Speaking to the BBC, Foxx acknowledged the crash, which took place in February, but said he would challenge people to compare the incident to "the number of crashes that occurred on the same day that were the result of human behaviour."
"I think question here isn't comparing the automated car to perfection, I think it's a relative comparison to what we have now on the roads, which is you and I, and our eyeballs and our brains," he said.
The Google car crash happened when a driverless Lexus SUV scraped the side of a public bus while pulling out into traffic at low speeds.
Google admitted the car was at fault, saying the software predicted the bus would let the car out because it was ahead of it.
In a statement, Google said: "This type of misunderstanding happens between human drivers on the road every day."
The company said it had now reviewed the incident, and refined the car's software to make it understand that large vehicles are less likely to give way to other vehicles.
Foxx is a confirmed fan of driverless cars. In January, he announced an upcoming $4 billion scheme to support and advance the development of the technology, as well as a proposed change in regulations that would pave the way for autonomous vehicles to hit America's roads.
In the interview, Foxx admitted there was "no question" that the technology has the potential to cause disruption, but said it could also reduce 80 per cent of the car crashes that occur.
Google's cars have already travelled over 1 million miles without anyone at the wheel. They hope the vehicles will be released to the public in 2020.Reuse content