Sport Peyton Manning broke Tom Brady's record for touchdown passes in a season

Devastated by injury and dumped by his beloved team, one of the NFL’s all-time great quarterbacks is back in business and breaking records

Scientists are closer to building a biological computer after they managed to make a transistor from DNA and RNA

Biological computer that 'lives' inside the body comes one step closer as scientists make transistor out of DNA and RNA

Finding could lead to new biodegradable devices based on living cells that are capable of detecting changes in the environment

Cosmic! Scientists clear up one of large unsolved puzzles about our Universe

Scientists have solved the mystery of cosmic rays, a stream of highly-energetic sub-atomic particles that pervades the Universe and is responsible for much of the extra radiation dose received by airline passengers.

Judging by the complaints, sanctions are inflicting pain

I co-ordinated the UN Panel of Experts charged with improving implementation of the Security Council sanctions for a year and am often asked how effective they are. Clearly they have not halted the North Korean nuclear programme but they have almost certainly slowed it down and, judging by the constant shrill complaints, they are certainly inflicting pain. Perhaps not least, the North Koreans regard them as a humiliation – they bitterly resent being treated as a pariah and crave respectability.

Toe pokes: Vibram FiveFingers shoes

To boldly toe: ToPo Athletic split foot trainers are more science than gimmick

The man behind the world's weirdest running shoes is back with a new hi-tech trainer. Simon Usborne laces up

Missing person: The Manti Te’o headlines went from hero to hoax after his heart-warming tale turned into a whodunit

American Football: Solved - the case of the girlfriend who never was

As mysteries go, the one involving the Notre Dame linebacker Manti Te'o and his "dead" girlfriend takes some beating. Yesterday, like the next chapter in a detective novel, it unveiled another twist which will only serve to ratchet up the interest in this bizarre story.

Commitment to social justice: Swartz in December 2012

Aaron Swartz: Campaigner for internet freedom

Aaron Swartz was a campaigner for internet freedom and a software developer who made an enormous impact during his 26 short years on the planet. His campaigning work and direct action for freedom of information had led him into frequent conflict with the authorities, with the result that, at the time of his death, he faced 13 felony charges for which he was due to stand trial within the coming months.

David Cameron’s official 'blue sky' thinker Steve Hilton

Cameron’s Mr Blue Sky: how we found out our own policies from the papers

On sabbatical in California, Steve Hilton reveals ‘horror’ at how No 10 really works

This week's wackiest stories from the web: Stupid evolution and the first burger in space

If you have sex in public, but no one is watching, is it still obscene? Plus bones of ancient giant discovered and that regrettable Romney face tattoo

Brain imaging, such as this pictured at the Leibniz Institute for Neurobiology, is proving vital for understanding how the mind works

Identifying the brain's own facial recognition system

The ability to recognize faces is so important in humans that the brain appears to have an area solely devoted to the task: the fusiform gyrus.

The iPhone: Can't live without it

One teenager faces the ultimate challenge: A week without her iPhone

I just spent a week without one of the most important things in my life. It's something that I never go anywhere without, that I talk to when I'm lonely, that I stare at for hours upon end, day after day. It's there for me when my friends are not. It never argues with me or makes me feel bad about myself. I love it dearly and I can make it tell me that it loves me, too: My iPhone.

Awe therapy could 'improve our mental health and make us nicer'

A jaw-dropping moment really can make time appear to stand still - or at least slow down, new research suggests.

Stephen Hawking's thoughts... unredacted and unedited

A man like Stephen Hawking, renowned for his complex thinking, might be happy to have scientists read his brainwaves. The Cambridge professor, who suffers from motor neurone disease and is losing his ability to communicate via computer, is working with scientists hoping to read his brain.

Tests on fake retina 'encouraging'

Tests on a device that could restore sight to patients suffering from a common cause of blindness have produced "encouraging" results.

Andrew Luck is one of the names to watch at the NFL draft

American Football: Do believe the hype! NFL draft is the craziest show in town

It is fantasy football come true. Thirty-two teams picking future gridiron superstars live on prime-time television. What's not to like?

Cameron is a touch-screen Tory and totally techno -no surprise he has his own app

What's on Dave's dashboard?

David Cameron now has a special app to run the country. But what else is on his iPad? John Rentoul sneaks an iPeek

News
Bryan had a bracelet given to him by his late father stolen during the raid
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Sport
Tour de France competitor Bartosz Huzarski’s legs have highlighted the gruelling nature of the race, after he posted a picture on Facebook showing extremely prominent veins stretching from his feet and all the way up his legs
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A rub on the tummy sprang Casey back to life
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News
Susan Sarandon described David Bowie as
peopleSusan Sarandon reveals more on her David Bowie romance
Sport
Lewis Hamilton walks back to the pit lane with his Mercedes burning in the background
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Arts and Entertainment
The new characters were announced yesterday at San Diego Comic Con
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Arsenal supporters gather for a recent ‘fan party’ in New Jersey
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No Devotion's Geoff Rickly and Stuart Richardson
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sportDidier Drogba returns to Chelsea on one-year deal
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Day In a Page

Burgundy, the River Rhone & Provence – MS Swiss Corona - seven nights from £999pp
Lake Maggiore, Orta and the Matterhorn – seven nights from £899pp
Sicily – seven nights from £939pp
Pompeii, Capri and the Bay of Naples - seven nights from £799pp
Istanbul Ephesus & Troy – six nights from £859pp
Mary Rose – two nights from £319pp
Evan Davis: The BBC’s wolf in sheep’s clothing to take over at Newsnight

The BBC’s wolf in sheep’s clothing

What will Evan Davis be like on Newsnight?
Finding the names for America’s shame: What happens to the immigrants crossing the US-Mexico border without documents who never make it past the Arizona desert?

Finding the names for America’s shame

The immigrants crossing the US-Mexico border without documents who never make it past the Arizona desert
Inside a church for Born Again Christians: Speaking to God in a Manchester multiplex

Inside a church for Born Again Christians

As Britain's Anglican church struggles to establish its modern identity, one branch of Christianity is booming
Rihanna, Kim Kardashian and me: How Olivier Rousteing is revitalising the house of Balmain

Olivier Rousteing is revitalising the house of Balmain

Parisian couturier Pierre Balmain made his name dressing the mid-century jet set. Today, Olivier Rousteing – heir to the house Pierre built – is celebrating their 21st-century equivalents. The result? Nothing short of Balmania
Cancer, cardiac arrest, HIV and homelessness - and he's only 39

Incredible survival story of David Tovey

Tovey went from cooking for the Queen to rifling through bins for his supper. His is a startling story of endurance against the odds – and of a social safety net failing at every turn
Backhanders, bribery and abuses of power have soared in China as economy surges

Bribery and abuses of power soar in China

The bribery is fuelled by the surge in China's economy but the rules of corruption are subtle and unspoken, finds Evan Osnos, as he learns the dark arts from a master
Commonwealth Games 2014: Highland terriers stole the show at the opening ceremony

Highland terriers steal the show at opening ceremony

Gillian Orr explores why a dog loved by film stars and presidents is finally having its day
German art world rocked as artists use renowned fat sculpture to distil schnapps

Brewing the fat from artwork angers widow of sculptor

Part of Joseph Beuys' 1982 sculpture 'Fettecke' used to distil schnapps
BBC's The Secret History of Our Streets reveals a fascinating window into Britain's past

BBC takes viewers back down memory lane

The Secret History of Our Streets, which returns with three films looking at Scottish streets, is the inverse of Benefits Street - delivering warmth instead of cynicism
Joe, film review: Nicolas Cage delivers an astonishing performance in low budget drama

Nicolas Cage shines in low-budget drama Joe

Cage plays an ex-con in David Gordon Green's independent drama, which has been adapted from a novel by Larry Brown
How to make your own gourmet ice lollies, granitas, slushy cocktails and frozen yoghurt

Make your own ice lollies and frozen yoghurt

Think outside the cool box for this summer's tempting frozen treats
Ford Fiesta is UK's most popular car of all-time, with sales topping 4.1 million since 1976

Fiesta is UK's most popular car of all-time

Sales have topped 4.1 million since 1976. To celebrate this milestone, four Independent writers recall their Fiestas with pride
10 best reed diffusers

Heaven scent: 10 best reed diffusers

Keep your rooms smelling summery and fresh with one of these subtle but distinctive home fragrances that’ll last you months
Commonwealth Games 2014: Female boxers set to compete for first time

Female boxers set to compete at Commonwealth Games for first time

There’s no favourites and with no headguards anything could happen
Five things we’ve learned so far about Manchester United under Louis van Gaal

Five things we’ve learned so far about United under Van Gaal

It’s impossible to avoid the impression that the Dutch manager is playing to the gallery a little