Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

“I’m better off dead” 11 year-old Nada al-Ahdal on child marriage

A video made by 11 year-old Yemeni girl Nada Al-Adhal speaking about child marriage has gone viral.

From Uganda to Britain: Life was much better before I started to think about the pain of hunger

Since arriving in Britain, one thing I have failed to wrap my head around is the fact that there is poverty, homelessness and hunger in the developed world, just like in Africa

The use of party drugs, usually found in nightclubs, to enjoy sex has caused concern

Party drugs linked to alarming rise in HIV amongst gay men

London sees 20 per cent rise in infections as charities call for better sexual health services

Singer Sir Elton John performing on stage during the Diamond Jubilee concert at Buckingham Palace last year

Page 3 Profile: Sir Elton John, musician

Ah Sir Elton, a national treasure.

Gay Marriage Bill: This has been a wonderful day. I only wish the 14-year-old me could have seen it

When the Queen signed the Marriage (Same Sex Couples) Bill into law today she’ll have had no idea what it will really mean for gay people. I do.

Nelson Mandela's granddaughter speaks of her hurt over the family's dispute

Ndileka Mandela speaks to the BBC of the pain the family have undergone since Mr Mandela was taken ill

Jimmy Savile with Margaret Thatcher

Margaret Thatcher made repeated attempts to get Jimmy Savile knighted – despite pleas from concerned aides

Former Prime Minister made four attempts to appoint disgraced presenter to knighthood before succeeding in 1990

Bone-marrow transplants leave men ‘HIV-free’

Two men infected with HIV for many years have been able to stop taking anti-viral drugs following bone-marrow transplants which left them without any detectable Aids virus in their bodies, scientists have announced.

A hearse is pictured at Mvezo resort after being accompanied by a police convoy to collect the remains of former South African President Nelson Mandela's children

Return to Qunu: Mandela family remains exhumed again

Battle over bodies of statesman’s children ends as they are taken back to ancestral village

Electron microscope image of the Aids virus

Two HIV-infected men treated with bone marrow transplants 'have no detectable Aids virus'

One patient has now been off anti-retroviral drug treatment for 15 weeks and the other for seven weeks

Mandla Mandela addressing the media last month

Judge orders Nelson Mandela's grandson Mandla to exhume bodies of anti-apartheid leader's children

A judge ordered Nelson Mandela's grandson to exhume the bodies of three of the anti-apartheid leader's children today and return them to their original graves, the latest twist in a dispute that has divided South Africa's most famous family.

Shrien Dewani is accused of killing his bride Anni on their honeymoon in South Africa
Barack Obama and Tanzania's President Jakaya Kikwete, left, at a welcoming ceremony in Dar Es Salaam

Barack Obama arrives to warm welcome in Tanzania - and a surprise meeting with George W Bush

Hundreds of young people line the streets wearing t-shirts and sarongs bearing images of the President, who says he wants to move relations with Africa from aid to trade

US President Barack Obama, right, and First Lady Michelle Obama, left, tour Robben Island

Barack Obama pledges energy cash to light up Africa’s darkness

US President promises funding to provide 'the energy to lift people out of poverty' by doubling Africans' access to electricity

The WHO says drug treatment for HIV should start earlier, before the immune system is damaged and causes sickness

WHO says drug treatment for HIV should begin earlier

An ambitious plan to roll out HIV treatment to millions more patients around the globe has divided scientists who question whether it is focused on benefiting individuals or halting the spread of the disease.

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Alexis Sanchez missed a penalty before scoring the opening goal with a header at the back post
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Independent Travel
Burgundy, the River Rhone & Provence – Five-star MS Swiss Corona 7 nights from £999pp
Lake Como St Moritz & the Bernina Express 7 nights from £809pp
Vietnam
Lake Maggiore, Orta & the Matterhorn 7 nights from £939pp
South Africa
Spain
Prices correct as of 19 December 2014
A Christmas without hope: Fears grow in Gaza that the conflict with Israel will soon reignite

Christmas without hope

Gaza fears grow that conflict with Israel will soon reignite
After 150 years, you can finally visit the grisliest museum in the country

The 'Black Museum'

After 150 years, you can finally visit Britain's grisliest museum
No ho-ho-hos with Nick Frost's badass Santa

No ho-ho-hos with Nick Frost's badass Santa

Doctor Who Christmas Special TV review
Chilly Christmas: Swimmers take festive dip for charity

Chilly Christmas

Swimmers dive into freezing British waters for charity
Veterans' hostel 'overwhelmed by kindness' for festive dinner

Homeless Veterans appeal

In 2010, Sgt Gary Jamieson stepped on an IED in Afghanistan and lost his legs and an arm. He reveals what, and who, helped him to make a remarkable recovery
Isis in Iraq: Yazidi girls killing themselves to escape rape and imprisonment by militants

'Jilan killed herself in the bathroom. She cut her wrists and hanged herself'

Yazidi girls killing themselves to escape rape and imprisonment
Ed Balls interview: 'If I think about the deficit when I'm playing the piano, it all goes wrong'

Ed Balls interview

'If I think about the deficit when I'm playing the piano, it all goes wrong'
He's behind you, dude!

US stars in UK panto

From David Hasselhoff to Jerry Hall
Grace Dent's Christmas Quiz: What are you – a festive curmudgeon or top of the tree?

Grace Dent's Christmas Quiz

What are you – a festive curmudgeon or top of the tree?
Nasa planning to build cloud cities in airships above Venus

Nasa planning to build cloud cities in airships above Venus

Planet’s surface is inhospitable to humans but 30 miles above it is almost perfect
Surrounded by high-rise flats is a little house filled with Lebanon’s history - clocks, rifles, frogmen’s uniforms and colonial helmets

Clocks, rifles, swords, frogmen’s uniforms

Surrounded by high-rise flats is a little house filled with Lebanon’s history
Return to Gaza: Four months on, the wounds left by Israel's bombardment have not yet healed

Four months after the bombardment, Gaza’s wounds are yet to heal

Kim Sengupta is reunited with a man whose plight mirrors the suffering of the Palestinian people
Gastric surgery: Is it really the answer to the UK's obesity epidemic?

Is gastric surgery really the answer to the UK's obesity epidemic?

Critics argue that it’s crazy to operate on healthy people just to stop them eating
Homeless Veterans appeal: Christmas charity auction Part 2 - now LIVE

Homeless Veterans appeal: Christmas charity auction

Bid on original art, or trips of a lifetime to Africa or the 'Corrie' set, and help Homeless Veterans
Pantomime rings the changes to welcome autistic theatre-goers

Autism-friendly theatre

Pantomime leads the pack in quest to welcome all