i Philip Pullman, author

Say a little prayer for me?

Memory switch-on could help fight brain disease

Memories have been blocked and recovered in experiments that hold out the prospect of "artificial limbs for the mind" to combat Alzheimer's and other brain diseases. The experiments were done on rats and demonstrated that when an electronic switch implanted in the brain is flipped, the ability to retrieve memories returned.

Tim Lott: The top of a slippery moral slope

Anyone coming from a position of neutrality who watched Terry Pratchett's documentary on Monday, charting the assisted suicide of the motor neurone disease victim Peter Smedley would probably end up more in favour of assisted suicide than not.

Surprise discovery allows scientists to block Alzheimer's

Scientists developing treatments for the devastating brain disorder Creutzfeldt-Jakob Disease (CJD) have unexpectedly blocked the onset of Alzheimer's disease, the most common cause of dementia.

Southern Cross action plan demanded

The Government was tonight coming under increasing pressure to help end uncertainty over the future of thousands of elderly residents and staff at Britain's largest care homes group.

Exile, BBC1, Sunday, Monday, Tuesday<br/>The Shadow Line, BBC2, Thursday<br/>Psychoville, BBC2, Thursday

Alzheimer's-stricken family saves an over-busy thriller, while true terror lurks with a Silent Singer

Blood test could diagnose Alzheimer's disease

Scientists have developed a blood test which they believe could diagnose Alzheimer's disease in its early stages.

Pfizer sales fall after key patents expire

Falling sales of Pfizer's key cholesterol drug, Lipitor, in the face of generic competition hit sales at the American pharmaceuticals giants in the first quarter.

The Weekend's TV: Exile, Sun, BBC1<br/>Vera, Sun, ITV1

Secrets worth investigating

Pratchett presents film on Dignitas

The author Sir Terry Pratchett is to present a documentary about the last moments of a terminally ill man who travelled to the Dignitas assisted suicide clinic to end his life.

Mary Dejevsky: Genetic testing has little value if there's no chance of a cure

If you submit to screening at, say, the age of 40, and learn that you have a predisposition to Alzheimer's, what are you supposed to do about it?

A test for Alzheimer's disease &ndash; but will anyone want to take it?

Important new insights into Alzheimer's disease have emerged from the discovery of a handful of genes that are strongly implicated in raising a person's risk of developing the brain disorder in later life.

Sleep hormone 'may reduce dementia'

Doctors are leading a new study into a drug which could improve the quality of life for people with dementia.

David Rotheray, The Troubadour, London

His name may be top of the bill, but one habit dies hard for The Beautiful South's former guitarist and tunesmith. David Rotheray continues to write songs for male and female voices, with one of each on hand tonight.

The Winstones - Bring your daughter to the slaughter

A new British horror movie casts Ray and Jaime Winstone together in a film for the first time. On set in Wales, they reveal the secrets of the family profession to Charlotte Cripps

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Haunted looks: Matthew Macfadyen and Timothy Spall star in ‘The Enfield Haunting’
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Fishing for votes with Nigel Farage: The Ukip leader shows how he can work an audience as he casts his line to the disaffected of Grimsby

Fishing is on Nigel Farage's mind

Ukip leader casts a line to the disaffected
Who is bombing whom in the Middle East? It's amazing they don't all hit each other

Who is bombing whom in the Middle East?

Robert Fisk untangles the countries and factions
China's influence on fashion: At the top of the game both creatively and commercially

China's influence on fashion

At the top of the game both creatively and commercially
Lord O’Donnell: Former cabinet secretary on the election and life away from the levers of power

The man known as GOD has a reputation for getting the job done

Lord O'Donnell's three principles of rule
Rainbow shades: It's all bright on the night

Rainbow shades

It's all bright on the night
'It was first time I had ever tasted chocolate. I kept a piece, and when Amsterdam was liberated, I gave it to the first Allied soldier I saw'

Bread from heaven

Dutch survivors thank RAF for World War II drop that saved millions
Britain will be 'run for the wealthy and powerful' if Tories retain power - Labour

How 'the Axe' helped Labour

UK will be 'run for the wealthy and powerful' if Tories retain power
Rare and exclusive video shows the horrific price paid by activists for challenging the rule of jihadist extremists in Syria

The price to be paid for challenging the rule of extremists

A revolution now 'consuming its own children'
Welcome to the world of Megagames

Welcome to the world of Megagames

300 players take part in Watch the Skies! board game in London
'Nymphomaniac' actress reveals what it was really like to star in one of the most explicit films ever

Charlotte Gainsbourg on 'Nymphomaniac'

Starring in one of the most explicit films ever
Robert Fisk in Abu Dhabi: The Emirates' out-of-sight migrant workers helping to build the dream projects of its rulers

Robert Fisk in Abu Dhabi

The Emirates' out-of-sight migrant workers helping to build the dream projects of its rulers
Vince Cable interview: Charging fees for employment tribunals was 'a very bad move'

Vince Cable exclusive interview

Charging fees for employment tribunals was 'a very bad move'
Iwan Rheon interview: Game of Thrones star returns to his Welsh roots to record debut album

Iwan Rheon is returning to his Welsh roots

Rheon is best known for his role as the Bastard of Bolton. It's gruelling playing a sadistic torturer, he tells Craig McLean, but it hasn't stopped him recording an album of Welsh psychedelia
Russell Brand's interview with Ed Miliband has got everyone talking about The Trews

Everyone is talking about The Trews

Russell Brand's 'true news' videos attract millions of viewers. But today's 'Milibrand' interview introduced his resolutely amateurish style to a whole new crowd
Morne Hardenberg interview: Cameraman for BBC's upcoming show Shark on filming the ocean's most dangerous predator

It's time for my close-up

Meet the man who films great whites for a living