News An image of a mouse embryo with beating heart generated totally from STAP cells

Experts say the ground-breaking discovery could pave way for routine use of stem cells in medicine

Prisons chief Nick Hardwick warns over resources

Prisoners are spending too much time stuck in their cells watching daytime television because of a lack of resources, the Chief Inspector of Prisons has said.

Simon Timson is the new director of performance for UK Sport

Cricket guru Simon Timson given Rio role

Simon Timson, one of the men behind England's rise to No 1 in cricket's Test rankings, has been given the task of overseeing Britain's attempt to improve on their London medal haul at the Rio Olympics.

Employees of Sanofi protest against job cuts

Exclusive: MS drug 'rebranded' – at up to 20 times the price

Pharmaceutical giant withdraws existing treatment to boost profits

Federal and state health officials are scrambling to contact patients who might be affected by the widening outbreak

13,000 patients may have been exposed to fungus

As many as 13,000 patients across the US had steroid injections that may have been contaminated by a fungus linked to a rare form of meningitis that has killed eight people, federal officials said yesterday.

AstraZeneca new boss's debut buy

AstraZeneca's new boss yesterday agreed his first major deal at the pharmaceuticals giant, spending up to $272m (£169m) on the rights to an experimental kidney drug. This month, on his first day in the job, Pascal Soriot suspended Astra's share buybacks for the rest of the year.

Britain's Sir John Gurdon wins Nobel prize in medicine for his pioneering work in cloning and stem cells

The 79-year-old was the first person to clone an animal from a single cell

Medicine implicated in rare meningitis cases went to 23 US states

More than 17,000 vials of an injectable steroid that has been linked to 35 cases of meningitis, five of them fatal, were sent to doctors' offices and clinics in 23 states over the summer, health officials said yesterday.

18,000 websites selling illegal medicines closed down

More than 18,000 websites selling illegal medicines have been shut down during a global crackdown on illicit internet trade in pharmaceuticals.

Damned By Chuck Palahniuk

"Are you there, Satan? It's me, Madison" – so the preppy heroine of Palahniuk's novel kicks off each new chapter, cutely pardoying Judy Blume's Are You There, God? It's Me, Margaret.

Inside Obama's war on weed

Does anybody still think criminalising drugs works? Alas, most people do, including Barack Obama. He was a dope user in his younger days, and when asked if he inhaled (Bill Clinton having said he didn't), responded: "I inhaled frequently. That was kind of the point." In America today, seventeen states say cannabis can be distributed for medical purposes. The Daily Beast has a fine report on what that means in practice.

Market Report: Shire gets a boost from legal hopes

The wider market may have been feeling rather poorly yesterday, but Shire was one stock looking somewhat healthier. The drugs manufacturer found itself among the top blue-chip risers amid optimistic comments over its upcoming legal battles.

Leading article: Drugs companies, heal thyselves

Research suggesting that the vast majority of the new drugs launched by pharmaceutical companies are only tweaked versions of old ones, with little – if any – improvement in therapeutic effect, cannot but be alarming. The good news, however, is that there is a solution, or at least the start of one, if regulators are prepared to be brave.

AstraZeneca forced to swallow more dire sales

AstraZeneca, the struggling drug maker which is without a permanent boss after its chief executive quit under shareholder pressure, yesterday had another ailment to deal with as second-quarter sales fell by a fifth.

More trouble for leaderless AstraZeneca as sales dive

Pre-tax profit was down by 36 per cent at £3.8bn in the first half of 2012

GlaxoSmithKline return to sales growth is held back by austerity-led price pressure

Sharp declines in drug revenues in Europe and the US as austerity-struck governments demand price cuts saw Britain's biggest pharmaceuticals group, GlaxoSmithKline, yesterday warn of flat sales this year.

Career Services

Day In a Page

Independent Travel
Pompeii, Capri & the Bay of Naples
Dubrovnik, the Dalmatian Coast & Montenegro
Burgundy, the River Rhone & Provence
Lisbon, Oporto and the Douro Valley
Lake Garda, Venice & Verona
Spain
Prices correct as of 23 January 2015
Syria crisis: Celebrities call on David Cameron to take more refugees as one young mother tells of torture by Assad regime

Celebrities call on David Cameron to take more Syrian refugees

One young mother tells of torture by Assad regime
The enemy within: People who hear voices in their heads are being encouraged to talk back – with promising results

The enemy within

People who hear voices in their heads are being encouraged to talk back
'In Auschwitz you got used to anything'

'In Auschwitz you got used to anything'

Survivors of the Nazi concentration camp remember its horror, 70 years on
Autumn/winter menswear 2015: The uniforms that make up modern life come to the fore

Autumn/winter menswear 2015

The uniforms that make up modern life come to the fore
'I'm gay, and plan to fight military homophobia'

'I'm gay, and plan to fight military homophobia'

Army general planning to come out
Iraq invasion 2003: The bloody warnings six wise men gave to Tony Blair as he prepared to launch poorly planned campaign

What the six wise men told Tony Blair

Months before the invasion of Iraq in 2003, experts sought to warn the PM about his plans. Here, four of them recall that day
25 years of The Independent on Sunday: The stories, the writers and the changes over the last quarter of a century

25 years of The Independent on Sunday

The stories, the writers and the changes over the last quarter of a century
Homeless Veterans appeal: 'Really caring is a dangerous emotion in this kind of work'

Homeless Veterans appeal

As head of The Soldiers' Charity, Martin Rutledge has to temper compassion with realism. He tells Chris Green how his Army career prepared him
Wu-Tang Clan and The Sexual Objects offer fans a chance to own the only copies of their latest albums

Smash hit go under the hammer

It's nice to pick up a new record once in a while, but the purchasers of two latest releases can go a step further - by buying the only copy
Geeks who rocked the world: Documentary looks back at origins of the computer-games industry

The geeks who rocked the world

A new documentary looks back at origins of the computer-games industry
Belle & Sebastian interview: Stuart Murdoch reveals how the band is taking a new direction

Belle & Sebastian is taking a new direction

Twenty years ago, Belle & Sebastian was a fey indie band from Glasgow. It still is – except today, as prime mover Stuart Murdoch admits, it has a global cult following, from Hollywood to South Korea
America: Land of the free, home of the political dynasty

America: Land of the free, home of the political dynasty

These days in the US things are pretty much stuck where they are, both in politics and society at large, says Rupert Cornwell
A graphic history of US civil rights – in comic book form

A graphic history of US civil rights – in comic book form

A veteran of the Fifties campaigns is inspiring a new generation of activists
Winston Churchill: the enigma of a British hero

Winston Churchill: the enigma of a British hero

A C Benson called him 'a horrid little fellow', George Orwell would have shot him, but what a giant he seems now, says DJ Taylor
Growing mussels: Precious freshwater shellfish are thriving in a unique green project

Growing mussels

Precious freshwater shellfish are thriving in a unique green project