i Philip Pullman, author

Say a little prayer for me?

Memory switch-on could help fight brain disease

Memories have been blocked and recovered in experiments that hold out the prospect of "artificial limbs for the mind" to combat Alzheimer's and other brain diseases. The experiments were done on rats and demonstrated that when an electronic switch implanted in the brain is flipped, the ability to retrieve memories returned.

Tim Lott: The top of a slippery moral slope

Anyone coming from a position of neutrality who watched Terry Pratchett's documentary on Monday, charting the assisted suicide of the motor neurone disease victim Peter Smedley would probably end up more in favour of assisted suicide than not.

Surprise discovery allows scientists to block Alzheimer's

Scientists developing treatments for the devastating brain disorder Creutzfeldt-Jakob Disease (CJD) have unexpectedly blocked the onset of Alzheimer's disease, the most common cause of dementia.

Southern Cross action plan demanded

The Government was tonight coming under increasing pressure to help end uncertainty over the future of thousands of elderly residents and staff at Britain's largest care homes group.

Exile, BBC1, Sunday, Monday, Tuesday<br/>The Shadow Line, BBC2, Thursday<br/>Psychoville, BBC2, Thursday

Alzheimer's-stricken family saves an over-busy thriller, while true terror lurks with a Silent Singer

Blood test could diagnose Alzheimer's disease

Scientists have developed a blood test which they believe could diagnose Alzheimer's disease in its early stages.

Pfizer sales fall after key patents expire

Falling sales of Pfizer's key cholesterol drug, Lipitor, in the face of generic competition hit sales at the American pharmaceuticals giants in the first quarter.

The Weekend's TV: Exile, Sun, BBC1<br/>Vera, Sun, ITV1

Secrets worth investigating

Pratchett presents film on Dignitas

The author Sir Terry Pratchett is to present a documentary about the last moments of a terminally ill man who travelled to the Dignitas assisted suicide clinic to end his life.

Mary Dejevsky: Genetic testing has little value if there's no chance of a cure

If you submit to screening at, say, the age of 40, and learn that you have a predisposition to Alzheimer's, what are you supposed to do about it?

A test for Alzheimer's disease &ndash; but will anyone want to take it?

Important new insights into Alzheimer's disease have emerged from the discovery of a handful of genes that are strongly implicated in raising a person's risk of developing the brain disorder in later life.

Sleep hormone 'may reduce dementia'

Doctors are leading a new study into a drug which could improve the quality of life for people with dementia.

David Rotheray, The Troubadour, London

His name may be top of the bill, but one habit dies hard for The Beautiful South's former guitarist and tunesmith. David Rotheray continues to write songs for male and female voices, with one of each on hand tonight.

The Winstones - Bring your daughter to the slaughter

A new British horror movie casts Ray and Jaime Winstone together in a film for the first time. On set in Wales, they reveal the secrets of the family profession to Charlotte Cripps

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War with Isis: Iraq declares victory in the battle for Tikrit - but militants make make ominous advances in neighbouring Syria's capital

War with Isis

Iraq declares victory in the battle for Tikrit - but militants make make ominous advances in neighbouring Syria
Scientists develop mechanical spring-loaded leg brace to improve walking

A spring in your step?

Scientists develop mechanical leg brace to help take a load off
Peter Ackroyd on Alfred Hitchcock: How London shaped the director's art and obsessions

Peter Ackroyd on Alfred Hitchcock

Ackroyd has devoted his literary career to chronicling the capital and its characters. He tells John Walsh why he chose the master of suspense as his latest subject
Ryan Reynolds interview: The actor is branching out with Nazi art-theft drama Woman in Gold

Ryan Reynolds branches out in Woman in Gold

For every box-office smash in Ryan Reynolds' Hollywood career, there's always been a misconceived let-down. It's time for a rethink and a reboot, the actor tells James Mottram
Why Robin Williams safeguarded himself against a morbid trend in advertising

Stars safeguard against morbid advertising

As film-makers and advertisers make increasing posthumous use of celebrities' images, some stars are finding new ways of ensuring that they rest in peace
The UK horticulture industry is facing a skills crisis - but Great Dixter aims to change all that

UK horticulture industry facing skills crisis

Great Dixter manor house in East Sussex is encouraging people to work in the industry by offering three scholarships a year to students, as well as generous placements
Hack Circus aims to turn the rule-abiding approach of TED talks on its head

Hack Circus: Technology, art and learning

Hack Circus aims to turn the rule-abiding approach of TED talks on its head. Rhodri Marsden meets mistress of ceremonies Leila Johnston
Sevenoaks is split over much-delayed decision on controversial grammar school annexe

Sevenoaks split over grammar school annexe

If Weald of Kent Grammar School is given the go-ahead for an annexe in leafy Sevenoaks, it will be the first selective state school to open in 50 years
10 best compact cameras

A look through the lens: 10 best compact cameras

If your smartphone won’t quite cut it, it’s time to invest in a new portable gadget
Paul Scholes column: Ross Barkley played well against Italy but he must build on that. His time to step up and seize that England No 10 shirt is now

Paul Scholes column

Ross Barkley played well against Italy but he must build on that. His time to step up and seize that England No 10 shirt is now
Why Michael Carrick is still proving an enigma for England

Why Carrick is still proving an enigma for England

Manchester United's talented midfielder has played international football for almost 14 years yet, frustratingly, has won only 32 caps, says Sam Wallace
Tracey Neville: The netball coach who is just as busy as her brothers, Gary and Phil

Tracey Neville is just as busy as her brothers, Gary and Phil

The former player on how she is finding time to coach both Manchester Thunder in the Superleague and England in this year's World Cup
General Election 2015: The masterminds behind the scenes

The masterminds behind the election

How do you get your party leader to embrace a message and then stick to it? By employing these people
Machine Gun America: The amusement park where teenagers go to shoot a huge range of automatic weapons

Machine Gun America

The amusement park where teenagers go to shoot a huge range of automatic weapons
The ethics of pet food: Why are we are so selective in how we show animals our love?

The ethics of pet food

Why are we are so selective in how we show animals our love?