Sport Peyton Manning broke Tom Brady's record for touchdown passes in a season

Devastated by injury and dumped by his beloved team, one of the NFL’s all-time great quarterbacks is back in business and breaking records

The Prime Minister's most influential adviser, Steve Hilton (pictured), has announced his departure from Downing Street

Steve Hilton's next Big Idea: Swap Downing Street for time out in California

He is credited as the architect of the Big Society and once suggested the abolition of paid maternity leave. Now Steve Hilton, David Cameron's most influential adviser, has pulled off one last surprise: unexpectedly announcing his departure from Downing Street for an unpaid academic job in California.

Conservative Party strategist Steve Hilton arrives in Downing Street on his bike earlier this month

Strategy guru Steve Hilton to take sabbatical

David Cameron's strategy guru Steve Hilton is quitting Downing Street for a year to take an academic position in the United States, Number 10 said.

A dead whitetip reef shark caught accidentally in a fishing net

Mobile marine reserves may end slaughter of endangered sea life

The indiscriminate slaughter of vast numbers of turtles, sharks, albatrosses and other endangered marine animals that get unintentionally caught by fishermen as “by-catch” could be prevented by a radical proposal of mobile marine reserves, scientists said yesterday.

Joy for San Francisco's Alex Smith as he scores a fourth-quarter touchdown against New Orleans Saints

American Football: Alex Smith - 'The Comeback Kid' goes from villain to hero in San Francisco

Much-maligned quarterback can guide the 49ers into an unlikely Super Bowl

Peter York: The secret and changing life of the private members' club

A chap banned for wearing a tie? Joanna Lumley at the Garrick? What <u>is</u> going on

Undisturbed night's sleep needed for good memory

A continuous night's uninterrupted sleep may be the essential requirement for a good memory, according to a study carried out on laboratory mice. The animals failed to remember things after being repeatedly disturbed while they dozed. The research is more subtle than it first appears because the researchers did not just investigate disturbed sleep, which can cause memory loss through stress, but also the length of time the mice engaged in deep sleep, when memories are believed to be consolidated by the resting brain.

Hope for millions of Alzheimer's sufferers as scientists make brain cells from human skin

Skin cells from a 30-year-old woman have been turned directly into mature nerve cells similar to those found in the brain using a procedure that promises to revolutionise the emerging field of regenerative medicine.

The <i>IoS</i> Happy List quiz 2011

Happiness is... puzzling over some daft questions in your favourite newspaper (answers at bottom of page)

Genetic breakthrough may pave way to new heart and stroke tests

Scientists have found the largest number of genes associated with an increased risk of developing heart disease in a study that helps to pave the way towards the day when doctors may be able to offer genetic tests that can identify people most at risk of heart attacks and strokes.

The Language Wars: a history of proper English, By Henry Hitchings

Wordsmith who's on the winning side

Larry Page: A very private poster boy

He will never make a showman. But as Google's co-founder steps up to be its CEO, can he display the business nous to match his genius as an inventor?

Employers discriminate against Muslims, study finds

Muslims face "massive discrimination" when applying for jobs, according to the first scientifically validated study of anti-Muslim bias among employers in France.

I'm no friend of Facebook film, says Zuckerberg

It's the movie everyone has been talking about, with the word Oscar regularly tripping from the lips of critics. But one voice has been notably absent from the discussion of The Social Network until now.

Consuming Issues: Hey big spender, it's all down to your genes

If you love chocolate, like me, you may be able to blame something other than considerable greed if you no longer fit into your jeans: your genes. Research is shedding light on the reasons we sometimes like things, or engage in risky behaviour.

New technique promises to take the lottery out of IVF

Thousands of infertile couples who repeatedly undergo IVF treatment in the hope of having a baby could soon benefit from a scientific breakthrough that promises a radical increase in the chances of a successful pregnancy.

Sport
The Pipes and Drums of The Scottish Regiments perform during the Opening Ceremony for the Glasgow 2014 Commonwealth Games at Celtic Park on July 23, 2014 in Glasgow, Scotland.
Commonwealth gamesThe actor encouraged the one billion viewers of the event to donate to the children's charity
Sport
Members of the Scotland deleagtion walk past during the opening ceremony of the 2014 Commonwealth Games at Celtic Park in Glasgow on July 23, 2014.
Voices
voicesGood for Lana Del Rey for helping kill that myth, writes Grace Dent
Sport
Shinji Kagawa and Reece James celebrate after the latter scores in Manchester United's 7-0 victory over LA Galaxy
football
Arts and Entertainment
The Tour de France peloton rides over a bridge on the Grinton Moor, Yorkshire, earlier this month
film
Life and Style
fashion Designs are part of feminist art project by a British student
News
Very tasty: Vladimir Putin dining alone, perhaps sensibly
news
Life and Style
Listen here: Apple EarPods offer an alternative
techAre custom, 3D printed earbuds the solution?
Arts and Entertainment
Top guns: Cole advised the makers of Second World War film Fury, starring Brad Pitt
filmLt-Col Steven Cole is the man Hollywood calls when it wants to borrow a tank or check a uniform
News
The University of California study monitored the reaction of 36 dogs
sciencePets' range of emotions revealed
Career Services

Day In a Page

Burgundy, the River Rhone & Provence – MS Swiss Corona - seven nights from £999pp
Lake Maggiore, Orta and the Matterhorn – seven nights from £899pp
Sicily – seven nights from £939pp
Pompeii, Capri and the Bay of Naples - seven nights from £799pp
Istanbul Ephesus & Troy – six nights from £859pp
Mary Rose – two nights from £319pp
Screwing your way to the top? Good for Lana Del Rey for helping kill that myth

Screwing your way to the top?

Good for Lana Del Rey for helping kill that myth, says Grace Dent
Will the young Britons fighting in Syria be allowed to return home and resume their lives?

Will Britons fighting in Syria be able to resume their lives?

Tony Blair's Terrorism Act 2006 has made it an offence to take part in military action abroad with a "political, ideological, religious or racial motive"
Beyoncé poses as Rosie the Riveter, the wartime poster girl who became a feminist pin-up

Beyoncé poses as Rosie the Riveter

The wartime poster girl became the ultimate American symbol of female empowerment
The quest to find the perfect pair of earphones: Are custom, 3D printed earbuds the solution?

The quest to find the perfect pair of earphones

Earphones don't fit properly, offer mediocre audio quality and can even be painful. So the quest to design the perfect pair is music to Seth Stevenson's ears
US Army's shooting star: Lt-Col Steven Cole is the man Hollywood calls when it wants to borrow a tank or check a military uniform

Meet the US Army's shooting star

Lt-Col Steven Cole is the man Hollywood calls when it wants to borrow a tank or check a military uniform
Climate change threatens to make the antarctic fur seal extinct

Take a good look while you can

How climate change could wipe out this seal
Should emergency hospital weddings be made easier for the terminally ill?

Farewell, my lovely

Should emergency hospital weddings be made easier?
Man Booker Prize 2014 longlist: Crowdfunded novel nominated for first time

Crowdfunded novel nominated for Booker Prize

Paul Kingsnorth's 'The Wake' is in contention for the prestigious award
Vladimir Putin employs a full-time food taster to ensure his meals aren't poisoned

Vladimir Putin employs a full-time food taster

John Walsh salutes those brave souls who have, throughout history, put their knives on the line
Tour de France effect brings Hollywood blockbusters to Yorkshire

Tour de France effect brings Hollywood blockbusters to Yorkshire

A $25m thriller starring Sam Worthington to be made in God's Own Country
Will The Minerva Project - the first 'elite' American university to be launched in a century - change the face of higher learning?

Will The Minerva Project change the face of higher learning?

The university has no lecture halls, no debating societies, no sports teams and no fraternities. Instead, the 33 students who have made the cut at Minerva, will travel the world and change the face of higher learning
The 10 best pedicure products

Feet treat: 10 best pedicure products

Bags packed and all prepped for holidays, but feet in a state? Get them flip-flop-ready with our pick of the items for a DIY treatment
Commonwealth Games 2014: Great Scots! Planes and pipers welcome in Glasgow's Games

Commonwealth Games 2014

Great Scots! Planes and pipers welcome in Glasgow's Games
Jack Pitt-Brooke: Manchester City and Patrick Vieira make the right stand on racism

Jack Pitt-Brooke

Manchester City and Patrick Vieira make the right stand on racism
How Terry Newton tragedy made iron men seek help to tackle their psychological demons

How Newton tragedy made iron men seek help to tackle their psychological demons

Over a hundred rugby league players have contacted clinic to deal with mental challenges of game