Angelina Jolie went back to work just four days after her double mastectomy

Earlier this week, Oscar-winning actress Angelina Jolie revealed that she’d had a double mastectomy after discovering she carried the BRCA 1 gene

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Among them will be 60 runners attempting to set an array of Guinness World Records – including Jerome Timbrell who hopes to complete the fastest marathon as a mascot while dressed as a fire extinguisher

2012 all over again: London Marathon's search for the Olympic spirit

As well as showing solidarity with Boston, the race will revive last year's feel good factor

Plaintiffs arrive for the start of the trial at an improvised courthouse

Breast implants court case: 5,000 women lift French trial to a scale never seen before

Breast implant firm’s founder faces fraud charge alongside four colleagues

Anna Friel, Steve Coogan, Tamsin Egerton and Chris Addison arriving at the UK premiere of The Look of Love at the Curzon Soho, London.

'Someone had to do it' - Steve Coogan admits to strip club research for The Look Of Love

Steve Coogan tonight admitted he visited a lot of strip clubs to research his latest role as porn baron Paul Raymond.

Men could receive routine saliva test for prostate cancer within five years

Breakthrough? Scientists unveil the 'single biggest leap forward' in tackling prostate cancer

Men could receive routine saliva test within five years, after pan-European research

Anastacia is suffering from breast cancer

Anastacia cancels Dubai gig and European tour after second breast cancer diagnosis

Singer Anastacia has cancelled a scheduled performance in Dubai as well as an upcoming European tour after being diagnosed with breast cancer  for a second time.

Modern approaches to cancer therapy are based on diagnosing the disease at the level of the DNA. Drugs, such as Herceptin, can then be targeted at those patients with a particular genetic profile. This can produce better results as well as eliminating unnecessary therapy in patients who would otherwise not respond to treatment

Forensic cancer treatment: Personalised drugs therapy becoming a reality with hopes for improvement in survival rates

A decade ago it took tens of millions of pounds and many years to sequence the compete genome of one individual. Now it takes a few hundred pounds and a couple of days to decode the entire DNA of a cancer cell.

A radiologist examines mammograms on a lightbox

Women with a family history of breast cancer could be offered preventative medication under new NHS plans

Around half a million women with a strong family history of breast cancer should be offered drugs to prevent the disease from developing, according to official advice issued today.

A radiologist examines mammograms on a lightbox

Scientists 'put positive spin' on breast cancer studies

Scientists involved in breast cancer research tend to exaggerate the positives and underplay the negatives of their findings, a new study suggests.

Mother jailed for life for beating son to death because he failed to learn Koran by heart

Sara Ege was ordered to serve a minimum of 17 years and collapsed as the sentence was delivered

Drugs ban for javelin man Ian Burns

A javelin thrower and coach has been banned from all competition for four years for possessing numerous banned substances discovered after a raid by police.

A black-and-white photograph issued courtesy of Sands (Stillbirth and neonatal death charity) of Natasha and Kent Fermor, from Coventry, with their baby son Lucas, who died after medics failed to spot he was being starved of oxygen during labour

Hospital apologises over death of new-born baby

A hospital trust has apologised to the parents of a baby who died after medics failed to spot he was being starved of oxygen during labour.

Liberty X's Michelle Heaton speaks of mastectomy 'hell'

Former Liberty X star Michelle Heaton said there was "light at the end of the tunnel" after having a double mastectomy in a bid to avoid developing breast cancer.

Fancy Intense Pink Diamond and Diamond Ring, Oscar Heyman & Brothers sold for $8,594,500

Huge price tag can't take shine off some extra special jewels

The Occupy movement may have run out of steam since its apex of publicity this summer, but the $65million proceeds of a jewels auction at Sotheby's in New York on Wednesday is proof that the great divide still exists.

Lab mice can't help us in the fight against cancer

Curing cancer in mice is unlikely to lead to a breakthrough for humans. So why do we persist in carrying out bizarre and freakish experiments?

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Johnny Marr talks relationships and reunions

He's worked with Modest Mouse, the Pet Shop Boys and Beck, to name a few, and recently released his first solo album. So why, wonders Johnny Marr, do people still hark on about The Smiths?
After the flood: From Haiti to Britain, one man has captured the devastation of our increasingly deluged lands

In pictures: After the flood

From Haiti to Britain, one man has captured the devastation of our increasingly deluged lands
Death becomes her: Meet the very modern mortician who champions 'cool' funerals

Death becomes her: A very modern mortician

Ever considered baking a loved one's remains into a cake or putting their ashes in fireworks? If so, talk to Caitlin Doughty, champion of the alternative death industry.
How long can the 'Keep Calm' trend carry on?

How long can the 'Keep Calm' trend carry on?

At first it seemed clever and cute. Then the 'Keep Calm' motif went mad, spawning endless offshoots.
The man who built Brum: A lament for the demise of John Madin's Brutalist Birmingham

John Madin: The man who built Brum

The architect's buildings were supposed to leave an indelible, futuristic mark on his beloved hometown but they are now being inexorably torn down.
School of chop: Learning the art of butchery at the Ginger Pig

School of chop: Learning the art of butchery

How do you butcher a lamb? Or make Mexican street food in a British kitchen? Christopher Hirst finds out.
James Pembroke: The man who's eaten everywhere

The man who's eaten everywhere

Few people know more about restaurants than James Pembroke, who only spent five mealtimes at home during his entire childhood.
A Berliner in 1963 – but did John F Kennedy once admire Adolf Hitler?

A Berliner in 1963 – but did John F Kennedy once admire Adolf Hitler?

The young JFK praised 'superior' Nordic races during visits to Germany
Banned Iranian director Mohammad Rasoulof to attend Cannes Film Festival 2013, his first public appearance since prison

Banned Iranian director to attend Cannes Film Festival

Mohammad Rasoulof to make his first public appearance since being imprisoned three years ago
Seeing the larger picture: Inspiring images of space

Seeing the larger picture: Inspiring images of space

An exhibition explores images how photography has shaped astronomy
Eat Spam and carry on: Wartime pamphlets could teach us a thing or two about healthy, thrifty eating

Eat Spam and carry on

Wartime pamphlets could teach us a thing or two about healthy, thrifty eating
Facial hair: Cat beards and the purrrsuit of excellence

Facial hair

Cat beards and the purrrsuit of excellence
The 10 Best salt and pepper sets

The 10 Best salt and pepper sets

Whether they're for everyday use or to make your dining table look just right, it's worth getting a stylish shaker...
Ferran Soriano: Predicting success if Manchester City 'vision' is followed

Ferran Soriano: Predicting success if Manchester City 'vision' is followed

Chief executive says trophies will come if a 'core' of suitable players is in place
Thomas Müller: We couldn't handle losing a Champions League Final again

Thomas Müller: We couldn't handle losing a Champions League Final again

The Bayern Munich forward tells Tim Rich his side have to shed chokers' tag after two recent final defeats