Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

Diet has long informed how society perceives weight and body image

In the last 50 years our diet has been transformed. From boiled beef and carrots to a Big Mac and fries, we have moved from a world of shortages and post-war rationing to one of overabundance.

The moai, giant stone statues that line the Easter Island coast

This week's big questions: Can ancient tribes teach us anything? Are we doomed, like Easter Islanders, to extinction?

This week's questions are answered by Jared Diamond, an American scientist and the author of the bestselling ‘Guns, Germs, and Steel

Spencer Cox: Activist who helped bring an anti-Aids drug on to the market

Spencer Cox, who died in New York of Aids-related causes on 18 December aged 44, was an Aids activist who helped form an organisation to boost treatment research and recently appeared in a documentary about an Aids coalition.

Sir Ian McKellen was memerising in his reading of The Prelude by Wordsworth

Sir Ian McKellen speaks of prostate cancer shock

Sir Ian McKellen has told how he feared the worst when he was diagnosed with prostate cancer.

Anne Hathaway has tried extreme – and extremely unpleasant – eating regimes to lose weight for a part

Hollywood roles to diet for

If you find it hard to lose weight, be glad you're not an actor. Playing an emaciated waif can mean mad, bad and dangerous eating plans, says Gillian Orr

Books of the Year 2012: Celebrity

From art to sport, poetry to nature, travel to food, history to music: our writers select the best of the year’s books in a comprehensive guide to the highlights in every shade of the literary spectrum – except grey

David Cecil in a Kampala court cell after his arrest earlier this month

Together the voices of reason and care can bring sexual equality to an ever more draconian Uganda

Our writer, who saw an unlikely champion of gay rights fight for his beliefs in an African court, says that there are grounds for optimism in the battle for equality there

World AIDS Day: Health problems do not discriminate based on where people live

It's not just low income countries that have a problem.

Editorial: Aids treatment is a success story, but more must be done

In 2000, a year's course of anti-retroviral drugs cost $10,000 and projections caused consternation even in Western countries coping with a few thousand cases of HIV. The idea that treatment might be rolled out to millions in the developing world seemed a pipe dream.

Elderly women in Kasarika, a village with one of the highest rates of HIV in Malawi

World Aids Day: The curse of being one of the witches of Malawi

An Aids awareness scheme is teaching villagers HIV is an illness, and not caused by witchcraft. By Hazel Southam in Kasarika

A torch light rally is held in Kolkata yesterday ahead of World Aids Day

World Aids Day: ‘Turning the tide will fail if funding is not increased’

Three decades on from the start of the Aids pandemic, the main global agencies are uncertain whether to be cheerful or gloomy about prospects for the worst disease of modern times .

Patient co-ordinator Chris is one of the longest living survivors of HIV in Britain

World Aids Day: Suddenly I had a future, the relief was immense

Patient co-ordinator Chris is one of the longest living survivors of HIV in Britain. He speaks to Patrick Strudwick

World Aids Day: I met Enoch. Three years ago he couldn't stand up. Now his life is transformed. The cost? 23p a day

I choose not to listen to the cynics, whose philosophical opposition to aid bewilders me

World AIDS Day: A race against time as HIV treatment is cut

Anti-retrovirals are vital in improving and saving the lives of children with HIV.

The Vivisector: Group show curated by Todd Levin, Sprüth Magers, London

A naked doll with long synthetic hair greets the visitor to this inspired exhibition, which explores "the idea of opening up and exposing a living body".

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Day In a Page

Burgundy, the River Rhone & Provence – MS Swiss Corona - seven nights from £999pp
Lake Maggiore, Orta and the Matterhorn – seven nights from £899pp
Sicily – seven nights from £939pp
Pompeii, Capri and the Bay of Naples - seven nights from £799pp
Istanbul Ephesus & Troy – six nights from £859pp
Mary Rose – two nights from £319pp
Save the tiger: The animals bred for bones on China’s tiger farms

The animals bred for bones on China’s tiger farms

The big cats kept in captivity to perform for paying audiences and then, when dead, their bodies used to fortify wine
A former custard factory, a Midlands bog and a Leeds cemetery all included in top 50 hidden spots in the UK

A former custard factory, a Midlands bog and a Leeds cemetery

Introducing the top 50 hidden spots in Britain
Ebola epidemic: Plagued by fear

Ebola epidemic: Plagued by fear

How a disease that has claimed fewer than 2,000 victims in its history has earned a place in the darkest corner of the public's imagination
Chris Pratt: From 'Parks and Recreation' to 'Guardians of the Galaxy'

From 'Parks and Recreation' to 'Guardians of the Galaxy'

He was homeless in Hawaii when he got his big break. Now the comic actor Chris Pratt is Hollywood's new favourite action star
How live cinema screenings can boost arts audiences

How live cinema screenings can boost arts audiences

Broadcasting plays and exhibitions to cinemas is a sure-fire box office smash
Shipping container hotels: Pop-up hotels filling a niche

Pop-up hotels filling a niche

Spending the night in a shipping container doesn't sound appealing, but these mobile crash pads are popping up at the summer's biggest events
Native American headdresses are not fashion accessories

Feather dust-up

A Canadian festival has banned Native American headwear. Haven't we been here before?
Boris Johnson's war on diesel

Boris Johnson's war on diesel

11m cars here run on diesel. It's seen as a greener alternative to unleaded petrol. So why is London's mayor on a crusade against the black pump?
5 best waterproof cameras

Splash and flash: 5 best waterproof cameras

Don't let water stop you taking snaps with one of these machines that will take you from the sand to meters deep
Louis van Gaal interview: Manchester United manager discusses tactics and rebuilding after the David Moyes era

Louis van Gaal interview

Manchester United manager discusses tactics and rebuilding after the David Moyes era
Will Gore: The goodwill shown by fans towards Alastair Cook will evaporate rapidly if India win the series

Will Gore: Outside Edge

The goodwill shown by fans towards Alastair Cook will evaporate rapidly if India win the series
The children were playing in the street with toy guns. The air strikes were tragically real

The air strikes were tragically real

The children were playing in the street with toy guns
Boozy, ignorant, intolerant, but very polite – The British, as others see us

Britain as others see us

Boozy, ignorant, intolerant, but very polite
How did our legends really begin?

How did our legends really begin?

Applying the theory of evolution to the world's many mythologies
Watch out: Lambrusco is back on the menu

Lambrusco is back on the menu

Naff Seventies corner-shop staple is this year's Aperol Spritz