Anger as NHS deem prostate cancer drug Cabazitaxel 'too expensive' - Health News - Health & Families - The Independent

Anger as NHS deem prostate cancer drug Cabazitaxel 'too expensive'

 

A life-extending drug hailed as a breakthrough for prostate cancer sufferers is too expensive to be used on the NHS, watchdogs ruled today.

Cabazitaxel, which is marketed as Jevtana, can extends the life of late-stage patients by an average of three months.

The National Institute for Health and Clinical Excellence (Nice), which decides which drugs should be offered on the NHS, today confirmed its original decision in January, rejecting an appeal by the drug's manufacturers Sanofi.

But cancer charities said the decision could mean a postcode lottery and effectively prevent thousands of men from accessing life-extending treatment.

Each year around 37,000 men in the UK are diagnosed with prostate cancer and 10,000 die from the disease.

It is the second most common cause of cancer death in men, accounting for 13%.

Nice said that while the drug is clinically effective, at £22,000 per patient it does not offer value for money for the NHS, and there are concerns over side-effects.

Nice chief executive Sir Andrew Dillon said: "We need to be sure that new treatments provide sufficient benefits to patients to justify the significant resources the NHS would need to make available.

"Although cabazitaxel can extend life for some patients, its price remains well above what the independent committee appraising this drug considered acceptable, given the benefits it offers.

"Cabazitaxel is also associated with a number of side effects, and the committee was concerned about the nature of the health-related quality of life information provided by the manufacturer."

Whenever a new drug is made available, the money to fund it has to come from elsewhere in the NHS.

Nice said it must look at the benefit for patients the NHS can get for the money the drug company is asking.

But Professor Jonathan Waxman of Imperial College London said the cost argument was false.

"This decision seeks to limit what we as clinicians can do for our patients and their families," he said.

"The cost argument on which Nice bases their decision is false, giving a much higher estimate of true cost than applies in reality.

"As a result, yet another successful and effective cancer treatment is denied our patients, a mortifying blow to cancer care in England.

"As the only route to access is now the Cancer Drugs Fund, a temporary arrangement that operates very differently around the country, I fear we're heading towards a re-emergence of the postcode lottery."

Emma Malcolm, chief executive of the charity Prostate Action, said: "Cabazitaxel is one of only two licensed drugs available in the UK that offers the hope of precious extra time and quality of life benefits to men living with advanced prostate cancer.

"Nice's decision not to recommend this drug means that men in England with advanced prostate cancer have to access it through the Cancer Drugs Fund.

"We know that there are inconsistencies across the country with how this fund is awarded, which means some men will only be able to access one of these drugs in some areas.

"Men with advanced prostate cancer have so few treatment options available to them that they should be able to access both of these new treatments."

The Cancer Drugs Fund, set up in 2010 to allow access to drugs rejected by Nice or not yet licensed, is only available until 2014 and only applies in England.

Prostate cancer patients are also waiting for Nice to issue their decision on abiraterone, another life-extending treatment, which is due soon.

PA

Life and Style
tech
Arts and Entertainment
Robin Thicke's video for 'Blurred Lines' has been criticised for condoning rape
music
News
Paper trail: the wedding photograph found in the rubble after 9/11 – it took Elizabeth Keefe 13 years to find the people in it
newsWho are the people in this photo? It took Elizabeth Stringer Keefe 13 years to find out
Voices
Yes supporters gather outside the Usher Hall, which is hosting a Night for Scotland in Edinburgh
voicesBen Judah: Is there a third option for England and Scotland that keeps everyone happy?
PROMOTED VIDEO
Life and Style
ebooksA superb mix of recipes serving up the freshest of local produce in a delicious range of styles
Life and Style
ebooksFrom the lifespan of a slug to the distance to the Sun: answers to 500 questions from readers
Arts and Entertainment
Matt Damon as Jason Bourne in The Bourne Ultimatum (2007)
filmMatt Damon in talks to return
News
peopleThe report and photo dedicated to the actress’s decolletage has, unsurprisingly, provoked anger
Arts and Entertainment
Evil eye: Douglas Adams in 'mad genius' pose
booksNew biography sheds light on comic genius of Douglas Adams
Life and Style
tech... and together they're worth at least £100 million
Arts and Entertainment
While many films were released, few managed to match the success of James Bond blockbuster 'Skyfall'
filmsDaniel Craig is believed to be donning skies as 007 for the first time
Arts and Entertainment
Fringe show: 'Cilla', with Sheridan Smith in the title role and Aneurin Barnard as her future husband Bobby Willis
tvEllen E Jones on ITV's 'Cilla'
Life and Style
Bono and Apple CEO Tim Cook announced U2's surprise new album at the iPhone 6 launch
tech(but you can't escape: Bono is always on your iPhone)
Sport
Tim Wiese
sport
Life and Style
Kim Kardashian drawn backlash over her sexy swimsuit selfie, called 'disgusting' and 'nasty'
fashionCritics say magazine only pays attention to fashion trends among rich, white women
Arts and Entertainment
TVShows like Agents of S.H.I.E.L.D are little more than marketing tools
Arts and Entertainment
Hit the roof: hot-tub cinema east London
architectureFrom pools to football pitches, rooftop living is looking up
Latest stories from i100
Have you tried new the Independent Digital Edition apps?

ES Rentals

    Independent Dating
    and  

    By clicking 'Search' you
    are agreeing to our
    Terms of Use.

    iJobs Job Widget
    iJobs General

    Bookkeeper / Accounts Administrator - Central London, £30-40k

    £30000 - £40000 per annum: Ashdown Group: Bookkeeper - Central London, £30-40k...

    Permanent KS2 Teacher required

    Negotiable: Randstad Education Ilford: A Redbridge based Primary School is see...

    NVQ Assessor Level 2 & 3 Sport Development

    £19200 - £26880 per annum: Randstad Education Manchester Secondary: In NVQ Ass...

    Secondary supply teachers required in Newmarket

    £21000 - £35000 per annum: Randstad Education Cambridge: Secondary supply teac...

    Day In a Page

    Mystery of the Ground Zero wedding photo

    A shot in the dark

    Mystery of the wedding photo from Ground Zero
    His life, the universe and everything

    His life, the universe and everything

    New biography sheds light on comic genius of Douglas Adams
    Save us from small screen superheroes

    Save us from small screen superheroes

    Shows like Agents of S.H.I.E.L.D are little more than marketing tools
    Reach for the skies

    Reach for the skies

    From pools to football pitches, rooftop living is looking up
    These are the 12 best hotel spas in the UK

    12 best hotel spas in the UK

    Some hotels go all out on facilities; others stand out for the sheer quality of treatments
    These Iranian-controlled Shia militias used to specialise in killing American soldiers. Now they are fighting Isis, backed up by US airstrikes

    Widespread fear of Isis is producing strange bedfellows

    Iranian-controlled Shia militias that used to kill American soldiers are now fighting Isis, helped by US airstrikes
    Topshop goes part Athena poster, part last spring Prada

    Topshop goes part Athena poster, part last spring Prada

    Shoppers don't come to Topshop for the unique
    How to make a Lego masterpiece

    How to make a Lego masterpiece

    Toy breaks out of the nursery and heads for the gallery
    Meet the ‘Endies’ – city dwellers who are too poor to have fun

    Meet the ‘Endies’ – city dwellers who are too poor to have fun

    Urbanites are cursed with an acronym pointing to Employed but No Disposable Income or Savings
    Paisley’s decision to make peace with IRA enemies might remind the Arabs of Sadat

    Ian Paisley’s decision to make peace with his IRA enemies

    His Save Ulster from Sodomy campaign would surely have been supported by many a Sunni imam
    'She was a singer, a superstar, an addict, but to me, her mother, she is simply Amy'

    'She was a singer, a superstar, an addict, but to me, her mother, she is simply Amy'

    Exclusive extract from Janis Winehouse's poignant new memoir
    Is this the role to win Cumberbatch an Oscar?

    Is this the role to win Cumberbatch an Oscar?

    The Imitation Game, film review
    England and Roy Hodgson take a joint step towards redemption in Basel

    England and Hodgson take a joint step towards redemption

    Welbeck double puts England on the road to Euro 2016
    Relatives fight over Vivian Maier’s rare photos

    Relatives fight over Vivian Maier’s rare photos

    Pictures removed from public view as courts decide ownership
    ‘Fashion has to be fun. It’s a big business, not a cure for cancer’

    ‘Fashion has to be fun. It’s a big business, not a cure for cancer’

    Donatella Versace at New York Fashion Week