Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

The Care Quality Commission (CQC) has announced a national review of dementia care

G8 Dementia Summit: PM pledges to double funding for research by 2025

While GlaxoSmithKline announces £200m of investment to set up a 'centre of excellence' that will turn breakthroughs in the lab into effective drugs

Jacob Zuma was greeted with hostility in Soweto

Nelson Mandela memorial: The booing of Jacob Zuma shows that divisions still remain

In front of leaders from around the world, South Africa’s current President was derided as Nelson Mandela was honoured

Graham Norton was issued with a warning from the BBC after he wore a red World AIDS Day charity ribbon on his chat show on 29 November.

Graham Norton blasted by BBC for wearing red World AIDS Day charity ribbon

According to BBC guidelines, staff are to stay 'independent and distanced from charities and their agendas'

Nelson Mandela dead: Giant laser image of Madiba projected onto Table Mountain, Cape Town

A giant laser image of Nelson Mandela has been projected onto Table Mountain in South Africa in an illuminated tribute to the late leader.

Tangled lives: Mandla Mandela speaking at a press conference on his his grandfather's health earlier in the year

The death of Nelson Mandela: The next generation - first the assault charge, then the state funeral

Mandela's grandson is destined to be in the news, starting this week

If all people lived in isolation for a year, would we wipe out all contagious diseases?’

Each person is teeming with bacteria, and we have a lot of viruses, too. A lot of the bacteria that live on and in our bodies can cause disease even if they aren't causing problems at the moment (for instance, E coli in the gut). So, no way. If each person lived in isolation for a year they'd still come out teeming with germs. But maybe it would theoretically wipe out some certain pathogen – I can't think of any, though. We actually need our bacteria, a lot of what goes on is a symbiotic relationship.

Nelson Mandela's successors Jacob Zuma (left) and Thabo Mbeki (right) have largely failed to follow his example

Nelson Mandela legacy: What now for the continent he bestrode like a colossus?

He was both an inspiration and a reproach to his fellow African heads of state. But will the great man’s example continue to resonate, now that he is gone?

Lawrence H. Summers said that governments and donors could create 'a grand convergence' and prevent 10 million avoidable deaths per year by 2035

Investment could end the 'health gap' between rich and poor in 20 years

The health gap between rich and poor countries could be wiped out in just 20 years’ time, leading economists and health experts have said, and can be achieved simply through greater investment in existing drugs, vaccines and treatments.

Don't Ever Wipe Tears without Gloves, BBC4 - TV Review

As regular BBC4 viewers are assured, Scandinavian public television is dour crime thriller after dour crime thriller occasionally leavened by a po-faced episode of Borgen. Or is it? This latest Swedish import suggests there's a much richer variety of drama on offer.

HIV positive predatory paedophile and his accomplice who led 'double lives' sentenced to life for abusing boys as young as thirteen

The pair used social networks, such as Bebo and Facebook, as well as specialist gay websites to groom boys

World AIDS Day: Forget politics, HIV could be the deadliest Arab up-rising yet

HIV is gaining ground in the Middle East and North Africa

Nursing students and medical staff hold candles and stand by a formation in the shape of a red ribbon, the universal symbol of awareness and support for those living with HIV, made with candles

World Aids Day 2013: The war on the epidemic is being won, but discrimination against sufferers is still rife

Deaths are down, however battling the stigma is the main obstacle to beating HIV once and for all

World Aids Day 2013: 'HIV is not in your mindset at 50-plus'

Freed from concerns over contraception and complacent over the risks of unprotected sex, a growing number of older people are falling victim to HIV – with new cases among heterosexual men and women doubling over the past decade.

An AIDS-free generation is within our reach

We are closer than ever before to ensuring that all children are born free from HIV and all those living with the disease can get the treatment they need

Britain's debt problems 'epidemic', warns think tank

One in four British households has a negative cash position

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Jeremy Clarkson has rejected criticisms of his language, according to BBC director of television Danny Cohen
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A polar bear’s diet is rich in seal blubber and half of its own body weight is composed of fat
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Judi Dench appeared at the Hay Festival to perform excerpts from Shakespearean plays
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Ronahi Serhat, a PKK fighter, in the Qandil Mountains in Iraqi Kurdistan
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Day In a Page

Burgundy, the River Rhone & Provence – MS Swiss Corona - seven nights from £999pp
Lake Maggiore, Orta and the Matterhorn – seven nights from £899pp
Sicily – seven nights from £939pp
Pompeii, Capri and the Bay of Naples - seven nights from £799pp
Istanbul Ephesus & Troy – six nights from £859pp
Mary Rose – two nights from £319pp
Air strikes? Talk of God? Obama is following the jihadists’ script

Air strikes? Talk of God? Obama is following the jihadists’ script

The President came the nearest he has come yet to rivalling George W Bush’s gormless reaction to 9/11 , says Robert Fisk
Ebola outbreak: Billy Graham’s son declares righteous war on the virus

Billy Graham’s son declares righteous war on Ebola

A Christian charity’s efforts to save missionaries trapped in Africa by the crisis have been justifiably praised. But doubts remain about its evangelical motives
Jeremy Clarkson 'does not see a problem' with his racist language on Top Gear, says BBC

Not even Jeremy Clarkson is bigger than the BBC, says TV boss

Corporation’s head of television confirms ‘Top Gear’ host was warned about racist language
Nick Clegg the movie: Channel 4 to air Coalition drama showing Lib Dem leader's rise

Nick Clegg the movie

Channel 4 to air Coalition drama showing Lib Dem leader's rise
Philip Larkin: Misogynist, racist, miserable? Or caring, playful man who lived for others?

Philip Larkin: What will survive of him?

Larkin's reputation has taken a knocking. But a new book by James Booth argues that the poet was affectionate, witty, entertaining and kind, as hitherto unseen letters, sketches and 'selfies' reveal
Madame Tussauds has shown off its Beyoncé waxwork in Regent's Park - but why is the tourist attraction still pulling in the crowds?

Waxing lyrical

Madame Tussauds has shown off its Beyoncé waxwork in Regent's Park - but why is the tourist attraction still pulling in the crowds?
Texas forensic astronomer finally pinpoints the exact birth of impressionism

Revealed (to the minute)

The precise time when impressionism was born
10 best men's skincare products

Face it: 10 best men's skincare products

Oscar Quine cleanses, tones and moisturises to find skin-savers blokes will be proud to display on the bathroom shelf
Middle East crisis: We know all too much about the cruelty of Isis – but all too little about who they are

We know all too much about the cruelty of Isis – but all too little about who they are

Now Obama has seen the next US reporter to be threatened with beheading, will he blink, asks Robert Fisk
Neanderthals lived alongside humans for centuries, latest study shows

Final resting place of our Neanderthal neighbours revealed

Bones dated to 40,000 years ago show species may have died out in Belgium species co-existed
Scottish independence: The new Scots who hold fate of the UK in their hands

The new Scots who hold fate of the UK in their hands

Scotland’s immigrants are as passionate about the future of their adopted nation as anyone else
Britain's ugliest buildings: Which monstrosities should be nominated for the Dead Prize?

Blight club: Britain's ugliest buildings

Following the architect Cameron Sinclair's introduction of the Dead Prize, an award for ugly buildings, John Rentoul reflects on some of the biggest blots on the UK landscape
eBay's enduring appeal: Online auction site is still the UK's most popular e-commerce retailer

eBay's enduring appeal

The online auction site is still the UK's most popular e-commerce site
Culture Minister Ed Vaizey: ‘lack of ethnic minority and black faces on TV is weird’

'Lack of ethnic minority and black faces on TV is weird'

Culture Minister Ed Vaizey calls for immediate action to address the problem
Artist Olafur Eliasson's latest large-scale works are inspired by the paintings of JMW Turner

Magic circles: Artist Olafur Eliasson

Eliasson's works will go alongside a new exhibition of JMW Turner at Tate Britain. He tells Jay Merrick why the paintings of his hero are ripe for reinvention