Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

The Care Quality Commission (CQC) has announced a national review of dementia care

G8 Dementia Summit: PM pledges to double funding for research by 2025

While GlaxoSmithKline announces £200m of investment to set up a 'centre of excellence' that will turn breakthroughs in the lab into effective drugs

Jacob Zuma was greeted with hostility in Soweto

Nelson Mandela memorial: The booing of Jacob Zuma shows that divisions still remain

In front of leaders from around the world, South Africa’s current President was derided as Nelson Mandela was honoured

Graham Norton was issued with a warning from the BBC after he wore a red World AIDS Day charity ribbon on his chat show on 29 November.

Graham Norton blasted by BBC for wearing red World AIDS Day charity ribbon

According to BBC guidelines, staff are to stay 'independent and distanced from charities and their agendas'

Nelson Mandela dead: Giant laser image of Madiba projected onto Table Mountain, Cape Town

A giant laser image of Nelson Mandela has been projected onto Table Mountain in South Africa in an illuminated tribute to the late leader.

Tangled lives: Mandla Mandela speaking at a press conference on his his grandfather's health earlier in the year

The death of Nelson Mandela: The next generation - first the assault charge, then the state funeral

Mandela's grandson is destined to be in the news, starting this week

If all people lived in isolation for a year, would we wipe out all contagious diseases?’

Each person is teeming with bacteria, and we have a lot of viruses, too. A lot of the bacteria that live on and in our bodies can cause disease even if they aren't causing problems at the moment (for instance, E coli in the gut). So, no way. If each person lived in isolation for a year they'd still come out teeming with germs. But maybe it would theoretically wipe out some certain pathogen – I can't think of any, though. We actually need our bacteria, a lot of what goes on is a symbiotic relationship.

Nelson Mandela's successors Jacob Zuma (left) and Thabo Mbeki (right) have largely failed to follow his example

Nelson Mandela legacy: What now for the continent he bestrode like a colossus?

He was both an inspiration and a reproach to his fellow African heads of state. But will the great man’s example continue to resonate, now that he is gone?

Lawrence H. Summers said that governments and donors could create 'a grand convergence' and prevent 10 million avoidable deaths per year by 2035

Investment could end the 'health gap' between rich and poor in 20 years

The health gap between rich and poor countries could be wiped out in just 20 years’ time, leading economists and health experts have said, and can be achieved simply through greater investment in existing drugs, vaccines and treatments.

Don't Ever Wipe Tears without Gloves, BBC4 - TV Review

As regular BBC4 viewers are assured, Scandinavian public television is dour crime thriller after dour crime thriller occasionally leavened by a po-faced episode of Borgen. Or is it? This latest Swedish import suggests there's a much richer variety of drama on offer.

HIV positive predatory paedophile and his accomplice who led 'double lives' sentenced to life for abusing boys as young as thirteen

The pair used social networks, such as Bebo and Facebook, as well as specialist gay websites to groom boys

World AIDS Day: Forget politics, HIV could be the deadliest Arab up-rising yet

HIV is gaining ground in the Middle East and North Africa

Nursing students and medical staff hold candles and stand by a formation in the shape of a red ribbon, the universal symbol of awareness and support for those living with HIV, made with candles

World Aids Day 2013: The war on the epidemic is being won, but discrimination against sufferers is still rife

Deaths are down, however battling the stigma is the main obstacle to beating HIV once and for all

World Aids Day 2013: 'HIV is not in your mindset at 50-plus'

Freed from concerns over contraception and complacent over the risks of unprotected sex, a growing number of older people are falling victim to HIV – with new cases among heterosexual men and women doubling over the past decade.

An AIDS-free generation is within our reach

We are closer than ever before to ensuring that all children are born free from HIV and all those living with the disease can get the treatment they need

Britain's debt problems 'epidemic', warns think tank

One in four British households has a negative cash position

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Independent Travel
Pompeii, Capri & the Bay of Naples
Seven Cities of Italy
Burgundy, the River Rhone & Provence
Prague, Budapest and Vienna
Lake Garda
Minoan Crete and Santorini
Prices correct as of 15 May 2015
Isis profits from destruction of antiquities by selling relics to dealers - and then blowing up the buildings they come from to conceal the evidence of looting

How Isis profits from destruction of antiquities

Robert Fisk on the terrorist group's manipulation of the market to increase the price of artefacts
Labour leadership: Andy Burnham urges Jeremy Corbyn voters to think again in last-minute plea

'If we lose touch we’ll end up with two decades of the Tories'

In an exclusive interview, Andy Burnham urges Jeremy Corbyn voters to think again in last-minute plea
Tunisia fears its Arab Spring could be reversed as the new regime becomes as intolerant of dissent as its predecessor

The Arab Spring reversed

Tunisian protesters fear that a new law will whitewash corrupt businessmen and officials, but they are finding that the new regime is becoming as intolerant of dissent as its predecessor
King Arthur: Legendary figure was real and lived most of his life in Strathclyde, academic claims

Academic claims King Arthur was real - and reveals where he lived

Dr Andrew Breeze says the legendary figure did exist – but was a general, not a king
Who is Oliver Bonas and how has he captured middle-class hearts?

Who is Oliver Bonas?

It's the first high-street store to pay its staff the living wage, and it saw out the recession in style
Earth has 'lost more than half its trees' since humans first started cutting them down

Axe-wielding Man fells half the world’s trees – leaving us just 422 each

However, the number of trees may be eight times higher than previously thought
60 years of Scalextric: Model cars are now stuffed with as much tech as real ones

60 years of Scalextric

Model cars are now stuffed with as much tech as real ones
Theme parks continue to draw in thrill-seekers despite the risks - so why are we so addicted?

Why are we addicted to theme parks?

Now that Banksy has unveiled his own dystopian version, Christopher Beanland considers the ups and downs of our endless quest for amusement
Tourism in Iran: The country will soon be opening up again after years of isolation

Iran is opening up again to tourists

After years of isolation, Iran is reopening its embassies abroad. Soon, there'll be the chance for the adventurous to holiday there
10 best PS4 games

10 best PS4 games

Can’t wait for the new round of blockbusters due out this autumn? We played through last year’s offering
Transfer window: Ten things we learnt

Ten things we learnt from the transfer window

Record-breaking spending shows FFP restraint no longer applies
Migrant crisis: UN official Philippe Douste-Blazy reveals the harrowing sights he encountered among refugees arriving on Lampedusa

‘Can we really just turn away?’

Dead bodies, men drowning, women miscarrying – a senior UN figure on the horrors he has witnessed among migrants arriving on Lampedusa, and urges politicians not to underestimate our caring nature
Nine of Syria and Iraq's 10 world heritage sites are in danger as Isis ravages centuries of history

Nine of Syria and Iraq's 10 world heritage sites are in danger...

... and not just because of Isis vandalism
Girl on a Plane: An exclusive extract of the novelisation inspired by the 1970 Palestinian fighters hijack

Girl on a Plane

An exclusive extract of the novelisation inspired by the 1970 Palestinian fighters hijack
Why Frederick Forsyth's spying days could spell disaster for today's journalists

Why Frederick Forsyth's spying days could spell disaster for today's journalists

The author of 'The Day of the Jackal' has revealed he spied for MI6 while a foreign correspondent