Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

Diet has long informed how society perceives weight and body image

In the last 50 years our diet has been transformed. From boiled beef and carrots to a Big Mac and fries, we have moved from a world of shortages and post-war rationing to one of overabundance.

The moai, giant stone statues that line the Easter Island coast

This week's big questions: Can ancient tribes teach us anything? Are we doomed, like Easter Islanders, to extinction?

This week's questions are answered by Jared Diamond, an American scientist and the author of the bestselling ‘Guns, Germs, and Steel

Spencer Cox: Activist who helped bring an anti-Aids drug on to the market

Spencer Cox, who died in New York of Aids-related causes on 18 December aged 44, was an Aids activist who helped form an organisation to boost treatment research and recently appeared in a documentary about an Aids coalition.

Sir Ian McKellen was memerising in his reading of The Prelude by Wordsworth

Sir Ian McKellen speaks of prostate cancer shock

Sir Ian McKellen has told how he feared the worst when he was diagnosed with prostate cancer.

Anne Hathaway has tried extreme – and extremely unpleasant – eating regimes to lose weight for a part

Hollywood roles to diet for

If you find it hard to lose weight, be glad you're not an actor. Playing an emaciated waif can mean mad, bad and dangerous eating plans, says Gillian Orr

Books of the Year 2012: Celebrity

From art to sport, poetry to nature, travel to food, history to music: our writers select the best of the year’s books in a comprehensive guide to the highlights in every shade of the literary spectrum – except grey

David Cecil in a Kampala court cell after his arrest earlier this month

Together the voices of reason and care can bring sexual equality to an ever more draconian Uganda

Our writer, who saw an unlikely champion of gay rights fight for his beliefs in an African court, says that there are grounds for optimism in the battle for equality there

World AIDS Day: Health problems do not discriminate based on where people live

It's not just low income countries that have a problem.

Editorial: Aids treatment is a success story, but more must be done

In 2000, a year's course of anti-retroviral drugs cost $10,000 and projections caused consternation even in Western countries coping with a few thousand cases of HIV. The idea that treatment might be rolled out to millions in the developing world seemed a pipe dream.

Elderly women in Kasarika, a village with one of the highest rates of HIV in Malawi

World Aids Day: The curse of being one of the witches of Malawi

An Aids awareness scheme is teaching villagers HIV is an illness, and not caused by witchcraft. By Hazel Southam in Kasarika

A torch light rally is held in Kolkata yesterday ahead of World Aids Day

World Aids Day: ‘Turning the tide will fail if funding is not increased’

Three decades on from the start of the Aids pandemic, the main global agencies are uncertain whether to be cheerful or gloomy about prospects for the worst disease of modern times .

Patient co-ordinator Chris is one of the longest living survivors of HIV in Britain

World Aids Day: Suddenly I had a future, the relief was immense

Patient co-ordinator Chris is one of the longest living survivors of HIV in Britain. He speaks to Patrick Strudwick

World Aids Day: I met Enoch. Three years ago he couldn't stand up. Now his life is transformed. The cost? 23p a day

I choose not to listen to the cynics, whose philosophical opposition to aid bewilders me

World AIDS Day: A race against time as HIV treatment is cut

Anti-retrovirals are vital in improving and saving the lives of children with HIV.

The Vivisector: Group show curated by Todd Levin, Sprüth Magers, London

A naked doll with long synthetic hair greets the visitor to this inspired exhibition, which explores "the idea of opening up and exposing a living body".

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Seifeddine Rezgui: What motivated a shy student to kill 38 holidaymakers in Tunisia?

Making of a killer

What motivated a shy student to kill 38 holidaymakers in Tunisia?
UK Heatwave: Temperatures on the tube are going to exceed the legal limit for transporting cattle

Just when you thought your commute couldn't get any worse...

Heatwave will see temperatures on the Tube exceed legal limit for transporting cattle
Exclusive - The Real Stories of Migrant Britain: Swapping Bucharest for London

The Real Stories of Migrant Britain

Meet the man who swapped Romania for the UK in a bid to provide for his family, only to discover that the home he left behind wasn't quite what it seemed
Cheaper energy on the way, but it's not all sunshine and rainbows

Cheaper energy on the way, but it's not all sunshine and rainbows

Solar power will help bring down electricity prices over the next five years, according to a new report. But it’s cheap imports of ‘dirty power’ that will lower them the most
Katy Perry prevented from buying California convent for $14.5m after nuns sell to local businesswoman instead

No grace of God for Katy Perry as sisters act to stop her buying convent

Archdiocese sues nuns who turned down star’s $14.5m because they don’t approve of her
Ajmer: The ancient Indian metropolis chosen to be a 'smart city' where residents would just be happy to have power and running water

Residents just want water and power in a city chosen to be a ‘smart’ metropolis

The Indian Government has launched an ambitious plan to transform 100 of its crumbling cities
Michael Fassbender in 'Macbeth': The Scottish play on film, from Welles to Cheggers

Something wicked?

Films of Macbeth don’t always end well - just ask Orson Welles... and Keith Chegwin
10 best sun creams for body

10 best sun creams for body

Make sure you’re protected from head to toe in the heatwave
Wimbledon 2015: Nick Bollettieri - Milos Raonic has ability to get to the top but he must learn to handle pressure in big games

Nick Bollettieri's Wimbledon files

Milos Raonic has ability to get to the top but he must learn to handle pressure in big games
Women's World Cup 2015: How England's semi-final success could do wonders for both sexes

There is more than a shiny trophy to be won by England’s World Cup women

The success of the decidedly non-famous females wearing the Three Lions could do wonders for a ‘man’s game’ riddled with cynicism and greed
How to stop an asteroid hitting Earth: Would people co-operate to face down a global peril?

How to stop an asteroid hitting Earth

Would people cooperate to face a global peril?
Just one day to find €1.6bn: Greece edges nearer euro exit

One day to find €1.6bn

Greece is edging inexorably towards an exit from the euro
New 'Iron Man' augmented reality technology could help surgeons and firefighters, say scientists

'Iron Man' augmented reality technology could become reality

Holographic projections would provide extra information on objects in a person's visual field in real time
Sugary drinks 'are killing 184,000 adults around the world every year'

Sugary drinks are killing 184,000 adults around the world every year

The drinks that should be eliminated from people's diets
Pride of Place: Historians map out untold LGBT histories of locations throughout UK

Historians map out untold LGBT histories

Public are being asked to help improve the map