i Philip Pullman, author

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Leading article: Just the start in tackling dementia

It is absolutely right that the Government is to double the spending on research into dementia. The disease is spreading so fast that there will soon be more than a million sufferers in the UK. And treating Alzheimer's, and similar problems, is already costing the NHS £23bn a year – more than cancer, heart disease or strokes.

David Cameron vows to double dementia funding

Funding for research into dementia is to be more than doubled by 2015 in a bid to make Britain a world leader in the field, David Cameron announced today.

Best Friends: Rob Brydon and Steve Coogan exchange confidences and laughter in The Trip, and we love to listen in

The Listening Project: Yes, it's good to talk. But the real joy is in being allowed to listen

As the BBC airs intimate conversations, project deviser Tony Phillips finds he is deeply moved

Alzheimer’s treatment in late stages of disease does slow progression

More than 100,000 people in the UK suffering the “savage” effects of advanced Alzheimer’s disease could benefit from drug treatment to slow its progression.

Chemical link revealed in Alzheimer's study

Alzheimer's symptoms such as memory loss could be prevented by targeting a chemical that dismantles brain connections, research suggests.

Ex-care workers jailed for thefts

Two former care home workers who "fleeced" vulnerable patients of tens of thousands of pounds were jailed today.

New York Philharmonic Orchestra/ Gilbert, Barbican Hall

For the New York Philharmonic to have embarked upon a London residency without Mahler in their portfolio would have been unconscionable.

Cash crisis slows justice for the vulnerable at Court of Protection

Hundreds of vulnerable people seeking court decisions about where they live or whom they can meet could experience months of delays because the government expert protecting their interests has almost run out of money, The Independent can disclose.

Switzerland's 'Dementiaville' designed to mirror the past

Plan to build 1950s-style village for Alzheimer's sufferers divides geriatric-care experts

Brief encounter: Jonathan Brown wears distorting glasses, noisy headphones and neoprene mittens to experience what life is like for people living with dementia

Dementia: A small taste of hell on earth

Dementia affects hundreds of thousands of people in the UK, yet few know how it feels. A new awareness course aims to help us to find out

Superficially similar, but the Iron Lady had a quality that Streep lacks

Iron Lady film made too soon, says David Cameron

David Cameron today stepped in to the row over the Iron Lady, claiming the film should have been made "another day".

Oscar winner Meryl Streep, left, transformed for her role as former Prime Minister Margaret Thatcher, right

Portrait too blue to be true

There is one very good reason to see The Iron Lady, perhaps good enough to neutralise the reasons to feel annoyed by it. Meryl Streep as Margaret Thatcher gives a performance of uncanny exactitude and command that overleaps the bounds of mimicry: despite a face encrusted with prosthetics and make-up, Streep somehow conveys through outward presentation (clothes, hair, voice) the inward drive of her personality. Strictly as an impersonation it will be seen as definitive for years to come.

The Iron Lady (12A)

Starring: Meryl Streep, Richard E Grant, Jim Broadbent, Anthony Head

Among those aged 45-49, there was a 3.6 per cent decline in mental reasoning over the next 10 years

Life ends at 45... Study reveals when our mental powers start to diminish

Huge survey carried out on Whitehall civil servants shows our brains peak earlier that we think

Leading article: An issue of dignity that can no longer be avoided

Even with all the benefits of medicine, the terminally ill may face extreme pain and indignity
News
video... and it wasn't good news for many of them
News
New documents from the late Robin Williams' estate stipulate a restriction on his image, or any likeness of it, being used until 2039
people
Sport
Chelsea
football
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people Ex-wife of John Lennon has died at her home in Spain
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Nick Clegg on the campaign trail in Glasgow on Wednesday; he says education is his top priority
peopleNick Clegg remains optimistic despite dismal Lib Dem poll ratings
Arts and Entertainment
Buttoned up: Ryan Reynolds with Helen Mirren in ‘Woman in Gold’
filmFor every box-office smash in his Hollywood career, there's always been a misconceived let-down. Now he says it's time for a reboot
News
people
News
Actress Julianne Moore wins the Best Actress in a Leading Role Award for 'Still Alice' during the 87th Annual Academy Awards in Hollywood, California
people
Sport
Ross Barkley
footballPaul Scholes says it's time for the Everton playmaker to step up and seize the England No 10 shirt
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'We will fix it': mice in the 1970s children’s programme Bagpuss
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Pompeii, Capri & the Bay of Naples
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War with Isis: Iraq declares victory in the battle for Tikrit - but militants make make ominous advances in neighbouring Syria's capital

War with Isis

Iraq declares victory in the battle for Tikrit - but militants make make ominous advances in neighbouring Syria
Scientists develop mechanical spring-loaded leg brace to improve walking

A spring in your step?

Scientists develop mechanical leg brace to help take a load off
Peter Ackroyd on Alfred Hitchcock: How London shaped the director's art and obsessions

Peter Ackroyd on Alfred Hitchcock

Ackroyd has devoted his literary career to chronicling the capital and its characters. He tells John Walsh why he chose the master of suspense as his latest subject
Ryan Reynolds interview: The actor is branching out with Nazi art-theft drama Woman in Gold

Ryan Reynolds branches out in Woman in Gold

For every box-office smash in Ryan Reynolds' Hollywood career, there's always been a misconceived let-down. It's time for a rethink and a reboot, the actor tells James Mottram
Why Robin Williams safeguarded himself against a morbid trend in advertising

Stars safeguard against morbid advertising

As film-makers and advertisers make increasing posthumous use of celebrities' images, some stars are finding new ways of ensuring that they rest in peace
The UK horticulture industry is facing a skills crisis - but Great Dixter aims to change all that

UK horticulture industry facing skills crisis

Great Dixter manor house in East Sussex is encouraging people to work in the industry by offering three scholarships a year to students, as well as generous placements
Hack Circus aims to turn the rule-abiding approach of TED talks on its head

Hack Circus: Technology, art and learning

Hack Circus aims to turn the rule-abiding approach of TED talks on its head. Rhodri Marsden meets mistress of ceremonies Leila Johnston
Sevenoaks is split over much-delayed decision on controversial grammar school annexe

Sevenoaks split over grammar school annexe

If Weald of Kent Grammar School is given the go-ahead for an annexe in leafy Sevenoaks, it will be the first selective state school to open in 50 years
10 best compact cameras

A look through the lens: 10 best compact cameras

If your smartphone won’t quite cut it, it’s time to invest in a new portable gadget
Paul Scholes column: Ross Barkley played well against Italy but he must build on that. His time to step up and seize that England No 10 shirt is now

Paul Scholes column

Ross Barkley played well against Italy but he must build on that. His time to step up and seize that England No 10 shirt is now
Why Michael Carrick is still proving an enigma for England

Why Carrick is still proving an enigma for England

Manchester United's talented midfielder has played international football for almost 14 years yet, frustratingly, has won only 32 caps, says Sam Wallace
Tracey Neville: The netball coach who is just as busy as her brothers, Gary and Phil

Tracey Neville is just as busy as her brothers, Gary and Phil

The former player on how she is finding time to coach both Manchester Thunder in the Superleague and England in this year's World Cup
General Election 2015: The masterminds behind the scenes

The masterminds behind the election

How do you get your party leader to embrace a message and then stick to it? By employing these people
Machine Gun America: The amusement park where teenagers go to shoot a huge range of automatic weapons

Machine Gun America

The amusement park where teenagers go to shoot a huge range of automatic weapons
The ethics of pet food: Why are we are so selective in how we show animals our love?

The ethics of pet food

Why are we are so selective in how we show animals our love?