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Tyler Doohan went back inside the bedroom of a burning trailer to try and save his disabled grandfather

New hope in fight against 'Lorenzo's Oil' disease

A dramatic breakthrough in the possible treatment of childhood diseases of the nervous system – including the disorder featured in the film Lorenzo's Oil – was announced by scientists in America yesterday.

Hey nonny no, no, no: Goths and pagans are reinventing morris dancing

Why the newcomers are putting the fear of God into the traditionalists

Dickens family seek to overturn writer's dying wish for no memorials

In 1869, a year before Charles Dickens died, he wrote in his will that he wanted to be remembered for his work alone. No plaques, no statues, "no monument memorial or testimonial whatever" were to be allowed to commemorate the life of one of Britain's greatest authors.

Leading article: A tale of two arguments

When a biography of a writer appears, the cry often goes up that what counts is the art not the life. And if the writer is living, then very often he or she will have objected to being written about, or at the very least refused to co-operate with the project.

Design & Interiors: Stokesay Court

It wasn't only Keira Knightley who ravished the eye in 'Atonement'. The film's setting left us swooning too.

Clash of cultures: the screaming minarets of Oxford

A plan to call Muslims to prayer with a loudspeaker has divided opinion in Britain's oldest university town. By Andy McSmith

Dreda Say Mitchell: It's not only white people fleeing our city centres

It doesn't feature on Location, Location, Location but "race" is back in the news as a factor in where people choose to live. Trevor Phillips, who chairs the Equality and Human Rights Commission, has reiterated his concerns that Britain could become a segregated society. The Bishop of Rochester thinks some Muslim areas are becoming no-go areas for outsiders, while others are comparing some of England's northern towns to Belfast. But is it actually true?

Enterprise of Exiles and Gloucester promises an enthralling collision

If the Lord Mayor's Show in Cardiff turns out to be a forward-dominated affair - Munster do not possess a back division worthy of the name; Biarritz have an attacking unit boasting all the talents, but prefer not to use it - what comes after may prove the perfect antidote. Tomorrow's European Challenge Cup final between Gloucester and London Irish at the Twickenham Stoop features two sides at the forefront of what might be called English rugby's All Black movement, which embraces the theory that tries are better than penalties, that handling is better than kicking, that one crisp miss-pass in midfield is better than two months' worth of rolling mauls.

Nell Gwyn, by Charles Beauclerk

Reheated queen of tarts

School Standards: Bouncing back: from failing list to the `magnificent seven'

A "MAGNIFICENT seven" schools were hailed yesterday as the most improved in England after moving from Ofsted's failing list to be named among the country's most outstanding.

Discovery of secret stairs brings Brontë to life

The secret staircase which inspired one of fiction's great characters has been uncovered, hidden behind oak panels and just as it was portrayed by Charlotte Brontë.

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Kevin Spacey and artistic director Matthew Warchus at the Old Vic party to honour Spacey
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Revealed: Why Mohammed Emwazi chose the 'safe option' of fighting for Isis, rather than following his friends to al-Shabaab in Somalia

Why Mohammed Emwazi chose Isis

His friends were betrayed and killed by al-Shabaab
'The solution can never be to impassively watch on while desperate people drown'
An open letter to David Cameron: Building fortress Europe has had deadly results

Open letter to David Cameron

Building the walls of fortress Europe has had deadly results
Tory candidates' tweets not as 'spontaneous' as they seem - you don't say!

You don't say!

Tory candidates' election tweets not as 'spontaneous' as they appear
Mubi: Netflix for people who want to stop just watching trash

So what is Mubi?

Netflix for people who want to stop just watching trash all the time
The impossible job: how to follow Kevin Spacey?

The hardest job in theatre?

How to follow Kevin Spacey
Armenian genocide: To continue to deny the truth of this mass human cruelty is close to a criminal lie

Armenian genocide and the 'good Turks'

To continue to deny the truth of this mass human cruelty is close to a criminal lie
Lou Reed: The truth about the singer's upbringing beyond the biographers' and memoirists' myths

'Lou needed care, but what he got was ECT'

The truth about the singer's upbringing beyond
Migrant boat disaster: This human tragedy has been brewing for four years and EU states can't say they were not warned

This human tragedy has been brewing for years

EU states can't say they were not warned
Women's sportswear: From tackling a marathon to a jog in the park, the right kit can help

Women's sportswear

From tackling a marathon to a jog in the park, the right kit can help
Hillary Clinton's outfits will be as important as her policies in her presidential bid

Clinton's clothes

Like it or not, her outfits will be as important as her policies
NHS struggling to monitor the safety and efficacy of its services outsourced to private providers

Who's monitoring the outsourced NHS services?

A report finds that private firms are not being properly assessed for their quality of care
Zac Goldsmith: 'I'll trigger a by-election over Heathrow'

Zac Goldsmith: 'I'll trigger a by-election over Heathrow'

The Tory MP said he did not want to stand again unless his party's manifesto ruled out a third runway. But he's doing so. Watch this space
How do Greek voters feel about Syriza's backtracking on its anti-austerity pledge?

How do Greeks feel about Syriza?

Five voters from different backgrounds tell us what they expect from Syriza's charismatic leader Alexis Tsipras
From Iraq to Libya and Syria: The wars that come back to haunt us

The wars that come back to haunt us

David Cameron should not escape blame for his role in conflicts that are still raging, argues Patrick Cockburn
Sam Baker and Lauren Laverne: Too busy to surf? Head to The Pool

Too busy to surf? Head to The Pool

A new website is trying to declutter the internet to help busy women. Holly Williams meets the founders