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Mark Parisi participates in medical trials that can pay five figure sums

Letter: Cocaine snorting

I THOUGHT I must be seeing things when I read the matter-of-fact description of coke snorting in "The Diary of Emma D May" (Real Life, 10 May). Will the Independent on Sunday soon be supporting the legalisation of this drug, too?

Letter: Bitter pill

Anyone considering taking Roaccutane for severe acne ("Skin diseases drive sufferers to suicide", 21 September) should fully understand what its side-effects are first.

Letter: Say please

I agree that arrogant service can ruin a meal ("Humiliation..." Real Life, 27 July). But please also remember that staff often have to deal with rude and arrogant customers whose demands and behaviour are unreasonable. Waiters are ordinary people. I have always found in restaurants all over the world that if I am pleasant and reasonable to the restaurant staff they will be pleasant in return. A smile and a compliment works wonders.

Letter: No pill to cure unhappiness

Sir: Andrew Brown's article "Let them eat Prozac" (5 July) was another example of ignorance about mental illness. He talks about Prozac as if it was a recreational drug that can get one high. Antidepressants relieve symptoms of clinical depression - which has nothing to do with unhappiness. Unhappiness is part of the human condition and does not respond to antidepressant drugs. People seek relief more and more from unhappiness through the use of recreational drugs, most of which are known to be dangerous. Clinical depression, however, is a potentially life-threatening illness.

Letter: Ecstatic roulette

Sir: George Howarth (letter, 28 June) asserts that "Drugs destroy lives ... taking an Ecstasy tablet is like playing Russian roulette". Is Russian roulette actually illegal?

New hormone drug to cheer flagging libido

A new hormone replacement therapy being developed by a British company could be the answer to flagging libido in middle-aged men, it was claimed yesterday, writes Magnus Grimond.

Baker takes Medeva chair

Baker takes Medeva chair

LETTER:Ecstasy and Prozac: the facts

From Professor Hugh Freeman

SB alters drug tests

SmithKline Beecham said it has stopped administering placebos in two US trials on its carvedilol heart drug because tests have shown the drug is "unexpectedly" effective in reducing death rates.

Zantac on sale over counter

Glaxo has won approval for over-the-counter sales of its best-selling drug, Zantac, in Britain. The drug, which relieves the symptoms of heartburn and dyspepsia, will be on sale within the first quarter of this year, marketed through Glaxo's alli ance with Warner Wellcome.

1m pounds drugs haul

DETECTIVES in the Cardiff area today seized a haul of amphetamine sulphate drugs with an estimated street value of around pounds 1m.

PM rules out VAT on food

Mr Major gave his most unequivocal pledge that VAT would not be put on food by saying in the Commons that he could 'conceive of no circumstances ever when food would be subject to VAT'.

Drug kit success

A company selling home testing kits which check whether children have been taken drugs such as Ecstasy said it sold 1,200 within two weeks. The kits, which test urine samples, contain small indicator discs which change colour.

Food poison fear

More than 40 people suffered food poisoning in an outbreak which may have killed a girl, two. A West Lothian dairy was the suspected source.

Glasgow drug toll reaches 30

TWO more drug users have been found dead in Glasgow, bringing the number of drug-related deaths in the city to 30 so far this year. No common factor has been found linking the deaths, which have involved different types of drugs.
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The drugs revolution starts now as MPs agree its high time for change

The drugs revolution starts now as MPs agree its high time for change

Commons debate highlights growing cross-party consensus on softening UK drugs legislation, unchanged for 43 years
The camera is turned on tabloid editors in Richard Peppiatt's 'One Rogue Reporter'

Gotcha! The camera is turned on tabloid editors

Hugh Grant says Richard Peppiatt's 'One Rogue Reporter' documentary will highlight issues raised by Leveson
Fall of the Berlin Wall: It was thanks to Mikhail Gorbachev that this symbol of division fell

Fall of the Berlin Wall

It was thanks to Gorbachev that this symbol of division fell
Halloween 2014: What makes Ouija boards, demon dolls, and evil clowns so frightening?

What makes ouija boards and demon dolls scary?

Ouija boards, demon dolls, evil children and clowns are all classic tropes of horror, and this year’s Halloween releases feature them all. What makes them so frightening, decade after decade?
A safari in modern Britain: Rose Rouse reveals how her four-year tour of Harlesden taught her as much about the UK as it did about NW10

Rose Rouse's safari in modern Britain

Rouse decided to walk and talk with as many different people as possible in her neighbourhood of Harlesden and her experiences have been published in a new book
Welcome to my world of no smell and odd tastes: How a bike accident left one woman living with unwanted food mash-ups

'My world of no smell and odd tastes'

A head injury from a bicycle accident had the surprising effect of robbing Nell Frizzell of two of her senses

Matt Parker is proud of his square roots

The "stand-up mathematician" is using comedy nights to preach maths to big audiences
Paul Scholes column: Beating Manchester City is vital part of life at Manchester United. This is first major test for Luke Shaw, Angel Di Maria and Radamel Falcao – it’s not a game to lose

Paul Scholes column

Beating City is vital part of life at United. This is first major test for Shaw, Di Maria and Falcao – it’s not a game to lose
Frank Warren: Call me an old git, but I just can't see that there's a place for women’s boxing

Frank Warren column

Call me an old git, but I just can't see that there's a place for women’s boxing
Adrian Heath interview: Former Everton striker prepares his Orlando City side for the MLS - and having Kaka in the dressing room

Adrian Heath's American dream...

Former Everton striker prepares his Orlando City side for the MLS - and having Kaka in the dressing room
Simon Hart: Manchester City will rise again but they need to change their attitude

Manchester City will rise again but they need to change their attitude

Manuel Pellegrini’s side are too good to fail and derby allows them to start again, says Simon Hart
Isis in Syria: A general reveals the lack of communication with the US - and his country's awkward relationship with their allies-by-default

A Syrian general speaks

A senior officer of Bashar al-Assad’s regime talks to Robert Fisk about his army’s brutal struggle with Isis, in a dirty war whose challenges include widespread atrocities
‘A bit of a shock...’ Cambridge economist with Glasgow roots becomes Zambia’s acting President

‘A bit of a shock...’ Economist with Glasgow roots becomes Zambia’s acting President

Guy Scott's predecessor, Michael Sata, died in a London hospital this week after a lengthy illness
Fall of the Berlin Wall: History catches up with Erich Honecker - the East German leader who praised the Iron Curtain and claimed it prevented a Third World War

Fall of the Berlin Wall

History catches up with Erich Honecker - the East German leader who praised the Iron Curtain and claimed it prevented a Third World War
How to turn your mobile phone into easy money

Turn your mobile phone into easy money

There are 90 million unused mobiles in the UK, which would be worth £7bn if we cashed them in, says David Crookes