i Philip Pullman, author

Say a little prayer for me?

Memory switch-on could help fight brain disease

Memories have been blocked and recovered in experiments that hold out the prospect of "artificial limbs for the mind" to combat Alzheimer's and other brain diseases. The experiments were done on rats and demonstrated that when an electronic switch implanted in the brain is flipped, the ability to retrieve memories returned.

Tim Lott: The top of a slippery moral slope

Anyone coming from a position of neutrality who watched Terry Pratchett's documentary on Monday, charting the assisted suicide of the motor neurone disease victim Peter Smedley would probably end up more in favour of assisted suicide than not.

Surprise discovery allows scientists to block Alzheimer's

Scientists developing treatments for the devastating brain disorder Creutzfeldt-Jakob Disease (CJD) have unexpectedly blocked the onset of Alzheimer's disease, the most common cause of dementia.

Southern Cross action plan demanded

The Government was tonight coming under increasing pressure to help end uncertainty over the future of thousands of elderly residents and staff at Britain's largest care homes group.

Exile, BBC1, Sunday, Monday, Tuesday<br/>The Shadow Line, BBC2, Thursday<br/>Psychoville, BBC2, Thursday

Alzheimer's-stricken family saves an over-busy thriller, while true terror lurks with a Silent Singer

Blood test could diagnose Alzheimer's disease

Scientists have developed a blood test which they believe could diagnose Alzheimer's disease in its early stages.

Pfizer sales fall after key patents expire

Falling sales of Pfizer's key cholesterol drug, Lipitor, in the face of generic competition hit sales at the American pharmaceuticals giants in the first quarter.

The Weekend's TV: Exile, Sun, BBC1<br/>Vera, Sun, ITV1

Secrets worth investigating

Pratchett presents film on Dignitas

The author Sir Terry Pratchett is to present a documentary about the last moments of a terminally ill man who travelled to the Dignitas assisted suicide clinic to end his life.

Mary Dejevsky: Genetic testing has little value if there's no chance of a cure

If you submit to screening at, say, the age of 40, and learn that you have a predisposition to Alzheimer's, what are you supposed to do about it?

A test for Alzheimer's disease &ndash; but will anyone want to take it?

Important new insights into Alzheimer's disease have emerged from the discovery of a handful of genes that are strongly implicated in raising a person's risk of developing the brain disorder in later life.

Sleep hormone 'may reduce dementia'

Doctors are leading a new study into a drug which could improve the quality of life for people with dementia.

David Rotheray, The Troubadour, London

His name may be top of the bill, but one habit dies hard for The Beautiful South's former guitarist and tunesmith. David Rotheray continues to write songs for male and female voices, with one of each on hand tonight.

The Winstones - Bring your daughter to the slaughter

A new British horror movie casts Ray and Jaime Winstone together in a film for the first time. On set in Wales, they reveal the secrets of the family profession to Charlotte Cripps

Life and Style
Cooked up: reducing dietary animal fat might not be as healthy as government advice has led millions of people to believe
healthA look at how governments started advising incorrectly on diets
REX/Eye Candy
Neil Warnock
football'New' manager for Crystal Palace
peopleGerman paper published pictures of 18-month-old daughter
Arts and Entertainment
'A voice untroubled by time': Kate Bush
musicKate Bush set to re-enter album charts after first conerts in 35 years
Angel Di Maria poses with Louis van Gaal after signing for Manchester United
Arts and Entertainment
BBC series 'Sherlock' scooped a hat-trick of awards on the night. Benedict Cumberbatch received the award for Actor, Miniseries or Movie ('Sherlock: His Last Vow') while Martin Freeman won the award for Supporting Actor, Miniseries or Movie. Neither actor was present to collect their awards
Life and Style
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Day In a Page

Burgundy, the River Rhone & Provence – MS Swiss Corona - seven nights from £999pp
Lake Maggiore, Orta and the Matterhorn – seven nights from £899pp
Sicily – seven nights from £939pp
Pompeii, Capri and the Bay of Naples - seven nights from £799pp
Istanbul Ephesus & Troy – six nights from £859pp
Mary Rose – two nights from £319pp
Kate Bush, Hammersmith Apollo music review: A preamble, then a coup de théâtre - and suddenly the long wait felt worth it

Kate Bush shows a voice untroubled by time

A preamble, then a coup de théâtre - and suddenly the long wait felt worth it
Robot sheepdog technology could be used to save people from burning buildings

The science of herding is cracked

Mathematical model would allow robots to be programmed to control crowds and save people from burning buildings
Tyrant: Is the world ready for a Middle Eastern 'Dallas'?

This tyrant doesn’t rule

It’s billed as a Middle Eastern ‘Dallas’, so why does Fox’s new drama have a white British star?
Rachael Lander interview: From strung out to playing strings

From strung out to playing strings

Award-winning cellist Rachael Lander’s career was almost destroyed by the alcohol she drank to fight stage fright. Now she’s playing with Elbow and Ellie Goulding
The science of saturated fat: A big fat surprise about nutrition?

A big fat surprise about nutrition?

The science linking saturated fats to heart disease and other health issues has never been sound. Nina Teicholz looks at how governments started advising incorrectly on diets
Emmys 2014 review: Can they genuinely compete with the Oscars

Can they genuinely compete with the Oscars?

The recent Emmy Awards are certainly glamorous, but they can't beat their movie cousins
On the road to nowhere: A Routemaster trip to remember

On the road to nowhere

A Routemaster trip to remember
Hotel India: Mumbai's Taj Mahal Palace leaves its darker days behind

Hotel India

Mumbai's Taj Mahal Palace leaves its darker days behind
10 best pencil cases

Back to school: 10 best pencil cases

Whether it’s their first day at school, uni or a new project, treat the student in your life to some smart stationery
Arsenal vs Besiktas Champions League qualifier: Gunners know battle with Turks is a season-defining fixture

Arsenal know battle with Besiktas is a season-defining fixture

Arsene Wenger admits his below-strength side will have to improve on last week’s show to pass tough test
Pete Jenson: Athletic Bilbao’s locals-only transfer policy shows success does not need to be bought

Pete Jenson: A Different League

Athletic Bilbao’s locals-only transfer policy shows success does not need to be bought
This guitar riff has been voted greatest of all time

The Greatest Guitar Riff of all time

Whole Lotta Votes from Radio 2 listeners
Britain’s superstar ballerina

Britain’s superstar ballerina

Alicia Markova danced... every night of the week and twice on Saturdays
Berlin's Furrie invasion

Berlin's Furrie invasion

2000 fans attended Eurofeurence
‘It was a tidal wave of terror’

‘It was a tidal wave of terror’

Driven to the edge by postpartum psychosis