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Tyler Doohan went back inside the bedroom of a burning trailer to try and save his disabled grandfather

New hope in fight against 'Lorenzo's Oil' disease

A dramatic breakthrough in the possible treatment of childhood diseases of the nervous system – including the disorder featured in the film Lorenzo's Oil – was announced by scientists in America yesterday.

Hey nonny no, no, no: Goths and pagans are reinventing morris dancing

Why the newcomers are putting the fear of God into the traditionalists

Leading article: A tale of two arguments

When a biography of a writer appears, the cry often goes up that what counts is the art not the life. And if the writer is living, then very often he or she will have objected to being written about, or at the very least refused to co-operate with the project.

Dickens family seek to overturn writer's dying wish for no memorials

In 1869, a year before Charles Dickens died, he wrote in his will that he wanted to be remembered for his work alone. No plaques, no statues, "no monument memorial or testimonial whatever" were to be allowed to commemorate the life of one of Britain's greatest authors.

Design & Interiors: Stokesay Court

It wasn't only Keira Knightley who ravished the eye in 'Atonement'. The film's setting left us swooning too.

Clash of cultures: the screaming minarets of Oxford

A plan to call Muslims to prayer with a loudspeaker has divided opinion in Britain's oldest university town. By Andy McSmith

Dreda Say Mitchell: It's not only white people fleeing our city centres

It doesn't feature on Location, Location, Location but "race" is back in the news as a factor in where people choose to live. Trevor Phillips, who chairs the Equality and Human Rights Commission, has reiterated his concerns that Britain could become a segregated society. The Bishop of Rochester thinks some Muslim areas are becoming no-go areas for outsiders, while others are comparing some of England's northern towns to Belfast. But is it actually true?

Enterprise of Exiles and Gloucester promises an enthralling collision

If the Lord Mayor's Show in Cardiff turns out to be a forward-dominated affair - Munster do not possess a back division worthy of the name; Biarritz have an attacking unit boasting all the talents, but prefer not to use it - what comes after may prove the perfect antidote. Tomorrow's European Challenge Cup final between Gloucester and London Irish at the Twickenham Stoop features two sides at the forefront of what might be called English rugby's All Black movement, which embraces the theory that tries are better than penalties, that handling is better than kicking, that one crisp miss-pass in midfield is better than two months' worth of rolling mauls.

Nell Gwyn, by Charles Beauclerk

Reheated queen of tarts

School Standards: Bouncing back: from failing list to the `magnificent seven'

A "MAGNIFICENT seven" schools were hailed yesterday as the most improved in England after moving from Ofsted's failing list to be named among the country's most outstanding.

Discovery of secret stairs brings Brontë to life

The secret staircase which inspired one of fiction's great characters has been uncovered, hidden behind oak panels and just as it was portrayed by Charlotte Brontë.

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Isis profits from destruction of antiquities by selling relics to dealers - and then blowing up the buildings they come from to conceal the evidence of looting

How Isis profits from destruction of antiquities

Robert Fisk on the terrorist group's manipulation of the market to increase the price of artefacts
Labour leadership: Andy Burnham urges Jeremy Corbyn voters to think again in last-minute plea

'If we lose touch we’ll end up with two decades of the Tories'

In an exclusive interview, Andy Burnham urges Jeremy Corbyn voters to think again in last-minute plea
Tunisia fears its Arab Spring could be reversed as the new regime becomes as intolerant of dissent as its predecessor

The Arab Spring reversed

Tunisian protesters fear that a new law will whitewash corrupt businessmen and officials, but they are finding that the new regime is becoming as intolerant of dissent as its predecessor
King Arthur: Legendary figure was real and lived most of his life in Strathclyde, academic claims

Academic claims King Arthur was real - and reveals where he lived

Dr Andrew Breeze says the legendary figure did exist – but was a general, not a king
Who is Oliver Bonas and how has he captured middle-class hearts?

Who is Oliver Bonas?

It's the first high-street store to pay its staff the living wage, and it saw out the recession in style
Earth has 'lost more than half its trees' since humans first started cutting them down

Axe-wielding Man fells half the world’s trees – leaving us just 422 each

However, the number of trees may be eight times higher than previously thought
60 years of Scalextric: Model cars are now stuffed with as much tech as real ones

60 years of Scalextric

Model cars are now stuffed with as much tech as real ones
Theme parks continue to draw in thrill-seekers despite the risks - so why are we so addicted?

Why are we addicted to theme parks?

Now that Banksy has unveiled his own dystopian version, Christopher Beanland considers the ups and downs of our endless quest for amusement
Tourism in Iran: The country will soon be opening up again after years of isolation

Iran is opening up again to tourists

After years of isolation, Iran is reopening its embassies abroad. Soon, there'll be the chance for the adventurous to holiday there
10 best PS4 games

10 best PS4 games

Can’t wait for the new round of blockbusters due out this autumn? We played through last year’s offering
Transfer window: Ten things we learnt

Ten things we learnt from the transfer window

Record-breaking spending shows FFP restraint no longer applies
Migrant crisis: UN official Philippe Douste-Blazy reveals the harrowing sights he encountered among refugees arriving on Lampedusa

‘Can we really just turn away?’

Dead bodies, men drowning, women miscarrying – a senior UN figure on the horrors he has witnessed among migrants arriving on Lampedusa, and urges politicians not to underestimate our caring nature
Nine of Syria and Iraq's 10 world heritage sites are in danger as Isis ravages centuries of history

Nine of Syria and Iraq's 10 world heritage sites are in danger...

... and not just because of Isis vandalism
Girl on a Plane: An exclusive extract of the novelisation inspired by the 1970 Palestinian fighters hijack

Girl on a Plane

An exclusive extract of the novelisation inspired by the 1970 Palestinian fighters hijack
Why Frederick Forsyth's spying days could spell disaster for today's journalists

Why Frederick Forsyth's spying days could spell disaster for today's journalists

The author of 'The Day of the Jackal' has revealed he spied for MI6 while a foreign correspondent