News An image of a mouse embryo with beating heart generated totally from STAP cells

Experts say the ground-breaking discovery could pave way for routine use of stem cells in medicine

All-in-one 'polypill' could save lives, says report

An all-in-one “polypill” with the potential to save many tens of thousands of lives each year in the UK could be available in less than two years.

Lord Browne: Three steps to restoring Britain to its global manufacturing strength

All too often we lag behind competitors in translating the fruits of scientific research into commercial success

Shire dives as copycat is backed by US watchdog

Shares in the British FTSE 100 pharmaceuticals giant Shire yesterday dived 11 per cent after regulators shocked the City by giving their backing to a generic rival of one of its best-selling drugs.

Makhdoom Shahabuddin: The accused candidate is a party stalwart seen as embodying continuity

Politics turns to farce in Pakistan as judge orders arrest of candidate who could replace ousted prime minister

Pakistan’s attempt to select a new prime minister veered towards farce today as a court issued an arrest warrant for the man chosen by President Asif Ali Zardari to be his next premier.

US drug store giant Walgreens in £10bn Boots takeover

The largest pharmacy chain in the United States swooped on high street chemist Boots today as part of a shock £10 billion takeover deal.

Leading article: Our Army must learn to adapt

When the Army announces the biggest structural overhaul in half a century, there is no way to avoid controversy. Even more so given that the radical reform programme – known as Army 2020 – includes cuts in capability to meet the demands of significantly reduced defence spending. As many as 11 infantry regiments could go, including such illustrious names as the Black Watch and the Queen's Dragoon Guards.

Marks & Spencer boss awarded £2.5m pay deal

The boss of Marks & Spencer Marc Bolland was awarded a £2.5 million pay deal despite the retailer recording its first fall in profits in three years.

People wait for prescriptions at a state health fund office in Athens

Pharmacy queues show price Greeks are paying for credit breakdown

There were long queues outside a state-funded pharmacy in Athens yesterday as people lined up to get life-saving drugs for seriously ill relatives.

Glaxo gets hostile in bid for HGS

Pharmaceutical giant in $2.6bn takeover move on long-time treatments partner
A new iPhone app, 'Zombies Run!', adapts from Google maps to simulate hordes of the undead, being a new aid to survive if a zombie plague occur

Trending: Cross the road, then turn left at rotting flesh...

The inevitable and potentially imminent Zombie Apocalypse continues to excite software programmers everywhere. Following the release of "Zombies, Run!", an app that helps iPhone users get fit by simulating hordes of the undead from which to flee (see Trending, 28 March), we now have Map of the Dead (, a new aid to post-apocalyptic survival from Jeff Merrick of the Doejo digital agency.

Dechra buys rival to expand in EU

Dechra Pharmaceuticals, which makes medicines for pets and livestock, yesterday spent €135m (£112m) buying a smaller Dutch rival that makes drugs for cattle, horses, dogs, pigs, cats and chickens.

James Moore: Drug makers in a fix as new treatments fall short

Outlook: Ouch. TC-5214 has tipped up. AstraZeneca is facing up to the failure of yet another drug from its already limited looking pipeline of new treatments.

iPads and iPods are the gadgets that help Bolton pupils do their homework and e-mail their teachers

The school where every teacher has an iPad... and every student has an iPod

Richard Garner visits the Bolton state comprehensive where pupils can email tutors for help – day or night

We will 'grow' all organs to order in future, says pioneering surgeon

Doctor who gave woman world's first lab-made body part predicts more breakthroughs to come

Spotlight On... Leif Johansson, chairman designate of AstraZeneca

I've not heard much about him before...

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Independent Travel
Burgundy, the River Rhone & Provence – Five-star MS Swiss Corona 7 nights from £999pp
Lake Como St Moritz & the Bernina Express 7 nights from £809pp
Lake Maggiore, Orta & the Matterhorn 7 nights from £939pp
South Africa
Prices correct as of 19 December 2014
Amir Khan: 'The Taliban can threaten me but I must speak out... innocent kids, killed over nothing. It’s sick in the mind'

Amir Khan attacks the Taliban

'They can threaten me but I must speak out... innocent kids, killed over nothing. It’s sick in the mind'
Homeless Veterans appeal: 'You look for someone who's an inspiration and try to be like them'

Homeless Veterans appeal

In 2010, Sgt Gary Jamieson stepped on an IED in Afghanistan and lost his legs and an arm. He reveals what, and who, helped him to make a remarkable recovery
Could cannabis oil reverse the effects of cancer?

Could cannabis oil reverse effects of cancer?

As a film following six patients receiving the controversial treatment is released, Kate Hilpern uncovers a very slippery issue
The Interview movie review: You can't see Seth Rogen and James Franco's Kim Jong Un assassination film, but you can read about it here

The Interview movie review

You can't see Seth Rogen and James Franco's Kim Jong Un assassination film, but you can read about it here
Serial mania has propelled podcasts into the cultural mainstream

How podcasts became mainstream

People have consumed gripping armchair investigation Serial with a relish typically reserved for box-set binges
Jesus Christ has become an unlikely pin-up for hipster marketing companies

Jesus Christ has become an unlikely pin-up

Kevin Lee Light, aka "Jesus", is the newest client of creative agency Mother while rival agency Anomaly has launched Sexy Jesus, depicting the Messiah in a series of Athena-style poses
Rosetta space mission voted most important scientific breakthrough of 2014

A memorable year for science – if not for mice

The most important scientific breakthroughs of 2014
Christmas cocktails to make you merry: From eggnog to Brown Betty and Rum Bumpo

Christmas cocktails to make you merry

Mulled wine is an essential seasonal treat. But now drinkers are rediscovering other traditional festive tipples. Angela Clutton raises a glass to Christmas cocktails
5 best activity trackers

Fitness technology: 5 best activity trackers

Up the ante in your regimen and change the habits of a lifetime with this wearable tech
Paul Scholes column: It's a little-known fact, but I have played one of the seven dwarves

Paul Scholes column

It's a little-known fact, but I have played one of the seven dwarves
Fifa's travelling circus once again steals limelight from real stars

Fifa's travelling circus once again steals limelight from real stars

Club World Cup kicked into the long grass by the continued farce surrounding Blatter, Garcia, Russia and Qatar
Frank Warren column: 2014 – boxing is back and winning new fans

Frank Warren: Boxing is back and winning new fans

2014 proves it's now one of sport's biggest hitters again
Jeb Bush vs Hillary Clinton: The power dynamics of the two first families

Jeb Bush vs Hillary Clinton

Karen Tumulty explores the power dynamics of the two first families
Stockholm is rivalling Silicon Valley with a hotbed of technology start-ups

Stockholm is rivalling Silicon Valley

The Swedish capital is home to two of the most popular video games in the world, as well as thousands of technology start-ups worth hundreds of millions of pounds – and it's all happened since 2009
Did Japanese workers really get their symbols mixed up and display Santa on a crucifix?

Crucified Santa: Urban myth refuses to die

The story goes that Japanese store workers created a life-size effigy of a smiling "Father Kurisumasu" attached to a facsimile of Our Lord's final instrument of torture