Travel Touch base: the portable loos on Aconcagua

The man who pays his way

Death rates drop as heart disease treatment improves

Death rates in England and Wales have fallen dramatically, by 25 per cent among men and 22 per cent among women, over the last decade, latest figures show.

The Week In Radio: Relax to arias of outstanding natural beauty

Opera is brilliant for the blood pressure. According to research, Verdi's arias, which follow musical phrases that are 10 seconds long, synchronise perfectly with the natural cardiovascular rhythm. When stroke and cardiac patients were played rousing operatic music like Puccini's Nessun Dorma, full of crescendos and diminuendos that alternately arouse and relax the body, they experienced lowered blood pressure and better outcomes.

'Magic bullet' tested to cut risk of heart attack and stroke

An international trial was launched yesterday to establish if a one-a-day pill can cut the risk of heart attacks and strokes.

'He was just so charismatic': Blair's return provokes a bout of nostalgia

The man with the Golden Tan flew to Gordon Brown's aid yesterday.

Eating chocolate 'can cut heart attack and stroke risk'

Eating just one square of chocolate a day can cut the risk of heart attack and stroke by 39%, researchers said today.

Englishman nears end of 1,000-mile race

Since a week ago last Monday, William Sichel has been running around a 1km circuit of road at a disused airport outside Athens in an attempt to become the first man in more than a decade to finish a 1,000-mile running race.

Professor Sir James Black: Nobel laureate who designed the first modern drugs for high blood pressure and peptic ulcers

Sir James Black invented the first modern blood-pressure drug, propranolol, and the first modern ulcer drug, cimetidine, which rank among the most important medical advances of the 20th century, having saved countless lives and abolished overnight the need for ulcer surgery. Sir Michael Rawlins, chairman of the National Institute for Clinical Excellence, regarded Black as "the greatest drug-hunter of the 20th century. Not only did he develop two entirely novel classes of drug, beta-blockers and H2 antagonists, which had a major impact; but he also introduced a unique approach to drug discovery by using agonists as the starting point for the development of specific antagonists."

Surgical safety: 'Without this checklist, I would have killed a man'

A simple but effective safety test should be implemented in all hospitals from today. The surgeon behind it, Atul Gawande, describes how it helped him avert a medical catastrophe

Can you be fit and obese?

Kick boxing twice a week, walking the dog two miles every day – Clint Witchalls thought he was healthy. Then a visit to the doctor revealed he was dangerously overweight...

Mystery surrounds poisoning of doctor who exposed torture

Iranian medic 'was given fatal overdose in a portion of salad'

Madame Verona Comes Down the Hill, By Dimitri Verhulst

Sombre tale hits the high spots

'Healthy' sweetener linked to high blood pressure

An ingredient in processed foods and soft drinks could be a recipe for high blood pressure, research suggests.

Jeremy Laurance: A breakthrough – but the real answer lies in exercise and diet

The first of a new class of slimming pill is bound to attract attention, especially when it comes with the backing of a leading obesity researcher and is published in an internationally respected medical journal.

Anti-obesity drug takes off a stone in 20 weeks

New treatment performs better than rivals and without the side effects
Life and Style
A monstrous idea? Body transplants might no longer be science fiction
Science An Italian neurosurgeon believes so - and it's not quite as implausible as it sounds, says Steve Connor
Sport
Demba Ba (right) celebrates after Besiktas win on penalties
footballThere was no happy return to the Ataturk Stadium, where the Reds famously won Champions League
Arts and Entertainment
Natural beauty: Aidan Turner stars in the new series of Poldark
arts + ents
News
Mia Freedman, editorial director of the Mamamia website, reads out a tweet she was sent.
arts + ents
News
people
Arts and Entertainment
The write stuff: masters of story-telling James Joyce, left, and Thomas Hardy
arts + ents...begging to differ, John Walsh can't even begin to number the ways
News
Image from a flyer at the CPAC event where Nigel Farage will be speaking
news
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Day In a Page

Independent Travel
Pompeii, Capri & the Bay of Naples
Seven Cities of Italy
Burgundy, the River Rhone & Provence
Prague, Budapest and Vienna
Lake Garda
3.	Provence 6 nights B&B by train from £599pp
Prices correct as of 20 February 2015
HIV pill: Scientists hail discovery of 'game-changer' that cuts the risk of infection among gay men by 86%

Scientists hail daily pill that protects against HIV infection

Breakthrough in battle against global scourge – but will the NHS pay for it?
How we must adjust our lifestyles to nature: Welcome to the 'Anthropocene', the human epoch

Time to play God

Welcome to the 'Anthropocene', the human epoch where we may need to redefine nature itself
MacGyver returns, but with a difference: Handyman hero of classic 1980s TV series to be recast as a woman

MacGyver returns, but with a difference

Handyman hero of classic 1980s TV series to be recast as a woman
Tunnel renaissance: Why cities are hiding roads down in the ground

Tunnel renaissance

Why cities are hiding roads underground
'Backstreet Boys - Show 'Em What You're Made Of': An affectionate look at five middle-aged men

Boys to men

The Backstreet Boys might be middle-aged, married and have dodgy knees, but a heartfelt documentary reveals they’re not going gently into pop’s good night
Crufts 2015: Should foreign dogs be allowed to compete?

Crufts 2015

Should foreign dogs be allowed to compete?
10 best projectors

How to make your home cinema more cinematic: 10 best projectors

Want to recreate the big-screen experience in your sitting room? IndyBest sizes up gadgets to form your film-watching
Manchester City 1 Barcelona 2 player ratings: Luis Suarez? Lionel Messi? Joe Hart? Who was the star man?

Manchester City vs Barcelona player ratings

Luis Suarez? Lionel Messi? Joe Hart? Who was the star man at the Etihad?
Arsenal vs Monaco: Monaco - the making of Gunners' manager Arsene Wenger

Monaco: the making of Wenger

Jack Pitt-Brooke speaks to former players and learns the Frenchman’s man-management has always been one of his best skills
Cricket World Cup 2015: Chris Gayle - the West Indies' enigma lives up to his reputation

Chris Gayle: The West Indies' enigma

Some said the game's eternal rebel was washed up. As ever, he proved he writes the scripts by producing a blistering World Cup innings
In Ukraine a dark world of hybrid warfare and murky loyalties prevails

In Ukraine a dark world of hybrid warfare

This war in the shadows has been going on since the fall of Mr Yanukovych
'Birdman' and 'Bullets Over Broadway': Homage or plagiarism?

Homage or plagiarism?

'Birdman' shares much DNA with Woody Allen's 'Bullets Over Broadway'
Broadchurch ends as damp squib not even David Tennant can revive

A damp squib not even David Tennant can revive

Broadchurch, Series 2 finale, review
A Koi carp breeding pond, wall-mounted iPads and a bathroom with a 'wellness' shower: inside the mansion of Germany's 'Bishop of Bling'

Inside the mansion of Germany's 'Bishop of Bling'

A Koi carp breeding pond, wall-mounted iPads and a bathroom with a 'wellness' shower