Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

The Care Quality Commission (CQC) has announced a national review of dementia care

G8 Dementia Summit: PM pledges to double funding for research by 2025

While GlaxoSmithKline announces £200m of investment to set up a 'centre of excellence' that will turn breakthroughs in the lab into effective drugs

Jacob Zuma was greeted with hostility in Soweto

Nelson Mandela memorial: The booing of Jacob Zuma shows that divisions still remain

In front of leaders from around the world, South Africa’s current President was derided as Nelson Mandela was honoured

Graham Norton was issued with a warning from the BBC after he wore a red World AIDS Day charity ribbon on his chat show on 29 November.

Graham Norton blasted by BBC for wearing red World AIDS Day charity ribbon

According to BBC guidelines, staff are to stay 'independent and distanced from charities and their agendas'

Nelson Mandela dead: Giant laser image of Madiba projected onto Table Mountain, Cape Town

A giant laser image of Nelson Mandela has been projected onto Table Mountain in South Africa in an illuminated tribute to the late leader.

Tangled lives: Mandla Mandela speaking at a press conference on his his grandfather's health earlier in the year

The death of Nelson Mandela: The next generation - first the assault charge, then the state funeral

Mandela's grandson is destined to be in the news, starting this week

If all people lived in isolation for a year, would we wipe out all contagious diseases?’

Each person is teeming with bacteria, and we have a lot of viruses, too. A lot of the bacteria that live on and in our bodies can cause disease even if they aren't causing problems at the moment (for instance, E coli in the gut). So, no way. If each person lived in isolation for a year they'd still come out teeming with germs. But maybe it would theoretically wipe out some certain pathogen – I can't think of any, though. We actually need our bacteria, a lot of what goes on is a symbiotic relationship.

Nelson Mandela's successors Jacob Zuma (left) and Thabo Mbeki (right) have largely failed to follow his example

Nelson Mandela legacy: What now for the continent he bestrode like a colossus?

He was both an inspiration and a reproach to his fellow African heads of state. But will the great man’s example continue to resonate, now that he is gone?

Lawrence H. Summers said that governments and donors could create 'a grand convergence' and prevent 10 million avoidable deaths per year by 2035

Investment could end the 'health gap' between rich and poor in 20 years

The health gap between rich and poor countries could be wiped out in just 20 years’ time, leading economists and health experts have said, and can be achieved simply through greater investment in existing drugs, vaccines and treatments.

Don't Ever Wipe Tears without Gloves, BBC4 - TV Review

As regular BBC4 viewers are assured, Scandinavian public television is dour crime thriller after dour crime thriller occasionally leavened by a po-faced episode of Borgen. Or is it? This latest Swedish import suggests there's a much richer variety of drama on offer.

HIV positive predatory paedophile and his accomplice who led 'double lives' sentenced to life for abusing boys as young as thirteen

The pair used social networks, such as Bebo and Facebook, as well as specialist gay websites to groom boys

World AIDS Day: Forget politics, HIV could be the deadliest Arab up-rising yet

HIV is gaining ground in the Middle East and North Africa

Nursing students and medical staff hold candles and stand by a formation in the shape of a red ribbon, the universal symbol of awareness and support for those living with HIV, made with candles

World Aids Day 2013: The war on the epidemic is being won, but discrimination against sufferers is still rife

Deaths are down, however battling the stigma is the main obstacle to beating HIV once and for all

World Aids Day 2013: 'HIV is not in your mindset at 50-plus'

Freed from concerns over contraception and complacent over the risks of unprotected sex, a growing number of older people are falling victim to HIV – with new cases among heterosexual men and women doubling over the past decade.

An AIDS-free generation is within our reach

We are closer than ever before to ensuring that all children are born free from HIV and all those living with the disease can get the treatment they need

Britain's debt problems 'epidemic', warns think tank

One in four British households has a negative cash position

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Independent Travel
Pompeii, Capri & the Bay of Naples
Dubrovnik, the Dalmatian Coast & Montenegro
Burgundy, the River Rhone & Provence
Lisbon, Oporto and the Douro Valley
Lake Garda, Venice & Verona
Spain
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Isis hostage crisis: The prisoner swap has only one purpose for the militants - recognition its Islamic State exists and that foreign nations acknowledge its power

Isis hostage crisis

The prisoner swap has only one purpose for the militants - recognition its Islamic State exists and that foreign nations acknowledge its power, says Robert Fisk
Missing salvage expert who found $50m of sunken treasure before disappearing, tracked down at last

The runaway buccaneers and the ship full of gold

Salvage expert Tommy Thompson found sunken treasure worth millions. Then he vanished... until now
Homeless Veterans appeal: ‘If you’re hard on the world you are hard on yourself’

Homeless Veterans appeal: ‘If you’re hard on the world you are hard on yourself’

Maverick artist Grayson Perry backs our campaign
Assisted Dying Bill: I want to be able to decide about my own death - I want to have control of my life

Assisted Dying Bill: 'I want control of my life'

This week the Assisted Dying Bill is debated in the Lords. Virginia Ironside, who has already made plans for her own self-deliverance, argues that it's time we allowed people a humane, compassionate death
Move over, kale - cabbage is the new rising star

Cabbage is king again

Sophie Morris banishes thoughts of soggy school dinners and turns over a new leaf
11 best winter skin treats

Give your moisturiser a helping hand: 11 best winter skin treats

Get an extra boost of nourishment from one of these hard-working products
Paul Scholes column: The more Jose Mourinho attempts to influence match officials, the more they are likely to ignore him

Paul Scholes column

The more Jose Mourinho attempts to influence match officials, the more they are likely to ignore him
Frank Warren column: No cigar, but pots of money: here come the Cubans

Frank Warren's Ringside

No cigar, but pots of money: here come the Cubans
Isis hostage crisis: Militant group stands strong as its numerous enemies fail to find a common plan to defeat it

Isis stands strong as its numerous enemies fail to find a common plan to defeat it

The jihadis are being squeezed militarily and economically, but there is no sign of an implosion, says Patrick Cockburn
Virtual reality thrusts viewers into the frontline of global events - and puts film-goers at the heart of the action

Virtual reality: Seeing is believing

Virtual reality thrusts viewers into the frontline of global events - and puts film-goers at the heart of the action
Homeless Veterans appeal: MP says Coalition ‘not doing enough’

Homeless Veterans appeal

MP says Coalition ‘not doing enough’ to help
Larry David, Steve Coogan and other comedians share stories of depression in new documentary

Comedians share stories of depression

The director of the new documentary, Kevin Pollak, tells Jessica Barrett how he got them to talk
Has The Archers lost the plot with it's spicy storylines?

Has The Archers lost the plot?

A growing number of listeners are voicing their discontent over the rural soap's spicy storylines; so loudly that even the BBC's director-general seems worried, says Simon Kelner
English Heritage adds 14 post-war office buildings to its protected lists

14 office buildings added to protected lists

Christopher Beanland explores the underrated appeal of these palaces of pen-pushing
Human skull discovery in Israel proves humans lived side-by-side with Neanderthals

Human skull discovery in Israel proves humans lived side-by-side with Neanderthals

Scientists unearthed the cranial fragments from Manot Cave in West Galilee