i Philip Pullman, author

Say a little prayer for me?

Single pill could be used to treat Alzheimer's, Parkinson's and multiple sclerosis

A single pill has the potential to treat multiple brain conditions including Alzheimer's, Parkinson's and multiple sclerosis, it has been revealed.

Binge-drink OAPs risk brain damage, warn scientists

Pensioners were warned today not to binge-drink after new research revealed they could be damaging their brains.

New drug immunoglobulin could give three-year reprieve from Alzheimer's

Substance made from antibodies in human blood could be on the shelves in 10 years

The Long Earth, By Terry Pratchett and Stephen Baxter

One small Stepper for mankind

John Simpson with partner Dee Kruger and son Rafe

BBC broadcaster John Simpson says he plans to commit suicide rather than allow young son to see him as a 'gibbering wreck' in old age

The veteran correspondent said "I don’t want my 6 year-old son to have his only memory of me as a gibbering wreck"

Warning on financial scams targeting the elderly

Older people are being warned not to fall prey to bogus retail and investment schemes, after 78 rogue companies raking in more than £28 million from people were shut down in the last three years alone.

Heather Roberts, 57, pictured with her daughter Frances, 27: 'It was frustrating that it was such a hard fight to be diagnosed'

Most GPs can't recognise signs of Alzheimer's

Early treatment alleviates symptoms but only 37 per cent of doctors are trained to identify it

Two-year-old Tilly is being trained to carry medicine for her owner at Dogs for the Disabled in Banbury

Guide dogs for the mind to fight dementia

Animals will help Alzheimer's patients remember their medicine and steer them through the day

Best Friends: Rob Brydon and Steve Coogan exchange confidences and laughter in The Trip, and we love to listen in

The Listening Project: Yes, it's good to talk. But the real joy is in being allowed to listen

As the BBC airs intimate conversations, project deviser Tony Phillips finds he is deeply moved

Alzheimer’s treatment in late stages of disease does slow progression

More than 100,000 people in the UK suffering the “savage” effects of advanced Alzheimer’s disease could benefit from drug treatment to slow its progression.

Chemical link revealed in Alzheimer's study

Alzheimer's symptoms such as memory loss could be prevented by targeting a chemical that dismantles brain connections, research suggests.

Meryl Streep looks and sounds like Margaret Thatcher, but also suggests her vulnerability

The Iron Lady, Phyllida Lloyd, 105 mins (12A)

Meryl Streep is superb, but the story is of one woman fulfilling her destiny rather than the pell-mell of politics

Leading article: An issue of dignity that can no longer be avoided

Even with all the benefits of medicine, the terminally ill may face extreme pain and indignity

DVD: Rise of the Planet of the Apes (12)

"Are you sure you're not rushing?" James Franco's Will is reasonably asked.

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Nick Frost will star in the Doctor Who 2014 Christmas special
tvNick Frost, Natalie Gumede and Michael Troughton step up
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Matthew Beard, Ben Schnetzer, Douglas Booth and Jack Farthing in ‘The Riot Club’
filmReview: Sheer nastiness of Riot Club takes you aback
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Mystery of the Ground Zero wedding photo

A shot in the dark

Mystery of the wedding photo from Ground Zero
His life, the universe and everything

His life, the universe and everything

New biography sheds light on comic genius of Douglas Adams
Save us from small screen superheroes

Save us from small screen superheroes

Shows like Agents of S.H.I.E.L.D are little more than marketing tools
Reach for the skies

Reach for the skies

From pools to football pitches, rooftop living is looking up
These are the 12 best hotel spas in the UK

12 best hotel spas in the UK

Some hotels go all out on facilities; others stand out for the sheer quality of treatments
These Iranian-controlled Shia militias used to specialise in killing American soldiers. Now they are fighting Isis, backed up by US airstrikes

Widespread fear of Isis is producing strange bedfellows

Iranian-controlled Shia militias that used to kill American soldiers are now fighting Isis, helped by US airstrikes
Topshop goes part Athena poster, part last spring Prada

Topshop goes part Athena poster, part last spring Prada

Shoppers don't come to Topshop for the unique
How to make a Lego masterpiece

How to make a Lego masterpiece

Toy breaks out of the nursery and heads for the gallery
Meet the ‘Endies’ – city dwellers who are too poor to have fun

Meet the ‘Endies’ – city dwellers who are too poor to have fun

Urbanites are cursed with an acronym pointing to Employed but No Disposable Income or Savings
Paisley’s decision to make peace with IRA enemies might remind the Arabs of Sadat

Ian Paisley’s decision to make peace with his IRA enemies

His Save Ulster from Sodomy campaign would surely have been supported by many a Sunni imam
'She was a singer, a superstar, an addict, but to me, her mother, she is simply Amy'

'She was a singer, a superstar, an addict, but to me, her mother, she is simply Amy'

Exclusive extract from Janis Winehouse's poignant new memoir
Is this the role to win Cumberbatch an Oscar?

Is this the role to win Cumberbatch an Oscar?

The Imitation Game, film review
England and Roy Hodgson take a joint step towards redemption in Basel

England and Hodgson take a joint step towards redemption

Welbeck double puts England on the road to Euro 2016
Relatives fight over Vivian Maier’s rare photos

Relatives fight over Vivian Maier’s rare photos

Pictures removed from public view as courts decide ownership
‘Fashion has to be fun. It’s a big business, not a cure for cancer’

‘Fashion has to be fun. It’s a big business, not a cure for cancer’

Donatella Versace at New York Fashion Week