awards
Heysel disaster 30th anniversary: Liverpool have seen too much tragedy to forget fateful day in Belgium

Liverpool have seen too much tragedy to forget Heysel

Thirty years ago, 39 fans waiting to watch a European Cup final died as a result of a fatal cocktail of circumstances. Ian Herbert looks at how a club dealt with this tragedy
Amir Khan vs Chris Algieri: Khan’s audition for Floyd Mayweather may turn into a no-win situation, says Frank Warren

Khan’s audition for Mayweather may turn into a no-win situation

The Bolton fighter could be damned if he dazzles and damned if he doesn’t against Algieri, the man last seen being decked six times by Pacquiao, says Frank Warren
Blundering Tony Blair quits as Middle East peace envoy – only Israel will miss him

Blundering Blair quits as Middle East peace envoy – only Israel will miss him

For Arabs – and for Britons who lost their loved ones in his shambolic war in Iraq – his appointment was an insult, says Robert Fisk
Fifa corruption arrests: All hail the Feds for riding to football's rescue

Fifa corruption arrests

All hail the Feds for riding to football's rescue, says Ian Herbert
Isis in Syria: The Kurdish enclave still resisting the tyranny of President Assad and militant fighters

The Kurdish enclave still resisting the tyranny of Assad and Isis

In Syrian Kurdish cantons along the Turkish border, the progressive aims of the 2011 uprising are being enacted despite the war. Patrick Cockburn returns to Amuda
How I survived Cambodia's Killing Fields: Acclaimed surgeon SreyRam Kuy celebrates her mother's determination to escape the US

How I survived Cambodia's Killing Fields

Acclaimed surgeon SreyRam Kuy celebrates her mother's determination to escape to the US
Stephen Mangan interview: From posh buffoon to pregnant dad, the actor has quite a range

How Stephen Mangan got his range

Posh buffoon, hapless writer, pregnant dad - Mangan is certainly a versatile actor