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25 per cent of Russian men die before they are 55, study reports

Toronto, Canada's largest city; former US vice-president Dick Cheney

O Canada, you're too dangerous for Dick Cheney

Peter Ustinov once called Toronto "New York run by the Swiss", meaning that Canada's largest city has everything the Big Apple does, but is just a bit cleaner, friendlier, more efficient and – well, Swiss. It might be an overstatement but, as a big metropolis, it does feel safe. But not safe enough for former US vice-president Dick Cheney, who yesterday pulled out of a talk in the city due to fears about his safety. Is he right to be scared? What are Toronto's potential dangers?

Fuel poverty deaths three times higher than government estimates

The number of people dying as a result of fuel poverty is three times higher than government estimates suggest, according to new academic research.

Leading article: Antibiotic overuse threatens us all

That drug-resistant blood-poisoning cases in Britain have risen by 30 per cent in less than five years is concerning enough. That the official analysis judges the soaring cases of untreatable E.coli to be just the "tip of the iceberg" of antibiotic resistance should be a spur to more concerted efforts to address the problem.

UK cancer cases could surge 30 per cent, report warns

New cases of cancer could rise by 30 per cent in the UK by 2030, experts warned, with poor diet, heavy alcohol consumption and an ageing population likely to play a major role.

Malaria deaths twice as high as was thought

Malaria is killing almost twice as many people around the world than was previously thought, a study has shown.

Gordon Brown calls for Global Fund for Education

Former prime minister Gordon Brown has called for the creation of a worldwide fund to combat a "hidden and silent emergency in education".

Wallace and Gromit creators in leprosy row

The creators of Wallace and Gromit and Chicken Run are at the centre of an angry storm surrounding their latest film amid accusations of bad taste and disability discrimination.

Poultry cull in Hong Kong after two dead birds tested positive for the deadly H5N1 strain of bird flu

Bird-flu victim 'had no direct contact with poultry'

Alarm in China after bus driver dies, and, in nearby Hong Kong, 19,000 chickens have been slaughtered

Chinese bus driver dies of bird flu

A Chinese bus driver who tested positive for the H5N1 bird flu virus died in a city bordering Hong Kong today, health officials said.

Leading article: No escaping the dangers of tobacco

Given the history of half-truths and special pleading which characterise the public pronouncements of tobacco companies, many people will find it unsurprising that the latest analysis casts doubt on previous industry-backed studies into the safety of cigarette additives. Indeed, independent scientists now claim that research published by Philip Morris a decade ago actually "obscured findings of toxicity".

5.6m people in South Africa with HIV/Aids – the largest epidemic in the world

World Aids Day: Thirty-four million reasons to act

The Aids crisis has affected so many millions that the numbers can be difficult to understand. Here, we look at the statistics behind the epidemic.

Government says 15 suicides an hour in India

The Indian government says the rate of suicide is increasing in the country and more than 15 people kill themselves every hour.

David Salisbury: Polio - a scourge that should be wiped out

If India can stop the spread, why has it not been eliminated everywhere?

Leading article: A sensible review of breast screening

Does screening for breast cancer do more harm than good? Once, a question like that would have been dismissed as heretical nonsense. After all, according to the Government's official line, 1,400 lives a year are saved by screening. But over the past few years evidence has begun to be raised suggesting that the harm may outweigh the benefits. A "better safe than sorry" approach can lead to over-diagnosis and unnecessary mutilating surgery for a lesion that was not going to cause harm.

Contagion (12A)

Starring: Matt Damon, Jude Law, Kate Winslet

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Pompeii, Capri & the Bay of Naples
Seven Cities of Italy
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Minoan Crete and Santorini
Prices correct as of 17 April 2015
Where the spooks get their coffee fix: The busiest Starbucks in the US is also the most secretive

The secret CIA Starbucks

The coffee shop is deep inside the agency's forested Virginia compound
Revealed: How the Establishment closed ranks over fallout from Loch Ness Monster 'sighting'

How the Establishment closed ranks over fallout from Nessie 'sighting'

The Natural History Museum's chief scientist was dismissed for declaring he had found the monster
One million Britons using food banks, according to Trussell Trust

One million Britons using food banks

Huge surge in number of families dependent on emergency food aid
Excavation at Italian cafe to fix rising damp unearths 2,500 years of history in 3,000 amazing objects

2,500 years of history in 3,000 amazing objects

Excavation at Italian cafe to fix rising damp unearths trove
The Hubble Space Telescope's amazing journey, 25 years on

The Hubble Space Telescope's amazing journey 25 years on

The space telescope was seen as a costly flop on its first release
Did Conservative peer Lord Ashcroft quit the House of Lords to become a non-dom?

Did Lord Ashcroft quit the House of Lords to become a non-dom?

A document seen by The Independent shows that a week after he resigned from the Lords he sold 350,000 shares in an American company - netting him $11.2m
Apple's ethnic emojis are being used to make racist comments on social media

Ethnic emojis used in racist comments

They were intended to promote harmony, but have achieved the opposite
Sir Kenneth Branagh interview: 'My bones are in the theatre'

Sir Kenneth Branagh: 'My bones are in the theatre'

The actor-turned-director’s new company will stage five plays from October – including works by Shakespeare and John Osborne
The sloth is now the face (and furry body) of three big advertising campaigns

The sloth is the face of three ad campaigns

Priya Elan discovers why slow and sleepy wins the race for brands in need of a new image
How to run a restaurant: As two newbies discovered, there's more to it than good food

How to run a restaurant

As two newbies discovered, there's more to it than good food
Record Store Day: Remembering an era when buying and selling discs were labours of love

Record Store Day: The vinyl countdown

For Lois Pryce, working in a record shop was a dream job - until the bean counters ruined it
Usher, Mary J Blige and Will.i.am to give free concert as part of the Global Poverty Project

Mary J Blige and Will.i.am to give free concert

The concert in Washington is part of the Global Citizen project, which aims to encourage young people to donate to charity
10 best tote bags

Accessorise with a stylish shopper this spring: 10 best tote bags

We find carriers with room for all your essentials (and a bit more)
Paul Scholes column: I hear Manchester City are closing on Pep Guardiola for next summer – but I'd also love to see Jürgen Klopp managing in England

Paul Scholes column

I hear Manchester City are closing on Pep Guardiola for next summer – but I'd also love to see Jürgen Klopp managing in England
Jessica Ennis-Hill: 'I just want to give it my best shot'

Jessica Ennis-Hill: 'I just want to give it my best shot'

The heptathlete has gone from the toast of the nation to being a sleep-deprived mum - but she’s ready to compete again. She just doesn't know how well she'll do...