Sport Peyton Manning broke Tom Brady's record for touchdown passes in a season

Devastated by injury and dumped by his beloved team, one of the NFL’s all-time great quarterbacks is back in business and breaking records

Scientists are closer to building a biological computer after they managed to make a transistor from DNA and RNA

Biological computer that 'lives' inside the body comes one step closer as scientists make transistor out of DNA and RNA

Finding could lead to new biodegradable devices based on living cells that are capable of detecting changes in the environment

Cosmic! Scientists clear up one of large unsolved puzzles about our Universe

Scientists have solved the mystery of cosmic rays, a stream of highly-energetic sub-atomic particles that pervades the Universe and is responsible for much of the extra radiation dose received by airline passengers.

Judging by the complaints, sanctions are inflicting pain

I co-ordinated the UN Panel of Experts charged with improving implementation of the Security Council sanctions for a year and am often asked how effective they are. Clearly they have not halted the North Korean nuclear programme but they have almost certainly slowed it down and, judging by the constant shrill complaints, they are certainly inflicting pain. Perhaps not least, the North Koreans regard them as a humiliation – they bitterly resent being treated as a pariah and crave respectability.

Toe pokes: Vibram FiveFingers shoes

To boldly toe: ToPo Athletic split foot trainers are more science than gimmick

The man behind the world's weirdest running shoes is back with a new hi-tech trainer. Simon Usborne laces up

Missing person: The Manti Te’o headlines went from hero to hoax after his heart-warming tale turned into a whodunit

American Football: Solved - the case of the girlfriend who never was

As mysteries go, the one involving the Notre Dame linebacker Manti Te'o and his "dead" girlfriend takes some beating. Yesterday, like the next chapter in a detective novel, it unveiled another twist which will only serve to ratchet up the interest in this bizarre story.

Commitment to social justice: Swartz in December 2012

Aaron Swartz: Campaigner for internet freedom

Aaron Swartz was a campaigner for internet freedom and a software developer who made an enormous impact during his 26 short years on the planet. His campaigning work and direct action for freedom of information had led him into frequent conflict with the authorities, with the result that, at the time of his death, he faced 13 felony charges for which he was due to stand trial within the coming months.

David Cameron’s official 'blue sky' thinker Steve Hilton

Cameron’s Mr Blue Sky: how we found out our own policies from the papers

On sabbatical in California, Steve Hilton reveals ‘horror’ at how No 10 really works

This week's wackiest stories from the web: Stupid evolution and the first burger in space

If you have sex in public, but no one is watching, is it still obscene? Plus bones of ancient giant discovered and that regrettable Romney face tattoo

Brain imaging, such as this pictured at the Leibniz Institute for Neurobiology, is proving vital for understanding how the mind works

Identifying the brain's own facial recognition system

The ability to recognize faces is so important in humans that the brain appears to have an area solely devoted to the task: the fusiform gyrus.

The iPhone: Can't live without it

One teenager faces the ultimate challenge: A week without her iPhone

I just spent a week without one of the most important things in my life. It's something that I never go anywhere without, that I talk to when I'm lonely, that I stare at for hours upon end, day after day. It's there for me when my friends are not. It never argues with me or makes me feel bad about myself. I love it dearly and I can make it tell me that it loves me, too: My iPhone.

Awe therapy could 'improve our mental health and make us nicer'

A jaw-dropping moment really can make time appear to stand still - or at least slow down, new research suggests.

Stephen Hawking's thoughts... unredacted and unedited

A man like Stephen Hawking, renowned for his complex thinking, might be happy to have scientists read his brainwaves. The Cambridge professor, who suffers from motor neurone disease and is losing his ability to communicate via computer, is working with scientists hoping to read his brain.

Tests on fake retina 'encouraging'

Tests on a device that could restore sight to patients suffering from a common cause of blindness have produced "encouraging" results.

Andrew Luck is one of the names to watch at the NFL draft

American Football: Do believe the hype! NFL draft is the craziest show in town

It is fantasy football come true. Thirty-two teams picking future gridiron superstars live on prime-time television. What's not to like?

Cameron is a touch-screen Tory and totally techno -no surprise he has his own app

What's on Dave's dashboard?

David Cameron now has a special app to run the country. But what else is on his iPad? John Rentoul sneaks an iPeek

News
newsAnother week, another dress controversy on the internet
Life and Style
Scientist have developed a test which predicts whether you'll live for another ten years
health
Sport
Dave Mackay lifts the FA Cup in 1967 having skippered Spurs to victory
football
Life and Style
Marie had fake ID, in the name of Johanna Koch, after she evaded capture by the Nazis in wartime Berlin
historyOne woman's secret life as a Jew in wartime Berlin
News
news... and what your reaction to the creatures above says about you
News
Jihadi John
newsMonikers like 'Jihadi John' make the grim sound glamorous
Arts and Entertainment
As depicted in Disney's Robin Hood, King John was cowardly, cruel, avaricious and incompetent
film
Life and Style
Travis Kalanick, the co-founder of Uber, is now worth $5.3bn
tech
News
Homer’s equation, in an episode in 1998, comes close to the truth, as revealed 14 years later
science
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Day In a Page

Independent Travel
Pompeii, Capri & the Bay of Naples
Seven Cities of Italy
Burgundy, the River Rhone & Provence
Prague, Budapest and Vienna
Lake Garda
3.	Provence 6 nights B&B by train from £599pp
Prices correct as of 20 February 2015
Syrian conflict is the world's first 'climate change war', say scientists, but it won't be the last one

Climate change key in Syrian conflict

And it will trigger more war in future
How I outwitted the Gestapo

How I outwitted the Gestapo

My life as a Jew in wartime Berlin
The nation's favourite animal revealed

The nation's favourite animal revealed

Women like cuddly creatures whilst men like creepy-crawlies
Is this the way to get young people to vote?

Getting young people to vote

From #VOTESELFISH to Bite the Ballot
Poldark star Heida Reed: 'I don't think a single bodice gets ripped'

Poldark star Heida Reed

'I don't think a single bodice gets ripped'
The difference between America and Israel? There isn’t one

The difference between America and Israel? There isn’t one

Netanyahu knows he can get away with anything in America, says Robert Fisk
Families clubbing together to build their own affordable accommodation

Do It Yourself approach to securing a new house

Community land trusts marking a new trend for taking the initiative away from developers
Head of WWF UK: We didn’t send Cameron to the Arctic to see green ideas freeze

David Nussbaum: We didn’t send Cameron to the Arctic to see green ideas freeze

The head of WWF UK remains sanguine despite the Government’s failure to live up to its pledges on the environment
Author Kazuo Ishiguro on being inspired by shoot-outs and samurai

Author Kazuo Ishiguro on being inspired by shoot-outs and samurai

Set in a mythologised 5th-century Britain, ‘The Buried Giant’ is a strange beast
With money, corruption and drugs, this monk fears Buddhism in Thailand is a ‘poisoned fruit’

Money, corruption and drugs

The monk who fears Buddhism in Thailand is a ‘poisoned fruit’
America's first slavery museum established at Django Unchained plantation - 150 years after slavery outlawed

150 years after it was outlawed...

... America's first slavery museum is established in Louisiana
Kelly Clarkson: How I snubbed Simon Cowell and become a Grammy-winning superstar

Kelly Clarkson: How I snubbed Simon Cowell and become a Grammy-winning superstar

The first 'American Idol' winner on how she manages to remain her own woman – Jane Austen fascination and all
Tony Oursler on exploring our uneasy relationship with technology with his new show

You won't believe your eyes

Tony Oursler's new show explores our uneasy relationship with technology. He's one of a growing number of artists with that preoccupation
Ian Herbert: Peter Moores must go. He should never have been brought back to fail again

Moores must go. He should never have been brought back to fail again

The England coach leaves players to find solutions - which makes you wonder where he adds value, says Ian Herbert
War with Isis: Fears that the looming battle for Mosul will unleash 'a million refugees'

The battle for Mosul will unleash 'a million refugees'

Aid agencies prepare for vast exodus following planned Iraqi offensive against the Isis-held city, reports Patrick Cockburn