Adele beat off stiff competition from Rihanna, Carly Rae Jepsen and Katy Perry to scoop best pop solo performance at the Grammy Awards and lead the British charge.
Receiving the gong for "Set Fire to the Rain [live]" from her “good luck charm” J-Lo, the singer sent “a big love to all the other girls and all us females doing this, cause we work so hard, we make it look so easy”.
Adele, who scooped a record haul of six Grammys at last year’s awards, is set to perform "Skyfall" at the 2013 Oscars on 24 February, where she is hotly tipped to win the original score gong for her 007 theme.
Having stormed the Billboard charts last year it was no surprise that British folk-rock band Mumford & Sons scooped album of the year for their second LP Babel.
Marcus Mumford, who collected his award from Adele, said: “We figured we weren’t going to win anything because The Black Keys have been sweeping up all day, rightfully so.”
The band also won best long form music video for "Big Easy Express".
British icons Sir Elton John, Paul McCartney and Sting were also there.
No stranger to Grammy awards, Sir Elton dedicated his performance to the victims of Sandy Hook Elementary School shooting last December.
Former Police frontman Sting also took to the stage to pay tribute to reggae star Bob Marley, and collaborated with American singer Bruno Mars performing their hits "Locked Out Of Heaven" and "Walking On The Moon" together.
Paul McCartney won his 15th Grammy, taking home best traditional pop vocal album for Kisses On The Bottom. It was his first solo album to win the top honour in its category.
Another top winner on the night was Belgian-Australian Gotye who picked up record of the year for "Somebody That I Used to Know", which features Kimbra.
Emerging American indie-pop act Fun scooped up two Grammys for new artist and song of the year.
Later in the ceremony Adele and fellow Brit Ed Sheeran were later pictured giving glaring looks to Chris Brown when he failed to give Frank Ocean a standing ovation.
Rapper Brown was accompanying his girlfriend Rihanna to the awards four years after the pair missed the ceremony after he assaulted her.
Brown and Ocean were recently involved in a brawl outside a recording studio.
Winners in full:
Album Of The Year - Mumford & Sons - Babel
Record Of The Year - 'Somebody That I Used To Know'
Song Of The Year - fun. featuring Janelle Monáe - 'We Are Young'
Best New Artist - fun.
Best Pop Solo Performance - Adele - 'Set Fire To The Rain' [Live at the Royal Albert Hall]
Best Pop Duo/Group Performance - Gotye featuring Kimbra - 'Somebody That I Used To Know'
Best Pop Vocal Album - Kelly Clarkson - Stronger
Best Dance Recording - Skrillex featuring Sirah – 'Bangarang'
Best Dance/Electronica Album - Skrillex - Bangarang
Best Alternative Music Album - Gotye - Making Mirrors
Best Rock Performance - The Black Keys - 'Lonely Boy'
Best Hard Rock/Metal Performance - Halestorm - 'Love Bites (So Do I)'
Best Rock Song - The Black Keys - 'Lonely Boy'
Best Rock Album - The Black Keys - El Camino
Best R&B Performance - Usher - 'Climax'
Best Traditional R&B Performance - Beyoncé - 'Love on Top'
Best R&B Song - Miguel - 'Adorn'
Best Urban Contemporary Album - Frank Ocean - Channel Orange
Best R&B Album - Robert Glasper Experiment - Black Radio
Best Rap Performance - Jay-Z & Kanye West - 'N****s in Paris'
Best Rap/Sung Collaboration - Jay-Z & Kanye West Featuring Frank Ocean & The-Dream - 'No Church In The Wild'
Best Rap Song - Jay-Z & Kanye West - 'N****s in Paris'
Best Rap Album - Drake - Take Care
Best Country Solo Performance - Carrie Underwood - 'Blown Away'
Best Country Album - Zac Brown Band - Uncaged
Best Americana Album - Bonnie Raitt - Slipstream
Best Score Soundtrack For Visual Media - Trent Reznor and Atticus Ross - The Girl With the Dragon Tattoo
Best Song Written For Visual Media - 'Safe and Sound' (from The Hunger Games) Producer of the Year (Non Classical) - Dan Auerbach
Best Short Form Music Video - Rihanna featuring Calvin Harris - 'We Found Love'